SNDX
Syndax Pharmaceuticals Inc

SNDX.US syndax.com
Healthcare · Biotechnology
18.18
-0.64 (-3.40%)
USD · NASDAQ
52-week range
12.99
25.59
Trading at 41% of the 52-week range
Market Cap
1.62B
P/E Ratio
0.00
Forward P/E
0.00
Book Value
0.17
Div. Yield
N/A
% Institutions
126.21%
% Insiders
1.69%
1 Year

+11.1%
3 Year

+5.1%
10 Year

+22.1%
Description
Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also developing revumenib for the treatment of R/R acute myeloid leukemia (AML) with a nucleophosmin 1 mutation (mNPM1) and in combination with standard-of-care agents in mNPM1 AML or KMT2Ar acute leukemia, as well as for metastatic colorectal cancer; axatilimab to treat idiopathic pulmonary fibrosis; and Entinostat, a Class 1 HDAC inhibitor. It has an agreement with Eddingpharm International Company Limited for licensing, development, and commercialization of Entinostat. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in New York, New York.
People

▼
Directors & Officers

Name	Title	Year Born
Mr. Michael A. Metzger M.B.A.	CEO & Director	1971
Mr. Keith Alan Goldan CPA	CFO, Treasurer & Principal Accounting Officer	1971
Mr. Luke J. Albrecht J.D.	Senior VP, General Counsel & Secretary	1979
Mr. Steven Closter	Chief Commercial Officer	1969
Dr. Nicholas A.J. Botwood B.Sc., MBBS	Head of Research & Development and Chief Medical Officer	1968
Dr. Peter Ordentlich B.Sc., Ph.D.	Co-Founder & Chief Scientific Officer	1969
Dr. Richard A. Heyman Ph.D.	Co-Founder	1957
Dr. Ronald M. Evans Ph.D.	Co-Founder, Advisor and Chair of Scientific Advisory Board	1950
Dr. Michael Downes Ph.D.	Co-Founder	NA
Sharon Klahre	Vice President of Investor Relations & Communications	NA
Insider Trading

Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Feb 09, 2026	Keith A Goldan	N/A	Sale	3.41K	$21.03	$71.71K
Feb 09, 2026	Michael A Metzger	N/A	Sale	17.16K	$21.03	$360.85K
Feb 06, 2026	Keith A Goldan	N/A	Sale	2.08K	$20.62	$42.93K
Feb 06, 2026	Michael A Metzger	N/A	Sale	7.41K	$20.62	$152.84K
Sep 08, 2025	Michael A Metzger	N/A	Sale	157.31K	$16.41	$2.58M
Aug 18, 2025	Dennis Podlesak	N/A	Sale	19.20K	$15.84	$304.13K
Aug 15, 2025	Dennis Podlesak	N/A	Sale	19.20K	$15.54	$298.37K
Jul 16, 2025	Keith A Goldan	N/A	Sale	1.30K	$9.29	$12.04K
Jul 16, 2025	Michael A Metzger	N/A	Sale	7.53K	$9.29	$69.99K
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
BlackRock Inc	8.25M	Mar 31, 2026	9.24%	$0.00	0.19%
Kynam Capital Management, LP	8.05M	Jun 30, 2026	9.02%	$9.73	0.00%
The Goldman Sachs Group Inc	5.00M	Mar 31, 2026	5.60%	$0.01	-12.27%
State Street Corp	4.43M	Mar 31, 2026	4.96%	$0.00	-3.62%
Bank of America Corp	4.25M	Mar 31, 2026	4.76%	$0.01	-9.78%
Vanguard Capital Management, LLC	3.82M	Mar 31, 2026	4.28%	$0.00	0.00%
Deerfield Management Co	3.78M	Mar 31, 2026	4.23%	$1.04	0.00%
Eversept Partners, LP	2.80M	Jun 30, 2026	3.13%	$3.17	-3.03%
Kingdon Capital Management LLC	2.50M	Jun 30, 2026	2.80%	$5.60	0.00%
StemPoint Capital LP	2.43M	Mar 31, 2026	2.72%	$5.48	81.54%
Hood River Capital Management LLC	2.35M	Mar 31, 2026	2.64%	$0.55	1.63%
Geode Capital Management, LLC	2.16M	Mar 31, 2026	2.42%	$0.00	3.16%
Franklin Templeton Inc	2.15M	Mar 31, 2026	2.41%	$0.01	-11.21%
Millennium Management LLC	2.05M	Jun 30, 2026	2.30%	$0.02	929.43%
Point72 Asset Management, L.P.	1.99M	Mar 31, 2026	2.22%	$0.06	-59.33%
Elmind Capital LP	1.86M	Mar 31, 2026	2.08%	$12.30	0.00%
Vanguard Portfolio Management, LLC	1.74M	Mar 31, 2026	1.95%	$0.00	0.00%
BNP Paribas Investment Partners SA	1.73M	Mar 31, 2026	1.94%	$0.05	25.94%
Soleus Capital Management, L.P.	1.63M	Jun 30, 2026	1.82%	$1.23	-5.73%
Two Sigma Investments LLC	1.58M	Mar 31, 2026	1.77%	$0.03	37.72%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	State Street® SPDR® S&P® Biotech ETF	3.71M	4.16%	▼ 1.06%	Aug 31, 2026
2	Vanguard MStar Total Stk Mkt Idx Invest	2.84M	3.18%	▲ 0.53%	Jul 31, 2026
3	iShares Russell 2000 ETF	2.28M	2.55%	▼ 0.57%	Aug 31, 2026
4	Hood River Small-Cap Growth Instl	1.21M	1.36%	▲ 0.00%	Jun 30, 2026
5	Franklin Biotechnology Discv A(acc)USD	1.08M	1.20%	▲ 5.50%	Jul 31, 2026
6	BNP Paribas US Small Cap ClassicC	1.07M	1.20%	▲ 6.25%	Jul 31, 2026
7	Franklin US Small Cap Growth Equity	1.04M	1.17%	▲ 79.63%	Jul 31, 2026
8	Vanguard Institutional Extnd Mkt Idx Tr	1.02M	1.14%	▲ 0.84%	Jul 31, 2026
9	Fidelity Small Cap Index	963.60K	1.08%	▲ 12.36%	Jun 30, 2026
10	Franklin Small Cap Growth Adv	928.03K	1.04%	▲ 59.62%	Jul 31, 2026
Financial Highlights

▼
Market Cap: $1.62B
EBITDA: $-194.16M
PEG Ratio: $0.00
Book Value: $0.17
Earnings/Share: $-2.51
Profit Margin: -87.52%
Operating Margin: -54.95%
ROA (TTM): -18.67%
ROE (TTM): -255.93%
Revenue (TTM): $252.25M
Revenue/Share (TTM): $2.87
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 91.80%
Valuation Metrics

Enterprise Value: $1.72B
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 89.30M
Shares Float: 80.30M
% Insiders: 1.69%
% Institutions: 126.21%
Short % Float: 24.70%
Stock Price History

▼
1 Year Price History

3 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Revenue, Net Income & Operating Cash Flow (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$172.35M
Cost of Goods Sold
adjust
$-6.97M
Gross Profit
subtotal
$165.38M
SG&A
adjust
$-179.68M
R&D
adjust
$-258.78M
Operating Income
subtotal
$-273.08M
Other / Non-Operating Items
adjust
$-12.34M
Net Income
subtotal
$-285.42M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
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    "General": {
        "Code": "SNDX",
        "Type": "Common Stock",
        "Name": "Syndax Pharmaceuticals Inc",
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}
Syndax Pharmaceuticals Inc

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