Stock Fundamentals

Company Information

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Company Name
Madrigal Pharmaceuticals Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US5588681057
CIK: 0001157601
CUSIP: 87162T206
Currency: USD
Full Time Employees: 915
Phone: 267-824-2827
Website: https://www.madrigalpharma.com
Fiscal Year End: December
IPO Date: Feb 06, 2007
Description:

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.

Address:

Four Tower Bridge, West Conshohocken, PA, United States, 19428

Directors & Officers

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Name Title Year Born
Mr. William J. Sibold CEO, President & Director 1966
Dr. Rebecca A. Taub M.D. Founder, Senior Scientific & Medical Advisor and Director 1952
Ms. Mardi C. Dier Executive VP & CFO 1964
Ms. Shannon Kelley Executive VP, Chief Legal Officer & Corporate Secretary 1975
Ms. Carole Huntsman Executive VP & Chief Commercial Officer 1965
Mr. Mark Underwood Executive Vice President of Business Planning & Operations NA
Ms. Rita Thakkar Senior VP & Chief Accounting Officer 1974
Mr. Ronald Filippo Executive VP & Chief Information Officer NA
Ms. Tina E. Ventura Chief Investor Relations Officer NA
Mr. Clint Wallace Executive VP & Chief Human Resources Officer NA

Institutional Holders

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Holder Name Shares Date Reported % Out Value % Change
Baker Bros Advisors LP 2.14M Dec 31, 2025 9.43% $7.30 0.00%
RTW INVESTMENTS, LLC 1.99M Dec 31, 2025 8.78% $11.63 0.00%
HHG PLC 1.84M Sep 30, 2025 8.11% $0.39 -15.93%
venBio Select Advisor LLC 1.83M Sep 30, 2025 8.07% $10.87 -2.24%
Vanguard Group Inc 1.81M Dec 31, 2025 7.96% $0.02 -0.17%
Paulson & Company Inc 1.71M Dec 31, 2025 7.52% $30.48 -10.48%
BlackRock Inc 1.56M Sep 30, 2025 6.87% $0.01 8.41%
State Street Corp 658.10K Sep 30, 2025 2.90% $0.01 -4.72%
Wellington Management Company LLP 461.40K Dec 31, 2025 2.03% $0.05 14.08%
Geode Capital Management, LLC 446.23K Sep 30, 2025 1.96% $0.01 7.68%
FMR Inc 439.40K Dec 31, 2025 1.93% $0.01 9.54%
The Goldman Sachs Group Inc 386.10K Sep 30, 2025 1.70% $0.02 103.38%
William Blair Investment Management, LLC 354.22K Dec 31, 2025 1.56% $0.58 -13.98%
T. Rowe Price Associates, Inc. 352.52K Sep 30, 2025 1.55% $0.02 -30.67%
Amvescap Plc. 299.57K Sep 30, 2025 1.32% $0.02 49.52%
Armistice Capital, LLC 265.71K Dec 31, 2025 1.17% $1.84 121.45%
Polar Capital Holdings PLC 265.15K Sep 30, 2025 1.17% $0.59 17.63%
Morgan Stanley - Brokerage Accounts 249.65K Sep 30, 2025 1.10% $0.01 0.68%
Hood River Capital Management LLC 247.56K Dec 31, 2025 1.09% $1.58 1.96%
Lord, Abbett & Co LLC 244.80K Dec 31, 2025 1.08% $0.44 139.66%

Shares Statistics

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Shares Outstanding: 22.71M
Shares Float: 12.48M
% Insiders: 785.80%
% Institutions: 10,407.50%
Short % Float: 18.41%

🏆 Top 10 Institutional Holders

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Rank Holder Name Shares Held % of Shares Change Date Reported
1 Baker Bros Advisors LP 2.14M 9.43% ▲ 0.00% Dec 31, 2025
2 RTW INVESTMENTS, LLC 1.99M 8.78% ▲ 0.00% Dec 31, 2025
3 HHG PLC 1.84M 8.11% ▼ 15.93% Sep 30, 2025
4 venBio Select Advisor LLC 1.83M 8.07% ▼ 2.24% Sep 30, 2025
5 Vanguard Group Inc 1.81M 7.96% ▼ 0.17% Dec 31, 2025
6 Paulson & Company Inc 1.71M 7.52% ▼ 10.48% Dec 31, 2025
7 BlackRock Inc 1.56M 6.87% ▲ 8.41% Sep 30, 2025
8 State Street Corp 658.10K 2.90% ▼ 4.72% Sep 30, 2025
9 Wellington Management Company LLP 461.40K 2.03% ▲ 14.08% Dec 31, 2025
10 Geode Capital Management, LLC 446.23K 1.96% ▲ 7.68% Sep 30, 2025

Valuation Metrics

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Enterprise Value: $9.06B
Trailing P/E: 0.00
Forward P/E: 666.67

Financial Highlights

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Market Cap: $9.81B
EBITDA: $-298.59M
PEG Ratio: $0.00
Book Value: $26.39
Earnings/Share: $-12.85
Profit Margin: -30.08%
Operating Margin: -18.57%
ROA (TTM): -16.30%
ROE (TTM): -42.49%
Revenue (TTM): $958.40M
Revenue/Share (TTM): $42.72
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 210.80%

Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

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Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

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Financial Ratios (Yearly)

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Financial Ratios (Quarterly)

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Earnings History

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Balance Sheet (Yearly)

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Financial Ratios

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Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 4.01x 0.00x 0.52x -13.45x 0.00x
2024-12-31 6.10x 0.16x 0.28x -33.94x -0.26x
2023-12-31 5.38x 0.29x 0.37x -29.93x -0.32x
2022-12-31 3.12x 0.25x 0.46x -74.06x -0.17x
2021-12-31 3.54x 0.00x 0.28x -232.93x 0.00x
2020-12-31 6.13x 0.00x 0.16x -47.74x 0.00x
2019-12-31 17.52x 0.00x 0.06x -8.62x 0.00x
2018-12-31 57.46x 0.00x 0.02x -5.30x 0.00x
2017-12-31 19.10x 0.00x 0.05x -57.46x 0.00x
2016-12-31 8.58x 0.00x 0.12x -21.67x 0.00x
2015-12-31 0.01x 0.97x 0.26x -2.99x -15.19x
2014-12-31 3.22x 0.79x 0.35x -37.99x -0.62x
2013-12-31 2.86x 0.19x 0.48x -33.25x -0.11x
2012-12-31 4.32x 0.17x 0.27x -33.04x -0.21x
2011-12-31 2.66x 1.13x 0.65x -23.32x -0.38x
2010-12-31 3.08x 0.01x 0.57x -64.85x -0.01x
2009-12-31 2.71x 0.05x 0.49x 258.14x 0.02x
2008-12-31 2.74x -0.07x 1.60x -191.63x -0.05x
2007-12-31 5.63x 0.10x 0.80x N/A -0.04x
2006-12-31 4.12x -1.33x 1.03x N/A -0.04x
2005-12-31 4.35x 0.04x 0.26x N/A -0.03x
2004-12-31 9.79x 0.00x 0.11x N/A -0.01x
2003-12-31 22.04x 0.00x 0.04x N/A 0.00x
2002-12-31 N/A N/A N/A N/A 0.00x
2001-12-31 N/A 0.00x 0.01x N/A 0.00x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Jan 26, 2026 Rebecca Taub N/A Sale 647.00 $492.42 $318.60K
Jan 26, 2026 Carole Huntsman N/A Sale 910.00 $493.78 $449.34K
Jan 26, 2026 William John Sibold N/A Sale 1.58K $492.42 $776.55K
Jan 20, 2026 Rebecca Taub N/A Sale 2.24K $490.77 $1.10M
Jan 20, 2026 Shannon T Kelley N/A Sale 692.00 $497.36 $344.17K
Jan 09, 2026 Paul A Friedman N/A Sale 280.00 $551.24 $154.35K
Jan 09, 2026 Paul A Friedman N/A Sale 24.52K $522.39 $12.81M
Jan 09, 2026 Rebecca Taub N/A Sale 240.00 $550.33 $132.08K
Jan 09, 2026 Rebecca Taub N/A Sale 18.41K $522.40 $9.62M
Dec 10, 2025 Rebecca Taub N/A Sale 18.65K $552.15 $10.30M
Dec 10, 2025 Paul A Friedman N/A Sale 24.80K $552.18 $13.69M
Dec 04, 2025 William John Sibold N/A Sale 2.40K $575.34 $1.38M
Dec 02, 2025 Mardi Dier N/A Sale 4.17K $578.34 $2.41M
Nov 21, 2025 Carole Huntsman N/A Sale 1.96K $553.11 $1.08M
Nov 13, 2025 Richard S Levy N/A Sale 8.50K $520.96 $4.43M
Nov 05, 2025 Kenneth Bate N/A Sale 16.58K $484.30 $8.03M
Sep 09, 2025 William John Sibold N/A Sale 7.28K $445.63 $3.24M
Aug 21, 2025 William John Sibold N/A Sale 7.62K $400.18 $3.05M
Aug 20, 2025 Bros. Advisors Lp Baker N/A Purchase 59.90K $385.16 $23.07M
Aug 18, 2025 Bros. Advisors Lp Baker N/A Purchase 37.16K $373.21 $13.87M

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