Fundamentals - AlphaKey Financial

People

▼
Directors & Officers

Name	Title	Year Born
Dr. Todd Harris Ph.D.	Co-Founder, CEO, President & Director	1979
Mr. Bhavesh Ashar M.B.A.	Chief Operating Officer	1969
Dr. Douglas Warner M.D.	Chief Medical Officer	1972
Mr. Daniel Bensen	Co-Founder & Chief Discovery Officer	1975
Ms. Julia Rueb	VP of Finance & Principal Accounting Officer	1986
Dr. Robert L. Hudkins Ph.D.	Chief Technology Officer	1955
Dr. Ronald V. Swanson Ph.D.	Chief Scientific Officer	1963
Mr. Ali D. Fawaz J.D.	General Counsel & Secretary	NA
Ms. Sarah Honig	Senior VP of Corporate Development & Strategy	NA
Liz Pagano	Chief Human Resources Officer	NA
Insider Trading

Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Mar 25, 2026	Gilla Kaplan	N/A	Sale	14.30K	$36.97	$528.49K
Dec 19, 2025	Robert J More	N/A	Sale	10.00K	$25.00	$250.00K
Nov 21, 2025	Robert J More	N/A	Sale	246.87K	$20.25	$5.00M
Jun 18, 2025	Gilla Kaplan	N/A	Sale	9.57K	$9.78	$93.58K
Jun 17, 2025	Gilla Kaplan	N/A	Sale	10.00	$10.35	$103.50
Jun 16, 2025	Gilla Kaplan	N/A	Sale	6.81K	$10.38	$70.73K
Jun 13, 2025	Gilla Kaplan	N/A	Sale	15.00K	$10.31	$154.65K
Jun 12, 2025	Gilla Kaplan	N/A	Sale	30.00K	$10.31	$309.30K
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
RA Capital Management, LLC	12.20M	Mar 31, 2026	20.51%	$4.95	0.00%
FMR Inc	7.75M	Mar 31, 2026	13.03%	$0.02	61,570.37%
Nextech Invest, Ltd.	4.06M	Mar 31, 2026	6.82%	$10.93	0.00%
HHG PLC	3.89M	Mar 31, 2026	6.54%	$0.07	32.54%
Alta Partners Management Company, L.P.	3.82M	Jun 30, 2026	6.43%	$95.92	0.00%
Farallon Capital Management, L.L.C.	3.58M	Mar 31, 2026	6.02%	$0.78	73.25%
TCG Crossover Management, LLC	3.25M	Mar 31, 2026	5.46%	$3.56	12.11%
COMMODORE CAPITAL LP	2.48M	Mar 31, 2026	4.16%	$5.48	-26.67%
BlackRock Inc	2.22M	Mar 31, 2026	3.73%	$0.00	6.30%
Paradigm Biocapital Advisors LP	2.05M	Mar 31, 2026	3.46%	$1.61	0.00%
Bvf Inc	1.98M	Mar 31, 2026	3.32%	$2.41	-7.12%
Vanguard Group Inc	1.57M	Dec 31, 2025	2.64%	$0.00	3.46%
Caligan Partners LP	1.28M	Mar 31, 2026	2.15%	$3.25	35.24%
State Street Corp	1.22M	Mar 31, 2026	2.04%	$0.00	62.26%
Vanguard Capital Management, LLC	1.13M	Mar 31, 2026	1.89%	$0.00	0.00%
5AM Venture Management, LLC	1.03M	Mar 31, 2026	1.73%	$10.94	0.00%
T. Rowe Price Associates, Inc.	986.06K	Mar 31, 2026	1.66%	$0.00	6,732.46%
Logos Global Management LP	850.00K	Mar 31, 2026	1.43%	$1.63	304.76%
Barclays PLC	833.40K	Mar 31, 2026	1.40%	$0.01	992.14%
Canaan Partners XI LLC	750.00K	Jun 30, 2026	1.26%	$18.82	0.00%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Fidelity OTC	3.28M	5.51%	▲ 0.00%	May 31, 2026
2	State Street® SPDR® S&P® Biotech ETF	1.39M	2.33%	▼ 2.18%	Jun 30, 2026
3	Vanguard Total Stock Mkt Idx Inv	1.14M	1.91%	▲ 35.79%	Jun 30, 2026
4	iShares Russell 2000 ETF	949.84K	1.60%	▲ 0.60%	Jun 30, 2026
5	T. Rowe Price New Horizons	793.14K	1.33%	▲ 102.57%	Jun 30, 2026
6	US Small-Cap Growth II Equity Comp	793.14K	1.33%	▲ 258.11%	Jun 30, 2026
7	Fidelity Advisor Equity Growth I	678.60K	1.14%	▲ 0.00%	May 31, 2026
8	Fidelity VIP Growth Initial	630.80K	1.06%	▲ 0.00%	May 31, 2026
9	T. Rowe Price Integrated US SmCapGrEq	558.50K	0.94%	▲ 248.19%	Jun 30, 2026
10	T. Rowe Price Integrated US Sm Gr Eq	558.50K	0.94%	▲ 118.51%	Jun 30, 2026
Financial Highlights

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Market Cap: $1.85B
EBITDA: $-142.37M
Book Value: $4.83
Earnings/Share: $-2.21
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -23.64%
ROE (TTM): -36.87%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%
Valuation Metrics

Enterprise Value: $1.44B
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 59.47M
Shares Float: 30.92M
% Insiders: 286.00%
% Institutions: 11,174.40%
Short % Float: 30.87%
Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

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Download Financials (Excel)
Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$0.00
Cost of Goods Sold
adjust
$-546.00K
Gross Profit
subtotal
$-546.00K
SG&A
adjust
$-29.83M
R&D
adjust
$-102.93M
Operating Income
subtotal
$-132.76M
Other / Non-Operating Items
adjust
$12.82M
Net Income
subtotal
$-119.95M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "TYRA",
        "Type": "Common Stock",
        "Name": "Tyra Biosciences Inc",
        "Exchange": "NASDAQ",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00RCQD9D1",
        "ISIN": "US90240B1061",
        "LEI": null,
        "PrimaryTicker": "TYRA.US",
        "CUSIP": "90240B106",
        "CIK": "0001863127",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2021-09-15",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": null,
        "IsDelisted": false,
        "Description": "Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SN\u00c5P, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is FGFR3, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for intrahepatic cholangiocarcinoma; and TYRA-430 for the treatment of hepatocellular carcinoma. Tyra Biosciences, Inc. was incorporated in 2018 and is headquartered in Carlsbad, California.",
        "Address": "2656 State Street, Carlsbad, CA, United States, 92008",
        "AddressData": {
            "Street": "2656 State Street",
            "City": "Carlsbad",
            "State": "CA",
            "Country": "United States",
            "ZIP": "92008"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Dr. Todd  Harris Ph.D.",
                "Title": "Co-Founder, CEO, President & Director",
                "YearBorn": "1979"
            },
            {
                "Name": "Mr. Bhavesh  Ashar M.B.A.",
                "Title": "Chief Operating Officer",
                "YearBorn": "1969"
            },
            {
                "Name": "Dr. Douglas  Warner M.D.",
                "Title": "Chief Medical Officer",
                "YearBorn": "1972"
            },
            {
                "Name": "Mr. Daniel  Bensen",
                "Title": "Co-Founder & Chief Discovery Officer",
                "YearBorn": "1975"
            },
            {
                "Name": "Ms. Julia  Rueb",
                "Title": "VP of Finance & Principal Accounting Officer",
                "YearBorn": "1986"
            },
            {
                "Name": "Dr. Robert L. Hudkins Ph.D.",
                "Title": "Chief Technology Officer",
                "YearBorn": "1955"
            },
            {
                "Name": "Dr. Ronald V. Swanson Ph.D.",
                "Title": "Chief Scientific Officer",
                "YearBorn": "1963"
            },
            {
                "Name": "Mr. Ali D. Fawaz J.D.",
                "Title": "General Counsel & Secretary",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Sarah  Honig",
                "Title": "Senior VP of Corporate Development & Strategy",
                "YearBorn": "NA"
            },
            {
                "Name": "Liz  Pagano",
                "Title": "Chief Human Resources Officer",
                "YearBorn": "NA"
            }
        ],
        "Phone": "619 728 4760",
        "WebURL": "https://tyra.bio",
        "LogoURL": "/img/logos/US/TYRA.png",
        "FullTimeEmployees": 87,
        "UpdatedAt": "2026-07-28"
    },
    "Highlights": {
        "MarketCapitalization": 1847149952,
        "MarketCapitalizationMln": 1847.15,
        "EBITDA": -142368992,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 51.9683,
        "BookValue": 4.826,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -2.21,
        "EPSEstimateCurrentYear": -2.5665,
        "EPSEstimateNextYear": -2.8556,
        "EPSEstimateNextQuarter": -0.5743,
        "EPSEstimateCurrentQuarter": -0.5893,
        "MostRecentQuarter": "2026-03-31",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.2364,
        "ReturnOnEquityTTM": -0.3687,
        "RevenueTTM": 0,
        "RevenuePerShareTTM": 0,
        "QuarterlyRevenueGrowthYOY": 0,
        "GrossProfitTTM": 0,
        "DilutedEpsTTM": -2.21,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 0,
        "PriceBookMRQ": 4.7108,
        "EnterpriseValue": 1443814770,
        "EnterpriseValueRevenue": 0,
        "EnterpriseValueEbitda": -6.9506
    },
    "SharesStats": {
        "SharesOutstanding": 59470381,
        "SharesFloat": 30921625,
        "PercentInsiders": 2.86,
        "PercentInstitutions": 111.744,
        "SharesShort": null,
        "SharesShortPriorMonth": null,
        "ShortRatio": null,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.3087
    },
    "Technicals": {
        "Beta": 0.764,
        "52WeekHigh": 40.65,
        "52WeekLow": 9.96,
        "50DayMA": 31.0499,
        "200DayMA": 28.4256,
        "SharesShort": 9930770,
        "SharesShortPriorMonth": 11924900,
        "ShortRatio": 10.26,
        "ShortPercent": 0.3087
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.75,
        "TargetPrice": 51.9683,
        "StrongBuy": 6,
        "Buy": 2,
        "Hold": 0,
        "Sell": 0,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
            {
                "name": "RA Capital Management, LLC",
                "date": "2026-03-31",
                "totalShares": 20.5121,
                "totalAssets": 4.9504,
                "currentShares": 12198625,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "FMR Inc",
                "date": "2026-03-31",
                "totalShares": 13.0277,
                "totalAssets": 0.0156,
                "currentShares": 7747648,
                "change": 7735085,
                "change_p": 61570.3654
            },
            {
                "name": "Nextech Invest, Ltd.",
                "date": "2026-03-31",
                "totalShares": 6.82,
                "totalAssets": 10.9313,
                "currentShares": 4055861,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "HHG PLC",
                "date": "2026-03-31",
                "totalShares": 6.5421,
                "totalAssets": 0.0711,
                "currentShares": 3890589,
                "change": 955147,
                "change_p": 32.5384
            },
            {
                "name": "Alta Partners Management Company, L.P.",
                "date": "2026-06-30",
                "totalShares": 6.4291,
                "totalAssets": 95.9188,
                "currentShares": 3823425,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Farallon Capital Management, L.L.C.",
                "date": "2026-03-31",
                "totalShares": 6.0212,
                "totalAssets": 0.7818,
                "currentShares": 3580818,
                "change": 1514000,
                "change_p": 73.2527
            },
            {
                "name": "TCG Crossover Management, LLC",
                "date": "2026-03-31",
                "totalShares": 5.4632,
                "totalAssets": 3.56,
                "currentShares": 3248980,
                "change": 350877,
                "change_p": 12.1071
            },
            {
                "name": "COMMODORE CAPITAL LP",
                "date": "2026-03-31",
                "totalShares": 4.1617,
                "totalAssets": 5.4842,
                "currentShares": 2475000,
                "change": -900000,
                "change_p": -26.6667
            },
            {
                "name": "BlackRock Inc",
                "date": "2026-03-31",
                "totalShares": 3.7295,
                "totalAssets": 0.0015,
                "currentShares": 2217929,
                "change": 131506,
                "change_p": 6.3029
            },
            {
                "name": "Paradigm Biocapital Advisors LP",
                "date": "2026-03-31",
                "totalShares": 3.4555,
                "totalAssets": 1.6081,
                "currentShares": 2054991,
                "change": 2054991,
                "change_p": 0
            },
            {
                "name": "Bvf Inc",
                "date": "2026-03-31",
                "totalShares": 3.323,
                "totalAssets": 2.4112,
                "currentShares": 1976196,
                "change": -151469,
                "change_p": -7.119
            },
            {
                "name": "Vanguard Group Inc",
                "date": "2025-12-31",
                "totalShares": 2.6447,
                "totalAssets": 0.0006,
                "currentShares": 1572785,
                "change": 52600,
                "change_p": 3.4601
            },
            {
                "name": "Caligan Partners LP",
                "date": "2026-03-31",
                "totalShares": 2.1472,
                "totalAssets": 3.2545,
                "currentShares": 1276968,
                "change": 332711,
                "change_p": 35.2352
            },
            {
                "name": "State Street Corp",
                "date": "2026-03-31",
                "totalShares": 2.0448,
                "totalAssets": 0.0016,
                "currentShares": 1216078,
                "change": 466615,
                "change_p": 62.2599
            },
            {
                "name": "Vanguard Capital Management, LLC",
                "date": "2026-03-31",
                "totalShares": 1.8933,
                "totalAssets": 0.0011,
                "currentShares": 1125970,
                "change": 1125970,
                "change_p": 0
            },
            {
                "name": "5AM Venture Management, LLC",
                "date": "2026-03-31",
                "totalShares": 1.7308,
                "totalAssets": 10.9443,
                "currentShares": 1029298,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "T. Rowe Price Associates, Inc.",
                "date": "2026-03-31",
                "totalShares": 1.6581,
                "totalAssets": 0.0044,
                "currentShares": 986061,
                "change": 971629,
                "change_p": 6732.4626
            },
            {
                "name": "Logos Global Management LP",
                "date": "2026-03-31",
                "totalShares": 1.4293,
                "totalAssets": 1.6254,
                "currentShares": 850000,
                "change": 640000,
                "change_p": 304.7619
            },
            {
                "name": "Barclays PLC",
                "date": "2026-03-31",
                "totalShares": 1.4014,
                "totalAssets": 0.0077,
                "currentShares": 833399,
                "change": 757090,
                "change_p": 992.1372
            },
            {
                "name": "Canaan Partners XI LLC",
                "date": "2026-06-30",
                "totalShares": 1.2611,
                "totalAssets": 18.8225,
                "currentShares": 750000,
                "change": 0,
                "change_p": 0
            }
        ],
        "Funds": [
            {
                "name": "Fidelity OTC",
                "date": "2026-05-31",
                "totalShares": 5.5142,
                "totalAssets": 0.2453,
                "currentShares": 3279300,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "State Street\u00ae SPDR\u00ae S&P\u00ae Biotech ETF",
                "date": "2026-06-30",
                "totalShares": 2.3326,
                "totalAssets": 0.4142,
                "currentShares": 1387226,
                "change": -30900,
                "change_p": -2.1789
            },
            {
                "name": "Vanguard Total Stock Mkt Idx Inv",
                "date": "2026-06-30",
                "totalShares": 1.9093,
                "totalAssets": 0.0016,
                "currentShares": 1135472,
                "change": 299300,
                "change_p": 35.7941
            },
            {
                "name": "iShares Russell 2000 ETF",
                "date": "2026-06-30",
                "totalShares": 1.5972,
                "totalAssets": 0.0364,
                "currentShares": 949844,
                "change": 5643,
                "change_p": 0.5976
            },
            {
                "name": "T. Rowe Price New Horizons",
                "date": "2026-06-30",
                "totalShares": 1.3337,
                "totalAssets": 0.172,
                "currentShares": 793140,
                "change": 401600,
                "change_p": 102.5693
            },
            {
                "name": "US Small-Cap Growth II Equity Comp",
                "date": "2026-06-30",
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                "totalAssets": 0.172,
                "currentShares": 793140,
                "change": 571658,
                "change_p": 258.1059
            },
            {
                "name": "Fidelity Advisor Equity Growth I",
                "date": "2026-05-31",
                "totalShares": 1.1411,
                "totalAssets": 0.167,
                "currentShares": 678600,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity VIP Growth Initial",
                "date": "2026-05-31",
                "totalShares": 1.0607,
                "totalAssets": 0.1668,
                "currentShares": 630800,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "T. Rowe Price Integrated US SmCapGrEq",
                "date": "2026-06-30",
                "totalShares": 0.9391,
                "totalAssets": 0.1815,
                "currentShares": 558500,
                "change": 398100,
                "change_p": 248.192
            },
            {
                "name": "T. Rowe Price Integrated US Sm Gr Eq",
                "date": "2026-06-30",
                "totalShares": 0.9391,
                "totalAssets": 0.1815,
                "currentShares": 558500,
                "change": 302900,
                "change_p": 118.5055
            },
            {
                "name": "Fidelity OTC Commingled Pool Class D",
                "date": "2026-05-31",
                "totalShares": 0.9312,
                "totalAssets": 0.2423,
                "currentShares": 553800,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Stock Selector Small Cap",
                "date": "2026-04-30",
                "totalShares": 0.6551,
                "totalAssets": 0.1956,
                "currentShares": 389600,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Small Cap Growth",
                "date": "2026-04-30",
                "totalShares": 0.6298,
                "totalAssets": 0.1545,
                "currentShares": 374540,
                "change": 43590,
                "change_p": 13.1712
            },
            {
                "name": "Fidelity Advisor Biotechnology I",
                "date": "2026-05-31",
                "totalShares": 0.5956,
                "totalAssets": 0.6221,
                "currentShares": 354200,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Janus Henderson US SMID Cap Growth",
                "date": "2026-03-31",
                "totalShares": 0.5907,
                "totalAssets": 0.2595,
                "currentShares": 351278,
                "change": 351278,
                "change_p": 0
            },
            {
                "name": "T. Rowe Price New Horizons Tr-A",
                "date": "2026-06-30",
                "totalShares": 0.5894,
                "totalAssets": 0.176,
                "currentShares": 350494,
                "change": 246669,
                "change_p": 237.5815
            },
            {
                "name": "Janus Henderson Hrzn Biotec E2 USD",
                "date": "2026-03-31",
                "totalShares": 0.5847,
                "totalAssets": 0.8388,
                "currentShares": 347750,
                "change": 347750,
                "change_p": 0
            },
            {
                "name": "Janus Henderson Triton D",
                "date": "2026-04-30",
                "totalShares": 0.5774,
                "totalAssets": 0.211,
                "currentShares": 343360,
                "change": -7918,
                "change_p": -2.2541
            },
            {
                "name": "Fidelity Growth Discovery",
                "date": "2026-05-31",
                "totalShares": 0.5746,
                "totalAssets": 0.1669,
                "currentShares": 341700,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Vanguard Institutional Extnd Mkt Idx Tr",
                "date": "2026-06-30",
                "totalShares": 0.5732,
                "totalAssets": 0.0107,
                "currentShares": 340900,
                "change": 75178,
                "change_p": 28.292
            }
        ]
    },
    "InsiderTransactions": [
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}
Tyra Biosciences Inc

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