PTGX.US Fundamentals - AlphaKey Financial

People

▼
Directors & Officers

Name	Title	Year Born
Dr. Dinesh V. Patel Ph.D.	CEO, President, Secretary & Director	1957
Mr. Asif Ali	Executive VP & CFO	1974
Dr. Arturo M. Molina FACP, M.D., M.S.	Chief Medical Officer	1959
Mr. Venkat Thalladi Ph.D.	EVP & Chief Technical Officer	NA
Dr. Newman Yeilding M.D.	Executive VP, Chief Scientific Officer	NA
Mr. Matthew M. Gosling J.D.	Executive VP and Chief Legal & Business Officer	1971
Ms. Carena Spivey	Executive VP & Chief Human Resources Officer	NA
Dr. Ashok Bhandari Ph.D.	EVP & Chief Discovery Officer	1964
Mr. Carter J. King	Executive Vice President of Business Development	1971
Ms. Abha Bommireddi	Executive VP & Chief of Staff	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Apr 20, 2026	Asif Ali	N/A	Sale	1.75K	$105.47	$184.57K	SEC
Mar 26, 2026	Arturo Md Molina	N/A	Sale	15.00K	$104.79	$1.57M	SEC
Mar 26, 2026	Asif Ali	N/A	Sale	24.77K	$104.24	$2.58M	SEC
Mar 26, 2026	Harold E Selick	N/A	Sale	24.00K	$105.00	$2.52M	SEC
Mar 25, 2026	Dinesh V Ph D Patel	N/A	Sale	54.64K	$101.00	$5.52M	SEC
Mar 24, 2026	Dinesh V Ph D Patel	N/A	Sale	59.00	$101.00	$5.96K	SEC
Feb 17, 2026	Lewis T Williams	N/A	Sale	18.00K	$82.42	$1.48M	SEC
Feb 06, 2026	William D Waddill	N/A	Sale	20.00K	$83.68	$1.67M	SEC
Jan 27, 2026	Arturo Md Molina	N/A	Sale	5.00K	$82.00	$410.00K	SEC
Jan 27, 2026	Asif Ali	N/A	Sale	46.20K	$83.13	$3.84M	SEC
Jan 27, 2026	Dinesh V Ph D Patel	N/A	Sale	4.07K	$83.19	$338.42K	SEC
Jan 26, 2026	Dinesh V Ph D Patel	N/A	Sale	24.89K	$84.03	$2.09M	SEC
Jan 23, 2026	Arturo Md Molina	N/A	Sale	13.15K	$82.42	$1.08M	SEC
Jan 23, 2026	Dinesh V Ph D Patel	N/A	Sale	19.32K	$84.59	$1.63M	SEC
Jan 20, 2026	Arturo Md Molina	N/A	Sale	9.51K	$82.48	$784.71K	SEC
Jan 20, 2026	Asif Ali	N/A	Sale	8.59K	$82.48	$708.34K	SEC
Jan 20, 2026	Dinesh V Ph D Patel	N/A	Sale	34.44K	$82.48	$2.84M	SEC
Oct 10, 2025	William D Waddill	N/A	Sale	12.00K	$81.62	$979.44K	SEC
Sep 22, 2025	William D Waddill	N/A	Sale	4.00K	$64.25	$257.00K	SEC
Aug 27, 2025	William D Waddill	N/A	Sale	4.00K	$59.25	$237.00K	SEC
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
BlackRock Inc	10.31M	Jun 30, 2026	15.93%	$0.02	5.40%
Farallon Capital Management, L.L.C.	6.35M	Jun 30, 2026	9.81%	$3.59	0.00%
RTW INVESTMENTS, LLC	5.06M	Jun 30, 2026	7.82%	$5.30	0.04%
Vanguard Portfolio Management, LLC	3.63M	Jun 30, 2026	5.61%	$0.02	4.25%
Wellington Management Company LLP	3.42M	Jun 30, 2026	5.28%	$0.07	-5.08%
UBS Group AG	3.40M	Jun 30, 2026	5.25%	$0.05	-34.35%
State Street Corp	3.32M	Jun 30, 2026	5.13%	$0.01	6.57%
HHG PLC	2.89M	Mar 31, 2026	4.47%	$0.15	9.12%
Vanguard Capital Management, LLC	2.85M	Jun 30, 2026	4.41%	$0.01	1.69%
Johnson & Johnson	2.45M	Jun 30, 2026	3.79%	$37.59	0.00%
Amvescap Plc.	2.34M	Jun 30, 2026	3.62%	$0.02	8.13%
T. Rowe Price Associates, Inc.	2.15M	Jun 30, 2026	3.32%	$0.03	29.07%
Jupiter Topco LLC	2.13M	Jun 30, 2026	3.29%	$0.11	0.00%
Geode Capital Management, LLC	1.74M	Jun 30, 2026	2.69%	$0.01	4.30%
Woodline Partners LP	1.41M	Jun 30, 2026	2.19%	$0.54	0.00%
Bank of America Corp	1.32M	Jun 30, 2026	2.05%	$0.01	2.24%
Jennison Associates LLC	1.15M	Jun 30, 2026	1.78%	$0.08	7.43%
Perceptive Advisors LLC	981.88K	Jun 30, 2026	1.52%	$1.81	-20.23%
ADAR1 Capital Management LLC	960.86K	Jun 30, 2026	1.48%	$5.39	-3.35%
Morgan Stanley - Brokerage Accounts	905.99K	Jun 30, 2026	1.40%	$0.01	-11.02%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	iShares Core S&P Small-Cap ETF	3.85M	5.96%	▲ 0.02%	Sep 30, 2026
2	Vanguard MStar Total Stk Mkt Idx Invest	2.05M	3.17%	▲ 0.01%	Sep 30, 2026
3	iShares Russell 2000 ETF	1.59M	2.46%	▼ 0.93%	Sep 30, 2026
4	Vanguard Small Cap Index	1.46M	2.25%	▼ 1.63%	Sep 30, 2026
5	Vanguard Health Care Inv	1.38M	2.13%	▼ 11.40%	Jun 30, 2026
6	State Street® SPDR® S&P® Biotech ETF	1.02M	1.58%	▼ 1.87%	Sep 30, 2026
7	Vanguard MStar Small Cap Growth Indx Inv	811.16K	1.25%	▼ 4.48%	Sep 30, 2026
8	Invesco Discovery A	806.35K	1.25%	▼ 5.03%	Aug 31, 2026
9	Fidelity Small Cap Index	672.66K	1.04%	▲ 0.85%	Jul 31, 2026
10	Fidelity Select Biotechnology	607.71K	0.94%	▲ 0.00%	Aug 31, 2026
Financial Highlights

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Market Cap: $9.08B
EBITDA: $59.88M
P/E Ratio: $136.23
PEG Ratio: $0.00
Book Value: $13.01
Earnings/Share: $1.03
Profit Margin: 29.40%
Operating Margin: 74.37%
ROA (TTM): 4.55%
ROE (TTM): 10.99%
Revenue (TTM): $281.99M
Revenue/Share (TTM): $4.36
Earnings Growth (YOY): 351.30%
Revenue Growth (YOY): 3,749.20%
Valuation Metrics

Enterprise Value: $8.18B
Trailing P/E: 136.23
Forward P/E: 36.90
Shares Statistics

Shares Outstanding: 64.71M
Shares Float: 52.89M
% Insiders: 0.709%
% Institutions: 119.73%
Short % Float: 16.78%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

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Line Item
Step Type
Value
Revenue
adjust
$46.02M
Cost of Goods Sold
adjust
$-1.23M
Gross Profit
subtotal
$44.79M
SG&A
adjust
$-44.85M
R&D
adjust
$-159.29M
Operating Income
subtotal
$-158.13M
Other / Non-Operating Items
adjust
$27.98M
Net Income
subtotal
$-130.15M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

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Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "PTGX",
        "Type": "Common Stock",
        "Name": "Protagonist Therapeutics Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG002B63KM7",
        "ISIN": null,
        "LEI": null,
        "PrimaryTicker": "PTGX.US",
        "CUSIP": null,
        "CIK": "0001377121",
        "EmployerIdNumber": "98-0505495",
        "FiscalYearEnd": "December",
        "IPODate": "2016-08-11",
        "InternationalDomestic": "Domestic",
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": "Domestic",
        "IsDelisted": false,
        "Description": "Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.",
        "Address": "7707 Gateway Boulevard, Newark, CA, United States, 94560",
        "AddressData": {
            "Street": "7707 Gateway Boulevard",
            "City": "Newark",
            "State": "CA",
            "Country": "United States",
            "ZIP": "94560"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Dr. Dinesh V. Patel Ph.D.",
                "Title": "CEO, President, Secretary & Director",
                "YearBorn": "1957"
            },
            {
                "Name": "Mr. Asif  Ali",
                "Title": "Executive VP & CFO",
                "YearBorn": "1974"
            },
            {
                "Name": "Dr. Arturo M. Molina FACP, M.D., M.S.",
                "Title": "Chief Medical Officer",
                "YearBorn": "1959"
            },
            {
                "Name": "Mr. Venkat  Thalladi Ph.D.",
                "Title": "EVP & Chief Technical Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Newman  Yeilding M.D.",
                "Title": "Executive VP, Chief Scientific Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Matthew M. Gosling J.D.",
                "Title": "Executive VP and Chief Legal & Business Officer",
                "YearBorn": "1971"
            },
            {
                "Name": "Ms. Carena  Spivey",
                "Title": "Executive VP & Chief Human Resources Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Ashok  Bhandari Ph.D.",
                "Title": "EVP & Chief Discovery Officer",
                "YearBorn": "1964"
            },
            {
                "Name": "Mr. Carter J. King",
                "Title": "Executive Vice President of Business Development",
                "YearBorn": "1971"
            },
            {
                "Name": "Ms. Abha  Bommireddi",
                "Title": "Executive VP & Chief of Staff",
                "YearBorn": "NA"
            }
        ],
        "Phone": "510 474 0170",
        "WebURL": "https://www.protagonist-inc.com",
        "LogoURL": "/img/logos/US/PTGX.png",
        "FullTimeEmployees": 141,
        "UpdatedAt": "2026-10-27"
    },
    "Highlights": {
        "MarketCapitalization": 9079867392,
        "MarketCapitalizationMln": 9079.8674,
        "EBITDA": 59883000,
        "PERatio": 136.233,
        "PEGRatio": 0,
        "WallStreetTargetPrice": 178.5714,
        "BookValue": 13.012,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": 1.03,
        "EPSEstimateCurrentYear": 4.7671,
        "EPSEstimateNextYear": -0.0993,
        "EPSEstimateNextQuarter": 2.3628,
        "EPSEstimateCurrentQuarter": 1.9289,
        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": 0.294,
        "OperatingMarginTTM": 0.7437,
        "ReturnOnAssetsTTM": 0.0455,
        "ReturnOnEquityTTM": 0.1099,
        "RevenueTTM": 281992000,
        "RevenuePerShareTTM": 4.358,
        "QuarterlyRevenueGrowthYOY": 37.492,
        "GrossProfitTTM": 281992000,
        "DilutedEpsTTM": 1.03,
        "QuarterlyEarningsGrowthYOY": 3.513
    },
    "Valuation": {
        "TrailingPE": 136.233,
        "ForwardPE": 36.9004,
        "PriceSalesTTM": 32.199,
        "PriceBookMRQ": 10.6419,
        "EnterpriseValue": 8182266644,
        "EnterpriseValueRevenue": 29.016,
        "EnterpriseValueEbitda": 136.6376
    },
    "SharesStats": {
        "SharesOutstanding": 64708285,
        "SharesFloat": 52888670,
        "PercentInsiders": 0.709,
        "PercentInstitutions": 119.729,
        "SharesShort": null,
        "SharesShortPriorMonth": null,
        "ShortRatio": null,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.1678
    },
    "Technicals": {
        "Beta": 1.524,
        "52WeekHigh": 160.81,
        "52WeekLow": 75.44,
        "50DayMA": 143.912,
        "200DayMA": 115.3948,
        "SharesShort": 10297224,
        "SharesShortPriorMonth": 9345382,
        "ShortRatio": 13.63,
        "ShortPercent": 0.1678
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.7857,
        "TargetPrice": 178.5714,
        "StrongBuy": 11,
        "Buy": 3,
        "Hold": 0,
        "Sell": 0,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
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                "name": "BlackRock Inc",
                "date": "2026-06-30",
                "totalShares": 15.9297,
                "totalAssets": 0.0188,
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                "change": 528468,
                "change_p": 5.4039
            },
            {
                "name": "Farallon Capital Management, L.L.C.",
                "date": "2026-06-30",
                "totalShares": 9.8116,
                "totalAssets": 3.5904,
                "currentShares": 6348906,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "RTW INVESTMENTS, LLC",
                "date": "2026-06-30",
                "totalShares": 7.8215,
                "totalAssets": 5.2967,
                "currentShares": 5061175,
                "change": 2122,
                "change_p": 0.0419
            },
            {
                "name": "Vanguard Portfolio Management, LLC",
                "date": "2026-06-30",
                "totalShares": 5.6087,
                "totalAssets": 0.0201,
                "currentShares": 3629298,
                "change": 148087,
                "change_p": 4.2539
            },
            {
                "name": "Wellington Management Company LLP",
                "date": "2026-06-30",
                "totalShares": 5.2803,
                "totalAssets": 0.0722,
                "currentShares": 3416781,
                "change": -182863,
                "change_p": -5.08
            },
            {
                "name": "UBS Group AG",
                "date": "2026-06-30",
                "totalShares": 5.2531,
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                "currentShares": 3399221,
                "change": -1778575,
                "change_p": -34.35
            },
            {
                "name": "State Street Corp",
                "date": "2026-06-30",
                "totalShares": 5.1331,
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                "change": 204805,
                "change_p": 6.5711
            },
            {
                "name": "HHG PLC",
                "date": "2026-03-31",
                "totalShares": 4.4686,
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                "currentShares": 2891527,
                "change": 241546,
                "change_p": 9.115
            },
            {
                "name": "Vanguard Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 4.4096,
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                "currentShares": 2853394,
                "change": 47498,
                "change_p": 1.6928
            },
            {
                "name": "Johnson & Johnson",
                "date": "2026-06-30",
                "totalShares": 3.785,
                "totalAssets": 37.591,
                "currentShares": 2449183,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Amvescap Plc.",
                "date": "2026-06-30",
                "totalShares": 3.6173,
                "totalAssets": 0.0227,
                "currentShares": 2340667,
                "change": 175997,
                "change_p": 8.1304
            },
            {
                "name": "T. Rowe Price Associates, Inc.",
                "date": "2026-06-30",
                "totalShares": 3.3221,
                "totalAssets": 0.0264,
                "currentShares": 2149662,
                "change": 484165,
                "change_p": 29.0703
            },
            {
                "name": "Jupiter Topco LLC",
                "date": "2026-06-30",
                "totalShares": 3.2914,
                "totalAssets": 0.1064,
                "currentShares": 2129780,
                "change": 2129780,
                "change_p": 0
            },
            {
                "name": "Geode Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 2.6909,
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                "currentShares": 1741209,
                "change": 71838,
                "change_p": 4.3033
            },
            {
                "name": "Woodline Partners LP",
                "date": "2026-06-30",
                "totalShares": 2.1855,
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                "change": 0,
                "change_p": 0
            },
            {
                "name": "Bank of America Corp",
                "date": "2026-06-30",
                "totalShares": 2.0469,
                "totalAssets": 0.0105,
                "currentShares": 1324498,
                "change": 29064,
                "change_p": 2.2436
            },
            {
                "name": "Jennison Associates LLC",
                "date": "2026-06-30",
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                "change": 79670,
                "change_p": 7.4318
            },
            {
                "name": "Perceptive Advisors LLC",
                "date": "2026-06-30",
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                "currentShares": 981879,
                "change": -249000,
                "change_p": -20.2294
            },
            {
                "name": "ADAR1 Capital Management LLC",
                "date": "2026-06-30",
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                "totalAssets": 5.3901,
                "currentShares": 960863,
                "change": -33256,
                "change_p": -3.3453
            },
            {
                "name": "Morgan Stanley - Brokerage Accounts",
                "date": "2026-06-30",
                "totalShares": 1.4001,
                "totalAssets": 0.0059,
                "currentShares": 905992,
                "change": -112230,
                "change_p": -11.0222
            }
        ],
        "Funds": [
            {
                "name": "iShares Core S&P Small-Cap ETF",
                "date": "2026-09-30",
                "totalShares": 5.9573,
                "totalAssets": 0.5296,
                "currentShares": 3854840,
                "change": 804,
                "change_p": 0.0209
            },
            {
                "name": "Vanguard MStar Total Stk Mkt Idx Invest",
                "date": "2026-09-30",
                "totalShares": 3.1673,
                "totalAssets": 0.0124,
                "currentShares": 2049500,
                "change": 152,
                "change_p": 0.0074
            },
            {
                "name": "iShares Russell 2000 ETF",
                "date": "2026-09-30",
                "totalShares": 2.4636,
                "totalAssets": 0.2911,
                "currentShares": 1594175,
                "change": -14916,
                "change_p": -0.927
            },
            {
                "name": "Vanguard Small Cap Index",
                "date": "2026-09-30",
                "totalShares": 2.2499,
                "totalAssets": 0.1153,
                "currentShares": 1455881,
                "change": -24099,
                "change_p": -1.6283
            },
            {
                "name": "Vanguard Health Care Inv",
                "date": "2026-06-30",
                "totalShares": 2.1333,
                "totalAssets": 0.4352,
                "currentShares": 1380445,
                "change": -177650,
                "change_p": -11.4017
            },
            {
                "name": "State Street\u00ae SPDR\u00ae S&P\u00ae Biotech ETF",
                "date": "2026-09-30",
                "totalShares": 1.5765,
                "totalAssets": 1.3874,
                "currentShares": 1020148,
                "change": -19400,
                "change_p": -1.8662
            },
            {
                "name": "Vanguard MStar Small Cap Growth Indx Inv",
                "date": "2026-09-30",
                "totalShares": 1.2536,
                "totalAssets": 0.2602,
                "currentShares": 811164,
                "change": -38088,
                "change_p": -4.4849
            },
            {
                "name": "Invesco Discovery A",
                "date": "2026-08-31",
                "totalShares": 1.2461,
                "totalAssets": 1.607,
                "currentShares": 806349,
                "change": -42722,
                "change_p": -5.0316
            },
            {
                "name": "Fidelity Small Cap Index",
                "date": "2026-07-31",
                "totalShares": 1.0395,
                "totalAssets": 0.2698,
                "currentShares": 672659,
                "change": 5659,
                "change_p": 0.8484
            },
            {
                "name": "Fidelity Select Biotechnology",
                "date": "2026-08-31",
                "totalShares": 0.9392,
                "totalAssets": 1.428,
                "currentShares": 607713,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "iShares S&P Small-Cap 600 Growth ETF",
                "date": "2026-09-30",
                "totalShares": 0.9263,
                "totalAssets": 1.1079,
                "currentShares": 599423,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "State Street SPDR Port S&P 600 Sm CpETF",
                "date": "2026-09-30",
                "totalShares": 0.9105,
                "totalAssets": 0.5296,
                "currentShares": 589194,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "iShares Russell 2000 Growth ETF",
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}
Protagonist Therapeutics Inc

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