MDGL
Madrigal Pharmaceuticals Inc

MDGL.US madrigalpharma.com + Research + Basket
Healthcare · Biotechnology
CIK 0001157601
Employees 915
Phone 267 824 2827
Fiscal year end December
IPO Feb 06, 2007
Address 1001 Conshohocken State Road, West Conshohocken, PA, United States, 19428
431.70
+0.70 (+0.16%)
USD · NASDAQ
52-week range
399.00
615.00
Trading at 15% of the 52-week range
Market Cap
9.96B
P/E Ratio
0.00
Forward P/E
67.11
Book Value
22.68
Div. Yield
N/A
% Institutions
104.44%
% Insiders
5.83%
1 Year

+2.4%
3 Year

+242.2%
10 Year

+2,516.4%
Description
Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.
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People

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Directors & Officers

Name	Title	Year Born
Mr. William J. Sibold	CEO, President & Director	1966
Dr. Rebecca A. Taub M.D.	Founder, Senior Scientific & Medical Advisor and Director	1952
Ms. Mardi C. Dier	Executive VP & CFO	1964
Ms. Shannon Kelley	Executive VP, Chief Legal Officer & Corporate Secretary	1975
Ms. Carole Huntsman	Executive VP & Chief Commercial Officer	1965
Dr. David Soergel M.D.	Executive VP & Chief Medical Officer	1968
Mr. Mark Underwood	Executive Vice President of Business Planning & Operations	NA
Ms. Rita Thakkar	Senior VP & Chief Accounting Officer	1974
Mr. Ronald Filippo	Executive VP & Chief Information Officer	NA
Ms. Tina E. Ventura	Chief Investor Relations Officer	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Mar 06, 2026	Mardi Dier	N/A	Sale	1.98K	$430.87	$853.98K	SEC
Mar 06, 2026	Carole Huntsman	N/A	Sale	419.00	$431.94	$180.98K	SEC
Mar 06, 2026	William John Sibold	N/A	Sale	1.66K	$431.94	$718.32K	SEC
Mar 06, 2026	Rebecca Taub	N/A	Sale	491.00	$431.94	$212.08K	SEC
Mar 06, 2026	Shannon T Kelley	N/A	Sale	360.00	$431.94	$155.50K	SEC
Mar 02, 2026	Mardi Dier	N/A	Sale	1.18K	$427.21	$505.39K	SEC
Jan 26, 2026	Carole Huntsman	N/A	Sale	910.00	$493.78	$449.34K	SEC
Jan 26, 2026	Rebecca Taub	N/A	Sale	647.00	$492.42	$318.60K	SEC
Jan 26, 2026	William John Sibold	N/A	Sale	1.58K	$492.42	$776.55K	SEC
Jan 20, 2026	Rebecca Taub	N/A	Sale	2.24K	$490.77	$1.10M	SEC
Jan 20, 2026	Shannon T Kelley	N/A	Sale	692.00	$497.36	$344.17K	SEC
Jan 09, 2026	Paul A Friedman	N/A	Sale	24.52K	$522.39	$12.81M	SEC
Jan 09, 2026	Rebecca Taub	N/A	Sale	18.41K	$522.40	$9.62M	SEC
Jan 09, 2026	Rebecca Taub	N/A	Sale	240.00	$550.33	$132.08K	SEC
Jan 09, 2026	Paul A Friedman	N/A	Sale	280.00	$551.24	$154.35K	SEC
Dec 10, 2025	Paul A Friedman	N/A	Sale	24.80K	$552.18	$13.69M	SEC
Dec 10, 2025	Rebecca Taub	N/A	Sale	18.65K	$552.15	$10.30M	SEC
Dec 04, 2025	William John Sibold	N/A	Sale	2.40K	$575.34	$1.38M	SEC
Dec 02, 2025	Mardi Dier	N/A	Sale	4.17K	$578.34	$2.41M	SEC
Nov 21, 2025	Carole Huntsman	N/A	Sale	1.96K	$553.11	$1.08M	SEC
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
Baker Bros Advisors LP	2.14M	Jun 30, 2026	9.28%	$5.77	0.07%
HHG PLC	2.02M	Mar 31, 2026	8.74%	$0.50	27.37%
RTW INVESTMENTS, LLC	1.99M	Jun 30, 2026	8.63%	$9.14	0.00%
Jupiter Topco LLC	1.94M	Jun 30, 2026	8.38%	$0.42	0.00%
venBio Select Advisor LLC	1.83M	Jun 30, 2026	7.94%	$8.84	0.83%
Paulson & Company Inc	1.34M	Jun 30, 2026	5.80%	$27.94	-3.75%
BlackRock Inc	1.20M	Jun 30, 2026	5.20%	$0.01	-23.03%
Vanguard Capital Management, LLC	835.67K	Jun 30, 2026	3.62%	$0.01	1.03%
Wellington Management Company LLP	825.71K	Jun 30, 2026	3.57%	$0.08	18.81%
Vanguard Portfolio Management, LLC	781.73K	Jun 30, 2026	3.38%	$0.02	-7.06%
State Street Corp	527.06K	Jun 30, 2026	2.28%	$0.01	-13.53%
Citadel Advisors Llc	507.23K	Jun 30, 2026	2.20%	$0.03	11.76%
UBS Group AG	401.71K	Jun 30, 2026	1.74%	$0.03	241.07%
Geode Capital Management, LLC	374.88K	Jun 30, 2026	1.62%	$0.01	-17.77%
FMR Inc	356.20K	Jun 30, 2026	1.54%	$0.01	-30.39%
William Blair Investment Management, LLC	324.12K	Jun 30, 2026	1.40%	$0.52	-4.82%
Amvescap Plc.	301.44K	Jun 30, 2026	1.30%	$0.01	-8.52%
Armistice Capital, LLC	288.00K	Jun 30, 2026	1.25%	$1.89	8.85%
Lord, Abbett & Co LLC	281.50K	Jun 30, 2026	1.22%	$0.43	15.97%
Assenagon Asset Management SA	248.43K	Jun 30, 2026	1.08%	$0.08	1,449.48%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard MStar Total Stk Mkt Idx Invest	587.78K	2.54%	▲ 0.27%	Sep 30, 2026
2	Vanguard Health Care Inv	521.93K	2.26%	▲ 17.51%	Jun 30, 2026
3	Vanguard Small Cap Index	416.15K	1.80%	▼ 1.96%	Sep 30, 2026
4	Polar Capital Biotech S Inc	349.55K	1.51%	▲ 27.58%	Aug 31, 2026
5	Janus Henderson Forty S	338.60K	1.47%	▲ 0.00%	Aug 31, 2026
6	State Street® SPDR® S&P® Biotech ETF	272.06K	1.18%	▼ 1.88%	Sep 30, 2026
7	Janus Henderson Enterprise D	233.27K	1.01%	▲ 0.00%	Aug 31, 2026
8	Vanguard MStar Small Cap Growth Indx Inv	231.70K	1.00%	▼ 4.88%	Sep 30, 2026
9	Vanguard Explorer Inv	182.64K	0.79%	▲ 310.96%	Jun 30, 2026
10	First Trust NYSE Arca Biotech ETF	168.69K	0.73%	▲ 0.00%	Sep 30, 2026
Financial Highlights

▼
Market Cap: $9.96B
EBITDA: $-321.10M
PEG Ratio: $0.00
Book Value: $22.68
Earnings/Share: $-12.85
Profit Margin: -25.32%
Operating Margin: -15.46%
ROA (TTM): -17.84%
ROE (TTM): -53.31%
Revenue (TTM): $1.28B
Revenue/Share (TTM): $56.15
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 71.20%
Valuation Metrics

Enterprise Value: $9.47B
Trailing P/E: 0.00
Forward P/E: 67.11
Shares Statistics

Shares Outstanding: 23.10M
Shares Float: 13.72M
% Insiders: 5.83%
% Institutions: 104.44%
Shares Short: 2.19M
Shares Short (Prior Month): 2.40M
Short Ratio: 7.90
Short % Float: 11.17%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$958.40M
Cost of Goods Sold
adjust
$-56.15M
Gross Profit
subtotal
$902.26M
SG&A
adjust
$-813.83M
R&D
adjust
$-388.53M
Operating Income
subtotal
$-300.10M
Other / Non-Operating Items
adjust
$11.81M
Net Income
subtotal
$-288.28M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "MDGL",
        "Type": "Common Stock",
        "Name": "Madrigal Pharmaceuticals Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG000QS6NV8",
        "ISIN": null,
        "LEI": "549300CHIMT2EUSNJB60",
        "PrimaryTicker": "MDGL.US",
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        "CIK": "0001157601",
        "EmployerIdNumber": "04-3508648",
        "FiscalYearEnd": "December",
        "IPODate": "2007-02-06",
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        "Sector": "Healthcare",
        "Industry": "Biotechnology",
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        "Description": "Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.",
        "Address": "1001 Conshohocken State Road, West Conshohocken, PA, United States, 19428",
        "AddressData": {
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                "Name": "Mr. William J. Sibold",
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                "Name": "Dr. Rebecca A. Taub M.D.",
                "Title": "Founder, Senior Scientific & Medical Advisor and Director",
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                "Name": "Ms. Mardi C. Dier",
                "Title": "Executive VP & CFO",
                "YearBorn": "1964"
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            {
                "Name": "Ms. Shannon  Kelley",
                "Title": "Executive VP, Chief Legal Officer & Corporate Secretary",
                "YearBorn": "1975"
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                "Name": "Ms. Carole  Huntsman",
                "Title": "Executive VP & Chief Commercial Officer",
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            {
                "Name": "Dr. David  Soergel M.D.",
                "Title": "Executive VP & Chief Medical Officer",
                "YearBorn": "1968"
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            {
                "Name": "Mr. Mark  Underwood",
                "Title": "Executive Vice President of Business Planning & Operations",
                "YearBorn": "NA"
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                "Title": "Senior VP & Chief Accounting Officer",
                "YearBorn": "1974"
            },
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                "Name": "Mr. Ronald  Filippo",
                "Title": "Executive VP & Chief Information Officer",
                "YearBorn": "NA"
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                "Name": "Ms. Tina E. Ventura",
                "Title": "Chief Investor Relations Officer",
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        "Phone": "267 824 2827",
        "WebURL": "https://www.madrigalpharma.com",
        "LogoURL": "/img/logos/US/MDGL.png",
        "FullTimeEmployees": 915,
        "UpdatedAt": "2026-10-29"
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        "EPSEstimateCurrentYear": -6.4925,
        "EPSEstimateNextYear": 9.625,
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        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": -0.2532,
        "OperatingMarginTTM": -0.1546,
        "ReturnOnAssetsTTM": -0.1784,
        "ReturnOnEquityTTM": -0.5331,
        "RevenueTTM": 1283939968,
        "RevenuePerShareTTM": 56.147,
        "QuarterlyRevenueGrowthYOY": 0.712,
        "GrossProfitTTM": 1174515968,
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    "Valuation": {
        "TrailingPE": 0,
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    "SharesStats": {
        "SharesOutstanding": 23104126,
        "SharesFloat": 13723389,
        "PercentInsiders": 5.827,
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}
Madrigal Pharmaceuticals Inc

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