XFOR
X4 Pharmaceuticals Inc

XFOR.US x4pharma.com
Healthcare · Biotechnology
3.62
+0.12 (+3.29%)
USD · NASDAQ
52-week range
2.80
4.83
Trading at 40% of the 52-week range
Market Cap
347.01M
P/E Ratio
2.45
Forward P/E
0.00
Book Value
1.62
Div. Yield
N/A
% Institutions
100.14%
% Insiders
0.440%
1 Year

+6.1%
3 Year

-90.1%
10 Year

-99.9%
Description
X4 Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases of the immune system. It offers XOLREMDI, an orally small-molecule selective antagonist of chemokine receptor CXCR4, which is in phase 3 clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome. It has a license agreement with Abbisko Therapeutics Co Ltd. to manufacture and distribute XOLREMDI in mainland China, Taiwan, Hong Kong and Macau; Norgine to develop, manufacture, and commercialize mavorixafor in Europe, Australia, and New Zealand; and Genzyme Corporation for CXCR4 receptor to develop and commercialize products containing licensed compounds for all therapeutic, prophylactic and diagnostic uses. The company is headquartered in Boston, Massachusetts.
People

▼
Directors & Officers

Name	Title	Year Born
Dr. Adam R. Craig M.B.A., M.D., Ph.D.	Executive Chair	1966
Mr. John P. Volpone M.B.A.	President & COO	1975
Mr. David H. Kirske	CFO, Treasurer & Corporate Secretary	1954
Dr. Richard Peters M.D., Ph.D.	Founder	1962
Dr. Renato T. Skerlj Ph.D.	Founder	NA
Dr. Keith T. Flaherty M.D.	Founder & Member of Corporate Advisory Board	1971
Insider Trading

Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Oct 23, 2025	Adam R Craig	N/A	Purchase	86.21K	$2.90	$250.00K
May 16, 2025	Mark Baldry	N/A	Purchase	1.03K	$2.48	$2.56K
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
Morgan Stanley - Brokerage Accounts	9.47M	Mar 31, 2026	9.55%	$0.00	15.34%
FMR Inc	8.10M	Mar 31, 2026	8.17%	$0.00	-4.66%
Bain Capital Life Sciences Investors, LLC	7.97M	Mar 31, 2026	8.04%	$2.97	0.00%
Perceptive Advisors LLC	7.93M	Jun 30, 2026	8.00%	$0.56	17.75%
Kalehua Capital Management LLC	7.45M	Mar 31, 2026	7.51%	$11.83	100.00%
Saturn V Capital Management LLC	6.97M	Jun 30, 2026	7.03%	$4.67	8.00%
Empery Asset Management, LP	6.93M	Jun 30, 2026	6.99%	$37.43	-22.51%
Deep Track Capital, LP	5.88M	Jun 30, 2026	5.93%	$0.40	-7.27%
Vanguard Capital Management, LLC	3.50M	Mar 31, 2026	3.53%	$0.00	0.00%
BRAIDWELL LP	3.27M	Mar 31, 2026	3.30%	$0.45	-2.85%
Rosalind Advisors, Inc.	3.21M	Mar 31, 2026	3.24%	$5.33	23.36%
Blackstone Inc	2.68M	Mar 31, 2026	2.71%	$0.04	0.00%
Trails Edge Capital Partners, LP	2.57M	Jun 30, 2026	2.59%	$1.91	0.00%
Nantahala Capital Management, LLC	2.45M	Mar 31, 2026	2.47%	$0.37	0.00%
Bvf Inc	2.23M	Mar 31, 2026	2.25%	$0.29	0.00%
StemPoint Capital LP	1.70M	Mar 31, 2026	1.72%	$0.68	89.38%
Samsara BioCapital, LLC	1.40M	Jun 30, 2026	1.41%	$0.54	-23.85%
BlackRock Inc	1.21M	Mar 31, 2026	1.22%	$0.00	-1.22%
Woodline Partners LP	1.00M	Mar 31, 2026	1.01%	$0.02	0.02%
Geode Capital Management, LLC	939.73K	Mar 31, 2026	0.95%	$0.00	-0.08%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Fidelity Small Cap Growth	3.39M	3.42%	▲ 0.00%	Jun 30, 2026
2	Vanguard MStar Total Stk Mkt Idx Invest	2.60M	2.62%	▲ 0.00%	Jul 31, 2026
3	Morgan Stanley Inception	2.31M	2.33%	▼ 1.07%	Jun 30, 2026
4	Morgan Stanley Inst Inception I	2.31M	2.33%	▼ 1.07%	Jun 30, 2026
5	iShares Russell 2000 ETF	1.96M	1.98%	▼ 0.57%	Aug 31, 2026
6	EQ/Morgan Stanley Small Cap Growth K	1.92M	1.93%	▲ 5.40%	Jul 31, 2026
7	Fidelity Small Cap Growth K6	1.69M	1.70%	▲ 0.00%	Jun 30, 2026
8	Fidelity Select Biotechnology	1.43M	1.44%	▲ 0.00%	Jul 31, 2026
9	Fidelity Advisor Biotechnology I	1.34M	1.35%	▲ 0.00%	Jul 31, 2026
10	Vanguard Institutional Extnd Mkt Idx Tr	1.01M	1.02%	▼ 1.85%	Jul 31, 2026
Financial Highlights

▼
Market Cap: $347.01M
EBITDA: $-79.00M
P/E Ratio: $2.45
Book Value: $1.62
Earnings/Share: $1.43
Profit Margin: 0.00%
Operating Margin: -186.13%
ROA (TTM): -28.15%
ROE (TTM): -113.08%
Revenue (TTM): $15.85M
Revenue/Share (TTM): $0.16
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 346.30%
Valuation Metrics

Enterprise Value: $216.27M
Trailing P/E: 2.45
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 99.15M
Shares Float: 62.80M
% Insiders: 0.440%
% Institutions: 100.14%
Short % Float: 7.27%
Stock Price History

▼
1 Year Price History

3 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Revenue, Net Income & Operating Cash Flow (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$35.11M
Cost of Goods Sold
adjust
$-6.26M
Gross Profit
subtotal
$28.86M
SG&A
adjust
$-43.52M
R&D
adjust
$-72.22M
Operating Income
subtotal
$-86.88M
Other / Non-Operating Items
adjust
$7.68M
Net Income
subtotal
$-79.20M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "XFOR",
        "Type": "Common Stock",
        "Name": "X4 Pharmaceuticals Inc",
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}
X4 Pharmaceuticals Inc

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