XFOR
X4 Pharmaceuticals Inc

XFOR.US x4pharma.com + Research + Basket
Healthcare · Biotechnology
CIK 0001501697
Employees 45
Phone 857 529 8300
Fiscal year end December
IPO Nov 16, 2017
Address 61 North Beacon Street, Boston, MA, United States, 02134
3.35
-0.01 (-0.30%)
USD · NASDAQ
52-week range
2.43
4.83
Trading at 38% of the 52-week range
Market Cap
332.14M
P/E Ratio
167.50
Forward P/E
0.00
Book Value
1.62
Div. Yield
N/A
% Institutions
103.82%
% Insiders
0.445%
1 Year

-16.0%
3 Year

-86.1%
10 Year

-99.9%
Description
X4 Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases of the immune system. It offers XOLREMDI, an orally small-molecule selective antagonist of chemokine receptor CXCR4, which is in phase 3 clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. It has a license agreement with Abbisko Therapeutics Co Ltd. to manufacture and distribute XOLREMDI in mainland China, Taiwan, Hong Kong and Macau; Norgine to develop, manufacture, and commercialize mavorixafor in Europe, Australia, and New Zealand; and Genzyme Corporation for CXCR4 receptor to develop and commercialize products containing licensed compounds for all therapeutic, prophylactic and diagnostic uses. The company is headquartered in Boston, Massachusetts.
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People

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Directors & Officers

Name	Title	Year Born
Dr. Adam R. Craig M.B.A., M.D., Ph.D.	Executive Chair	1966
Mr. John P. Volpone M.B.A.	President & COO	1975
Mr. David H. Kirske	CFO, Treasurer & Corporate Secretary	1954
Dr. Richard Peters M.D., Ph.D.	Founder	1962
Dr. Renato T. Skerlj Ph.D.	Founder	NA
Dr. Keith T. Flaherty M.D.	Founder & Member of Corporate Advisory Board	1971
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Oct 23, 2025	Adam R Craig	N/A	Purchase	86.21K	$2.90	$250.00K	SEC
May 16, 2025	Mark Baldry	N/A	Purchase	1.03K	$2.48	$2.56K	SEC
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
Morgan Stanley - Brokerage Accounts	9.46M	Jun 30, 2026	9.54%	$0.00	-0.06%
FMR Inc	8.32M	Jun 30, 2026	8.39%	$0.00	2.69%
Bain Capital Life Sciences Investors, LLC	7.97M	Jun 30, 2026	8.04%	$2.21	0.00%
Perceptive Advisors LLC	7.93M	Jun 30, 2026	8.00%	$0.56	17.75%
Kalehua Capital Management LLC	7.45M	Jun 30, 2026	7.51%	$11.09	0.00%
Saturn V Capital Management LLC	6.97M	Jun 30, 2026	7.03%	$4.67	8.00%
Empery Asset Management, LP	6.93M	Jun 30, 2026	6.99%	$37.43	-22.51%
Deep Track Capital, LP	5.88M	Jun 30, 2026	5.93%	$0.40	-7.27%
BlackRock Inc	5.55M	Jun 30, 2026	5.60%	$0.00	358.40%
Nantahala Capital Management, LLC	4.90M	Jun 30, 2026	4.94%	$0.38	100.00%
Vanguard Capital Management, LLC	3.72M	Jun 30, 2026	3.75%	$0.00	6.24%
Rosalind Advisors, Inc.	3.21M	Jun 30, 2026	3.24%	$5.58	0.00%
BRAIDWELL LP	2.92M	Jun 30, 2026	2.95%	$0.50	-10.70%
Blackstone Inc	2.68M	Jun 30, 2026	2.71%	$0.04	0.00%
Trails Edge Capital Partners, LP	2.57M	Jun 30, 2026	2.59%	$1.91	0.00%
Bvf Inc	2.23M	Jun 30, 2026	2.25%	$0.27	0.00%
Geode Capital Management, LLC	2.10M	Jun 30, 2026	2.12%	$0.00	123.26%
VR Adviser, LLC	1.93M	Jun 30, 2026	1.95%	$0.27	485.21%
Samsara BioCapital, LLC	1.40M	Jun 30, 2026	1.41%	$0.54	-23.85%
State Street Corp	1.30M	Jun 30, 2026	1.31%	$0.00	221.17%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Fidelity Small Cap Growth	3.39M	3.42%	▲ 0.00%	Jul 31, 2026
2	Vanguard MStar Total Stk Mkt Idx Invest	2.60M	2.62%	▲ 0.00%	Sep 30, 2026
3	Morgan Stanley Inst Inception I	2.31M	2.33%	▼ 1.07%	Jun 30, 2026
4	iShares Russell 2000 ETF	2.14M	2.16%	▼ 1.14%	Sep 30, 2026
5	EQ/Morgan Stanley Small Cap Growth K	1.92M	1.93%	▲ 0.00%	Aug 31, 2026
6	Fidelity Small Cap Growth K6	1.69M	1.70%	▲ 0.00%	Jul 31, 2026
7	Fidelity Select Biotechnology	1.43M	1.44%	▲ 0.00%	Aug 31, 2026
8	Fidelity Advisor Biotechnology I	1.34M	1.35%	▲ 0.00%	Aug 31, 2026
9	Fidelity Small Cap Index	884.76K	0.89%	▲ 1.02%	Jul 31, 2026
10	iShares Russell 2000 Value ETF	761.68K	0.77%	▲ 0.15%	Sep 30, 2026
Financial Highlights

▼
Market Cap: $332.14M
EBITDA: $-79.00M
P/E Ratio: $167.50
Book Value: $1.62
Earnings/Share: $0.02
Profit Margin: 0.00%
Operating Margin: -186.13%
ROA (TTM): -28.15%
ROE (TTM): -113.08%
Revenue (TTM): $15.85M
Revenue/Share (TTM): $0.16
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 346.30%
Valuation Metrics

Enterprise Value: $191.48M
Trailing P/E: 167.50
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 99.15M
Shares Float: 57.22M
% Insiders: 0.445%
% Institutions: 103.82%
Shares Short: 7.49M
Shares Short (Prior Month): 7.59M
Short Ratio: 7.58
Short % Float: 7.57%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$35.11M
Cost of Goods Sold
adjust
$-6.26M
Gross Profit
subtotal
$28.86M
SG&A
adjust
$-43.52M
R&D
adjust
$-72.22M
Operating Income
subtotal
$-86.88M
Other / Non-Operating Items
adjust
$7.68M
Net Income
subtotal
$-79.20M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "XFOR",
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        "Name": "X4 Pharmaceuticals Inc",
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        },
        "Trend": {
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                "date": "2027-12-31",
                "period": "+1y",
                "growth": "-0.1490",
                "earningsEstimateAvg": "-0.7675",
                "earningsEstimateLow": "-1.0000",
                "earningsEstimateHigh": "-0.6500",
                "earningsEstimateYearAgoEps": "-0.6680",
                "earningsEstimateNumberOfAnalysts": "4.0000",
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}
X4 Pharmaceuticals Inc

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