Stock Fundamentals

Company Information

Company Name
Tango Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US87583X1090
CIK: 0001819133
CUSIP: 87583X109
Currency: USD
Full Time Employees: 137
Phone: 857 320 4900
Fiscal Year End: December
IPO Date: Sep 03, 2020
Description:

Tango Therapeutics, Inc., a precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need. The company develops methylthioadenosine -cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors, including TNG462, which is in Phase 1/2 clinical trial for treating pancreatic and lung cancer; and TNG456, a brain-penetrant PRMT5 inhibitor for the treatment of glioblastoma. It is developing TNG260, a co-repressor of repressor element-1 silencing transcription inhibitor to reverse the immune evasion effect of serine-threonine kinase (STK) 11 loss-of-function mutations to treat lung cancer. The company was founded in 2017 and is headquartered in Boston, Massachusetts.

Address:

201 Brookline Avenue, Boston, MA, United States, 02215

Directors & Officers

Name Title Year Born
Dr. Barbara L. Weber M.D. Founder & Executive Chair 1957
Dr. Malte Peters M.D. President, CEO & Director 1962
Ms. Daniella Beckman CPA Executive Officer 1979
Dr. Adam S. Crystal M.D., Ph.D. President of Research & Development 1977
Prof. Alan Ashworth FRS, Ph.D. Founder & Member of Scientific Advisory Board 1961
Dr. William G. Kaelin Jr., M.D. Founder & Member of Scientific Advisory Board 1958
Dr. Antoni Ribas M.D., Ph.D. Founder & Member of Scientific Advisory Board 1967
Mr. Matthew Gall M.B.A. Chief Financial Officer 1977
Mr. Jannik N. Andersen Ph.D. Chief Scientific Officer NA
Ms. Julie Fogarty Vice President of Legal & Corporate Secretary NA

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Apr 15, 2026 Adam Crystal N/A Sale 38.46K $25.00 $961.50K
Apr 01, 2026 Adam Crystal N/A Sale 27.00K $21.20 $572.40K
Mar 25, 2026 Adam Crystal N/A Sale 12.00K $20.11 $241.32K
Mar 05, 2026 Adam Crystal N/A Sale 20.25K $15.00 $303.77K
Feb 25, 2026 Adam Crystal N/A Sale 54.35K $12.77 $693.99K
Feb 03, 2026 Adam Crystal N/A Sale 18.45K $12.26 $226.22K
Feb 03, 2026 Barbara Weber N/A Sale 30.52K $12.26 $374.16K
Feb 03, 2026 Daniella Beckman N/A Sale 10.32K $12.26 $126.49K
Oct 23, 2025 Rock Ventures Iv L.P. Third N/A Sale 477.40K $10.15 $4.85M
Sep 25, 2025 Rock Ventures Iv L.P. Third N/A Sale 500.00K $8.02 $4.01M
Sep 16, 2025 Rock Ventures Iv L.P. Third N/A Sale 363.54K $7.04 $2.56M
Sep 08, 2025 Rock Ventures Iv L.P. Third N/A Sale 86.46K $7.04 $608.67K
Sep 05, 2025 Rock Ventures Iv L.P. Third N/A Sale 642.91K $7.00 $4.50M
Aug 22, 2025 Rock Ventures Iv L.P. Third N/A Sale 302.19K $7.00 $2.12M
Aug 19, 2025 Rock Ventures Iv L.P. Third N/A Sale 1.10M $7.01 $7.71M

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
RTW INVESTMENTS, LLC 13.30M Mar 31, 2026 9.20% $2.77 791.92%
Adage Capital Partners Gp LLC 12.81M Mar 31, 2026 8.86% $0.41 20.75%
Boxer Capital Management, LLC 10.88M Mar 31, 2026 7.52% $29.87 0.00%
TCG Crossover Management, LLC 10.53M Mar 31, 2026 7.28% $6.30 -17.48%
FMR Inc 9.91M Mar 31, 2026 6.85% $0.01 245.45%
Farallon Capital Management, L.L.C. 9.10M Mar 31, 2026 6.29% $1.08 -30.35%
BlackRock Inc 8.75M Mar 31, 2026 6.05% $0.00 2.43%
Woodline Partners LP 8.00M Mar 31, 2026 5.53% $0.63 -20.57%
Nextech Invest, Ltd. 7.27M Dec 31, 2025 5.02% $6.22 31.30%
Vanguard Group Inc 6.75M Dec 31, 2025 4.67% $0.00 33.63%
TRV GP IV, LLC 6.37M Mar 31, 2026 4.41% $49.96 -19.05%
Siren, L.L.C. 5.66M Mar 31, 2026 3.91% $3.28 -30.72%
Vanguard Capital Management, LLC 5.16M Mar 31, 2026 3.57% $0.00 0.00%
The Goldman Sachs Group Inc 5.08M Mar 31, 2026 3.51% $0.01 2.71%
State Street Corp 4.65M Mar 31, 2026 3.22% $0.00 -25.19%
Deerfield Management Co 4.15M Mar 31, 2026 2.87% $1.02 42.65%
Paradigm Biocapital Advisors LP 4.01M Mar 31, 2026 2.77% $1.71 0.00%
Holocene Advisors, LP 3.93M Mar 31, 2026 2.72% $0.20 0.00%
Balyasny Asset Management LLC 3.83M Mar 31, 2026 2.65% $0.10 -27.51%
Logos Global Management LP 3.00M Mar 31, 2026 2.07% $3.13 -28.57%

Shares Statistics

Shares Outstanding: 162.81M
Shares Float: 69.56M
% Insiders: 117.30%
% Institutions: 11,385.10%
Short % Float: 23.46%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard Total Stock Mkt Idx Inv 3.94M 2.73% ▲ 0.27% Apr 30, 2026
2 Fidelity Growth Compy Commingled Pl S 2.80M 1.94% ▲ 29.19% Apr 30, 2026
3 iShares Russell 2000 ETF 2.65M 1.83% ▲ 0.93% May 29, 2026
4 Fidelity Select Biotechnology 2.34M 1.62% ▼ 7.37% Apr 30, 2026
5 Fidelity Growth Company Fund 2.23M 1.54% ▲ 28.24% Apr 30, 2026
6 State Street® SPDR® S&P® Biotech ETF 2.18M 1.51% ▼ 0.61% May 31, 2026
7 FIAM Small Cap Core Composite 1.26M 0.87% ▲ 0.00% Dec 31, 2025
8 Vanguard Institutional Extnd Mkt Idx Tr 1.11M 0.77% ▲ 0.84% Apr 30, 2026
9 Fidelity Small Cap Index 1.09M 0.75% ▲ 4.63% Mar 31, 2026
10 iShares Russell 2000 Value ETF 960.85K 0.66% ▲ 0.00% May 29, 2026

Valuation Metrics

Enterprise Value: $4.69B
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $5.04B
EBITDA: $-115.41M
Book Value: $2.55
Earnings/Share: $-0.83
Profit Margin: -188.15%
Operating Margin: -206.22%
ROA (TTM): -20.69%
ROE (TTM): -38.42%
Revenue (TTM): $56.99M
Revenue/Share (TTM): $0.46
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -100.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 16.32x 0.01x 0.13x N/A -0.03x
2024-12-31 6.98x 0.01x 0.37x N/A -0.02x
2023-12-31 7.54x 0.01x 0.37x N/A -0.02x
2022-12-31 6.76x 0.01x 0.43x -37.66x -0.02x
2021-12-31 12.10x 0.00x 0.31x -50.87x -0.03x
2020-12-31 4.73x 0.02x 0.81x N/A -0.02x
2019-12-31 1.61x 0.08x 0.86x N/A -0.05x

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