Stock Fundamentals

Company Information

Company Name
Zai Lab Ltd
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US98887Q1040
CIK: 0001704292
CUSIP: 98887Q104
Currency: USD
Full Time Employees: 1,869
Phone: 86 21 6163 2588
Fiscal Year End: December
IPO Date: Sep 20, 2017
Description:

Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammatory demyelinating polyneuropathy; NUZYRA for community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections; Optune for glioblastoma multiforme; Qinlock for gastrointestinal stromal tumors; Xacduro for treating hospital-acquired and ventilator-associated bacterial pneumonia caused by a cinetobacter baumannii-calcoaceticus complex; and Augtyro for the treatment of ROS proto-oncogene 1 and non-small cell lung cancer. The company's oncology pipeline includes bemarituzumab, tumor treating fields, tisotumab vedotin, and repotrectinib; and immunology, neuroscience, and infectious disease pipeline comprises efgartigimod and xanomeline and trospium chloride. Zai Lab Limited has license and collaboration agreements with Tesaro, Inc. to develop, manufacture, and commercialize niraparib; NovoCure Ltd. to develop and commercialize Tumor Treating Fields; Deciphera Pharmaceuticals, LLC to develop and commercialize ripretinib; Paratek Bermuda Ltd. to develop, manufacture, and commercialize omadacycline; argenx BV to develop and commercialize efgartigimod; Bristol-Myers Squibb Company to develop and commercialize tisotumab vedotin and repotrectinib; Amgen Inc. to develop and commercialize bemarituzumab; Innoviva, Inc. to develop and commercialize Sulbactam-Durlobactam; and Karuna Therapeutics, Inc. to develop and commercialize Xanomeline and trospium chloride, as well as strategic collaboration with Pfizer Inc. for sulbactam and durlobactam. The company was incorporated in 2013 and is headquartered in Pudong, China.

Address:

Building B, Pudong, China, 201203

Directors & Officers

Name Title Year Born
Dr. Ying Du Ph.D. Founder, Chairperson & CEO 1966
Mr. Joshua L. Smiley President & COO 1970
Dr. Rafael G. Amado M.D. President and Head of Global Research & Development 1964
Dr. Yajing Chen Ph.D. Chief Financial Officer 1968
Mr. Frazor Titus Edmondson III, J.D. Chief Legal Officer & Corporate Secretary 1966
Ms. Christine Chiou Senior VP & Head of Investor Relations NA
Dr. James Yan DABT, M.D., Ph.D. Chief Operating Officer of R&D 1964
Mr. Tong Zhu Chief Commercial Officer of Greater China 1978
Dr. Shan He Ph.D. Senior VP & Chief Business Officer NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
RTW INVESTMENTS, LLC 6.96M Dec 31, 2025 6.21% $1.23 203.71%
Capital World Investors 6.08M Sep 30, 2025 5.42% $0.03 0.69%
ClearBridge Advisors, LLC 3.52M Sep 30, 2025 3.14% $0.09 -12.28%
HHG PLC 2.05M Sep 30, 2025 1.83% $0.03 -6.75%
Frazier Life Sciences Management, L.P. 1.90M Dec 31, 2025 1.70% $0.90 16.90%
FMR Inc 1.44M Dec 31, 2025 1.29% $0.00 -69.36%
BAMCO Inc 1.42M Dec 31, 2025 1.27% $0.07 3.41%
ADAR1 Capital Management LLC 1.25M Dec 31, 2025 1.11% $1.61 43.48%
Citadel Advisors Llc 987.04K Sep 30, 2025 0.88% $0.01 169.53%
T. Rowe Price Associates, Inc. 948.67K Sep 30, 2025 0.85% $0.00 519.90%
Allianz Asset Management AG 815.00K Sep 30, 2025 0.73% $0.03 -12.55%
Rock Springs Capital Management LP 811.55K Dec 31, 2025 0.72% $0.73 2.57%
Wellington Management Company LLP 752.86K Dec 31, 2025 0.67% $0.00 -56.19%
MPM Oncology Impact Management LP 745.06K Sep 30, 2025 0.66% $4.13 0.00%
CAM Group Holding A/S 510.00K Sep 30, 2025 0.46% $0.27 0.00%
BlackRock Inc 473.56K Sep 30, 2025 0.42% $0.00 4.01%
B Group, Inc 400.00K Dec 31, 2025 0.36% $5.21 0.00%
Legal & General Group PLC 387.80K Dec 31, 2025 0.35% $0.00 1.40%
Walleye Trading Advisors, LLC 373.40K Dec 31, 2025 0.33% $0.02 0.00%
UBS Group AG 306.55K Sep 30, 2025 0.27% $0.00 26.86%

Shares Statistics

Shares Outstanding: 112.07M
Shares Float: 1.02B
% Insiders: 182.50%
% Institutions: 3,006.60%
Short % Float: 3.41%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 RTW INVESTMENTS, LLC 6.96M 6.21% ▲ 203.71% Dec 31, 2025
2 Capital World Investors 6.08M 5.42% ▲ 0.69% Sep 30, 2025
3 ClearBridge Advisors, LLC 3.52M 3.14% ▼ 12.28% Sep 30, 2025
4 HHG PLC 2.05M 1.83% ▼ 6.75% Sep 30, 2025
5 Frazier Life Sciences Management, L.P. 1.90M 1.70% ▲ 16.90% Dec 31, 2025
6 FMR Inc 1.44M 1.29% ▼ 69.36% Dec 31, 2025
7 BAMCO Inc 1.42M 1.27% ▲ 3.41% Dec 31, 2025
8 ADAR1 Capital Management LLC 1.25M 1.11% ▲ 43.48% Dec 31, 2025
9 Citadel Advisors Llc 987.04K 0.88% ▲ 169.53% Sep 30, 2025
10 T. Rowe Price Associates, Inc. 948.67K 0.85% ▲ 519.90% Sep 30, 2025

Valuation Metrics

Enterprise Value: $1.66B
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $2.15B
EBITDA: $-214.42M
Book Value: $6.47
Earnings/Share: $-1.90
Profit Margin: -38.15%
Operating Margin: -54.40%
ROA (TTM): -12.16%
ROE (TTM): -22.56%
Revenue (TTM): $460.16M
Revenue/Share (TTM): $4.20
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 17.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 2.45x 0.29x 0.39x -44.05x -1.33x
2024-12-31 3.51x 0.17x 0.29x -125.16x -0.60x
2023-12-31 4.63x 0.01x 0.23x -25.14x -0.02x
2022-12-31 8.04x 0.01x 0.14x -27.73x -0.02x
2021-12-31 7.78x 0.00x 0.14x -208.97x -0.01x
2020-12-31 12.40x 0.00x 0.10x -1,667.41x -0.02x
2019-12-31 6.27x 0.04x 0.17x -693.50x -0.05x
2018-12-31 5.51x 0.01x 0.17x -3,573.50x -0.03x
2017-12-31 19.11x 10.18x 0.06x -40.90x -47.09x
2016-12-31 16.25x 0.00x 1.58x -37.88x 0.00x
2015-12-31 3.36x 0.00x 2.32x -9.78x 0.00x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Dec 31, 2025 Rafael Amado N/A Sale 10.79K $17.43 $188.02K
Nov 03, 2025 Yajing Chen N/A Sale 240.00 $26.83 $6.44K
Sep 10, 2025 Joshua L Smiley N/A Purchase 10.00K $28.91 $289.10K
Aug 18, 2025 Joshua L Smiley N/A Sale 6.64K $36.24 $240.67K
Aug 15, 2025 Yajing Chen N/A Sale 1.44K $35.42 $50.93K
Aug 13, 2025 Ying Du N/A Sale 46.39K $35.47 $1.65M
Aug 11, 2025 Ying Du N/A Sale 50.00K $34.64 $1.73M
Aug 08, 2025 Rafael Amado N/A Sale 3.00K $35.00 $105.00K
Aug 08, 2025 Yajing Chen N/A Sale 4.10K $34.01 $139.30K
Aug 08, 2025 Ying Du N/A Sale 50.00K $34.74 $1.74M
Jul 02, 2025 Ying Du N/A Sale 7.07K $35.23 $249.15K
Jun 30, 2025 Ying Du N/A Sale 6.92K $35.52 $245.73K
Jun 26, 2025 Yajing Chen N/A Sale 2.68K $36.13 $96.65K
Jun 26, 2025 Ying Du N/A Sale 23.67K $36.13 $855.16K
Jun 20, 2025 William Lis N/A Sale 13.81K $35.67 $492.75K
Jun 02, 2025 Yajing Chen N/A Sale 9.62K $30.00 $288.54K
May 14, 2025 Ying Du N/A Sale 46.39K $28.09 $1.30M
May 13, 2025 Ying Du N/A Sale 50.00K $28.57 $1.43M
Apr 04, 2025 Frazor Titus Edmondson III N/A Sale 1.87K $33.11 $62.05K
Apr 04, 2025 Yajing Chen N/A Sale 924.00 $33.11 $30.59K

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