Talphera Inc.

TLPH.US
Healthcare · Drug Manufacturers - Specialty & Generic
1.30
+0.04 (+3.17%)
USD · NASDAQ

Company Information

Company Name
Talphera Inc.
Sector
Healthcare
Industry
Drug Manufacturers - Specialty & Generic
Exchange
NASDAQ
ISIN: US00444T2096
CIK: 0001427925
CUSIP: 00444T209
Currency: USD
Full Time Employees: 12
Phone: 650 216 3500
Fiscal Year End: December
IPO Date: Feb 11, 2011
Description:

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate, Niyad, is a lyophilized formulation of nafamostat that acts as a regional anticoagulant for infusion into the extracorporeal circuit. It is also developing LTX-608, a lyophilized vial containing nafamostat for IV infusion for disseminated intravascular coagulation, acute respiratory distress syndrome, acute pancreatitis, and an anti-viral treatment; Fedsyra, an ephedrine pre-filled syringe for injection; and a phenylephrine pre-filled syringe for injection. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is headquartered in San Mateo, California.

Address:

1850 Gateway Drive, San Mateo, CA, United States, 94404

People

Directors & Officers

Name Title Year Born
Mr. Vincent J. Angotti CEO & Director 1968
Mr. Raffi Mark Asadorian Chief Financial Officer 1969
Dr. Shakil Aslam M.D. Chief Medical Officer 1965
Mr. Anil N. Dasu Chief Engineering Officer 1963

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Mar 13, 2026 Vincent J Angotti N/A Purchase 213.31K $0.59 $125.85K
Feb 12, 2026 Badri N Dasu N/A Purchase 35.00K $0.81 $28.35K
Feb 12, 2026 Raffi Asadorian N/A Purchase 45.00K $0.81 $36.45K
Feb 12, 2026 Shakil Aslam N/A Purchase 35.00K $0.81 $28.35K
Feb 12, 2026 Vincent J Angotti N/A Purchase 105.36K $0.81 $85.34K

Shareholders

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
AIGH Capital Management, LLC 4.66M Mar 31, 2026 8.98% $0.47 0.00%
Rock Springs Capital Management LP 3.59M Mar 31, 2026 6.92% $0.16 0.00%
Nantahala Capital Management, LLC 3.49M Mar 31, 2026 6.73% $0.10 0.00%
Rosalind Advisors, Inc. 3.35M Mar 31, 2026 6.46% $1.01 -6.30%
Bleichroeder LP 1.31M Mar 31, 2026 2.52% $0.17 48.42%
CANTOR FITZGERALD, L. P. 887.48K Mar 31, 2026 1.71% $0.01 53.68%
Vanguard Group Inc 663.68K Dec 31, 2025 1.28% $0.00 131.87%
Empery Asset Management, LP 590.48K Mar 31, 2026 1.14% $0.53 -55.72%
Caption Management, LLC 561.82K Mar 31, 2026 1.08% $0.00 0.00%
Almitas Capital LLC 467.15K Mar 31, 2026 0.90% $0.08 0.00%
Vanguard Capital Management, LLC 441.61K Mar 31, 2026 0.85% $0.00 0.00%
Dauntless Investment Group, LLC 435.23K Mar 31, 2026 0.84% $0.22 -24.87%
Geode Capital Management, LLC 419.98K Mar 31, 2026 0.81% $0.00 22.45%
Shay Capital LLC 250.08K Mar 31, 2026 0.48% $0.02 0.00%
Renaissance Technologies Corp 237.76K Mar 31, 2026 0.46% $0.00 -7.62%
Vanguard Fiduciary Trust Co 192.41K Mar 31, 2026 0.37% $0.00 0.00%
Diadema Partners LP 153.56K Mar 31, 2026 0.30% $0.02 12.15%
Citadel Advisors Llc 106.15K Mar 31, 2026 0.20% $0.00 38.86%
Mariner Wealth Advisors LLC 100.00K Mar 31, 2026 0.19% $0.00 72.41%
GSA Capital Partners LLP 93.79K Mar 31, 2026 0.18% $0.00 347.18%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard Institutional Extnd Mkt Idx Tr 440.10K 0.85% ▲ 0.00% Jun 30, 2026
2 Vanguard Total Stock Mkt Idx Inv 261.77K 0.50% ▲ 0.00% Jun 30, 2026
3 Fidelity Extended Market Index 208.78K 0.40% ▲ 0.00% May 31, 2026
4 Fidelity Total Market Index 63.38K 0.12% ▲ 0.00% May 31, 2026
5 Fidelity Series Total Market Index 52.39K 0.10% ▲ 0.00% May 31, 2026
6 Spartan Extended Market Index Pool F 50.32K 0.10% ▲ 0.00% May 31, 2026
7 Northern Trust Extended Eq Market Idx 45.89K 0.09% ▲ 823.49% Mar 31, 2026
8 NT Ext Equity Mkt Index Fund - Lending 45.89K 0.09% ▲ 0.00% Jun 30, 2026
9 NT Ext Equity Mkt Index Fund - NL 41.05K 0.08% ▲ 0.00% Jun 30, 2026
10 NT Ext Equity Mkt Idx Fd - DC - NL - T2 29.78K 0.06% ▼ 7.41% Jun 30, 2026

Financial Highlights

Market Cap: $67.47M
EBITDA: $-15.16M
Book Value: $0.35
Earnings/Share: $-0.29
Profit Margin: 0.00%
Operating Margin: -1,451,600.00%
ROA (TTM): -40.19%
ROE (TTM): -118.40%
Revenue (TTM): $1.00K
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%

Valuation Metrics

Enterprise Value: $44.29M
Trailing P/E: 0.00
Forward P/E: 1.02

Shares Statistics

Shares Outstanding: 51.90M
Shares Float: 26.98M
% Insiders: 2,141.50%
% Institutions: 3,475.90%
Short % Float: 2.09%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

Open full waterfall
Line Item
Step Type
Value
Revenue
adjust
$28.00K
Gross Profit
subtotal
$28.00K
SG&A
adjust
$-7.48M
R&D
adjust
$-6.03M
Operating Income
subtotal
$-13.48M
Other / Non-Operating Items
adjust
$-806.00K
Net Income
subtotal
$-14.29M

Earnings Per Share (EPS) History

Financial Ratios

📦 Raw API Data (JSON Explorer)

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