Fundamentals - AlphaKey Financial

Stock Fundamentals

Directors & Officers

▼
Name	Title	Year Born
Mr. Michael G. Grey	Executive Chairman	1953
Dr. Javier Szwarcberg M.D., M.P.H.	CEO & Director	1970
Mr. Samir M. Gharib CPA, M.B.A.	President & CFO	1982
Dr. Kirk Ways M.D., Ph.D.	Chief Medical Officer & Director	1953
Mr. Bruno Gagnon BPHARM, M.Sc.	Senior Vice President of Clinical Development Operations	1969
Dr. Daven Mody Pharm.D.	Senior Vice President of Regulatory & Quality	NA
Mr. Corwin Dale Hooks	Chief Commercial Officer	1967
Insider Trading

▼
Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Oct 06, 2025	Parkman Healthcare Partners Ll	N/A	Purchase	256.00	$17.91	$4.58K
Oct 06, 2025	Parkman Healthcare Partners Ll	N/A	Sale	257.00	$19.14	$4.92K
Institutional Holders

▼
Holder Name	Shares	Date Reported	% Out	Value	% Change
Ikarian Capital, LLC	121.36K	Mar 31, 2026	8.84%	$0.64	0.00%
Millennium Management LLC	111.89K	Mar 31, 2026	8.15%	$0.00	0.00%
Citadel Advisors Llc	70.00K	Mar 31, 2026	5.10%	$0.00	0.00%
ADAR1 Capital Management LLC	58.60K	Mar 31, 2026	4.27%	$0.23	1.03%
Alyeska Investment Group, L.P.	51.67K	Mar 31, 2026	3.77%	$0.01	0.00%
Wellington Management Company LLP	48.80K	Mar 31, 2026	3.56%	$0.00	-17.22%
BOOTHBAY FUND MANAGEMENT, LLC	42.08K	Mar 31, 2026	3.07%	$0.04	-12.21%
Balyasny Asset Management LLC	40.00K	Mar 31, 2026	2.91%	$0.00	0.00%
The Carlyle Group Inc	38.62K	Mar 31, 2026	2.81%	$0.02	0.00%
Quinn Opportunity Partners LLC	26.81K	Mar 31, 2026	1.95%	$0.09	17.54%
ExodusPoint Capital Management, LP	22.00K	Mar 31, 2026	1.60%	$0.01	-12.94%
Vanguard Group Inc	17.87K	Dec 31, 2025	1.30%	$0.00	0.00%
BlackRock Inc	16.94K	Mar 31, 2026	1.23%	$0.00	0.00%
Geode Capital Management, LLC	12.89K	Mar 31, 2026	0.94%	$0.00	1.23%
StemPoint Capital LP	12.72K	Mar 31, 2026	0.93%	$0.08	0.00%
Squadron Capital Management LLC	12.20K	Mar 31, 2026	0.89%	$0.29	-82.57%
Diadema Partners LP	10.00K	Mar 31, 2026	0.73%	$0.11	0.00%
The Goldman Sachs Group Inc	5.51K	Mar 31, 2026	0.40%	$0.00	0.00%
State Street Corp	5.40K	Mar 31, 2026	0.39%	$0.00	-15.63%
Resolute Capital Asset Partners LLC	4.00K	Mar 31, 2026	0.29%	$0.14	0.00%
Shares Statistics

▼
Shares Outstanding: 2.75M
Shares Float: 2.65M
% Insiders: 351.30%
% Institutions: 3,106.40%
Short % Float: 7.90%
Fund Holdings

▼
Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard Total Stock Mkt Idx Inv	76.24K	5.56%	▲ 1,108.16%	Apr 30, 2026
2	Vanguard Institutional Extnd Mkt Idx Tr	11.91K	0.87%	▲ 0.00%	Apr 30, 2026
3	Fidelity Extended Market Index	5.99K	0.44%	▲ 5.39%	Mar 31, 2026
4	Wellington CIF Small Cap 2000	4.10K	0.30%	▲ 0.00%	Mar 31, 2026
5	Extended Equity Market Fund B	3.48K	0.25%	▲ 0.00%	Dec 31, 2025
6	Blackrock Extended Mkt Fund CF	3.48K	0.25%	▲ 0.00%	Apr 30, 2026
7	Extended Equity Market Fund E	3.48K	0.25%	▲ 0.00%	Dec 31, 2025
8	BlackRock Extended Equity Market Fund K	2.96K	0.22%	▼ 0.74%	Mar 31, 2026
9	Wellington CIF II Small Cap 2000	2.75K	0.20%	▲ 0.00%	Mar 31, 2026
10	Wellington CIF Biotechnology	2.40K	0.18%	▲ 0.00%	Dec 31, 2025
Valuation Metrics

▼
Enterprise Value: $93.38M
Trailing P/E: 0.00
Forward P/E: 0.00
Financial Highlights

▼
Market Cap: $135.69M
EBITDA: $-25.84M
Book Value: $30.99
Earnings/Share: $-35.82
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -37.16%
ROE (TTM): -148.85%
Revenue (TTM): $697.00K
Revenue/Share (TTM): $1.20
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -75.90%
Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

▼
Financial Ratios

▼
Balance Sheet (Yearly)

▼
Date	Cash	Total Debt	Total Assets	Total Liabilities	Total Equity
2025-12-31	$48.91M	$N/A	$53.02M	$10.51M	$42.52M
2024-12-31	$38.75M	$N/A	$45.21M	$16.39M	$28.82M
2023-12-31	$96.34M	$N/A	$103.95M	$27.44M	$76.51M
2022-12-31	$24.49M	$N/A	$85.65M	$17.16M	$68.49M
2021-12-31	$42.75M	$N/A	$126.49M	$15.12M	$111.37M
2020-12-31	$157.15M	$N/A	$162.88M	$13.46M	$149.43M
2019-12-31	$3.92M	$N/A	$4.69M	$35.33M	$-30.64M
2018-12-31	$4.11M	$N/A	$4.78M	$22.58M	$-17.80M
Financial Ratios

▼
Date	Current Ratio	Debt/Equity	Debt/Assets	Interest Coverage	Debt/EBITDA
2025-12-31	5.17x	0.01x	0.20x	-405.70x	-0.01x
2024-12-31	2.90x	0.07x	0.36x	-182.90x	-0.04x
2023-12-31	4.18x	0.05x	0.26x	-107.65x	-0.08x
2022-12-31	6.72x	0.07x	0.20x	-112.58x	-0.11x
2021-12-31	10.36x	0.05x	0.12x	-121.93x	-0.13x
2020-12-31	16.43x	0.03x	0.08x	-91.07x	-0.16x
2019-12-31	1.08x	-0.15x	7.53x	-201.65x	-0.34x
2018-12-31	1.76x	0.00x	4.73x	N/A	0.00x
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "SPRB",
        "Type": "Common Stock",
        "Name": "Spruce Biosciences, Inc. Common Stock",
        "Exchange": "NASDAQ",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00HYZ1522",
        "ISIN": "US85209E1091",
        "LEI": null,
        "PrimaryTicker": "SPRB.US",
        "CUSIP": "85209E109",
        "CIK": "0001683553",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2020-10-09",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": null,
        "IsDelisted": false,
        "Description": "Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize Tildacerfont for the treatment of CAH in Japan. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in South San Francisco, California.",
        "Address": "611 Gateway Boulevard, South San Francisco, CA, United States, 94080",
        "AddressData": {
            "Street": "611 Gateway Boulevard",
            "City": "South San Francisco",
            "State": "CA",
            "Country": "United States",
            "ZIP": "94080"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Michael G. Grey",
                "Title": "Executive Chairman",
                "YearBorn": "1953"
            },
            {
                "Name": "Dr. Javier  Szwarcberg M.D., M.P.H.",
                "Title": "CEO & Director",
                "YearBorn": "1970"
            },
            {
                "Name": "Mr. Samir M. Gharib CPA, M.B.A.",
                "Title": "President & CFO",
                "YearBorn": "1982"
            },
            {
                "Name": "Dr. Kirk  Ways M.D., Ph.D.",
                "Title": "Chief Medical Officer & Director",
                "YearBorn": "1953"
            },
            {
                "Name": "Mr. Bruno  Gagnon BPHARM, M.Sc.",
                "Title": "Senior Vice President of Clinical Development Operations",
                "YearBorn": "1969"
            },
            {
                "Name": "Dr. Daven  Mody Pharm.D.",
                "Title": "Senior Vice President of Regulatory & Quality",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Corwin Dale Hooks",
                "Title": "Chief Commercial Officer",
                "YearBorn": "1967"
            }
        ],
        "Phone": "415 343 5986",
        "WebURL": "https://sprucebio.com",
        "LogoURL": "/img/logos/US/SPRB.png",
        "FullTimeEmployees": 8,
        "UpdatedAt": "2026-06-03"
    },
    "Highlights": {
        "MarketCapitalization": 135687296,
        "MarketCapitalizationMln": 135.6873,
        "EBITDA": -25841000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 158,
        "BookValue": 30.987,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -35.82,
        "EPSEstimateCurrentYear": -22.9575,
        "EPSEstimateNextYear": 1.8775,
        "EPSEstimateNextQuarter": -5.7225,
        "EPSEstimateCurrentQuarter": -6.115,
        "MostRecentQuarter": "2026-03-31",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.3716,
        "ReturnOnEquityTTM": -1.4885,
        "RevenueTTM": 697000,
        "RevenuePerShareTTM": 1.201,
        "QuarterlyRevenueGrowthYOY": -0.759,
        "GrossProfitTTM": -13622000,
        "DilutedEpsTTM": -35.82,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 49.1886,
        "PriceBookMRQ": 4.0504,
        "EnterpriseValue": 93380655,
        "EnterpriseValueRevenue": 77.3243,
        "EnterpriseValueEbitda": -0.2305
    },
    "SharesStats": {
        "SharesOutstanding": 2752278,
        "SharesFloat": 2651600,
        "PercentInsiders": 3.5130000000000003,
        "PercentInstitutions": 31.064000000000004,
        "SharesShort": null,
        "SharesShortPriorMonth": null,
        "ShortRatio": null,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.079
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    "Technicals": {
        "Beta": 3.308,
        "52WeekHigh": 240,
        "52WeekLow": 4.35,
        "50DayMA": 58.8335,
        "200DayMA": 69.1785,
        "SharesShort": 215061,
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        "ShortRatio": 2.68,
        "ShortPercent": 0.079
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "1:75",
        "LastSplitDate": "2025-08-07",
        "NumberDividendsByYear": []
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    "AnalystRatings": {
        "Rating": 3,
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        "StrongBuy": 0,
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        "Hold": 5,
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        "StrongSell": 0
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    "Holders": {
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                "date": "2026-03-31",
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                "name": "Millennium Management LLC",
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            },
            {
                "name": "Citadel Advisors Llc",
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                "name": "The Carlyle Group Inc",
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                "name": "Diadema Partners LP",
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            {
                "name": "The Goldman Sachs Group Inc",
                "date": "2026-03-31",
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                "name": "Vanguard Institutional Extnd Mkt Idx Tr",
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            },
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                "name": "NT Ext Equity Mkt Index Fund - Lending",
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                "name": "Dimensional US Small Cap ETF",
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            {
                "name": "Vanguard Instl Ttl Stk Mkt Idx InstlPls",
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                "currentShares": 1159,
                "change": 1159,
                "change_p": 0
            },
            {
                "name": "NT Ext Equity Mkt Index Fund - NL",
                "date": "2026-03-31",
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}
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