Stock Fundamentals

Company Information

Company Name
Design Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US25056L1035
CIK: 0001807120
CUSIP: 25056L103
Currency: USD
Full Time Employees: 54
Phone: 858 293 4900
Fiscal Year End: December
IPO Date: Mar 26, 2021
Description:

Design Therapeutics, Inc. a clinical-stage biopharmaceutical company, research, designs, develops, and commercializes small molecule therapeutic drugs for the treatment of genetic diseases in the United States. The company utilizes its GeneTAC platform to design and develop therapeutic candidates for inherited diseases caused by nucleotide repeat expansion. Its lead product candidates for potentially disease-modifying treatment comprises Friedreich Ataxia, a monogenic, autosomal recessive, progressive multi-system disease that affects organ systems dependent on mitochondrial function that brings to neurological, cardiac, and metabolic dysfunction; Myotonic Dystrophy Type-1, a dominantly-inherited, monogenic progressive neuromuscular disease affecting skeletal muscle, heart, brain, and other organs; Fuchs Endothelial Corneal Dystrophy, a genetic eye disease characterized by bilateral degeneration of corneal endothelial cells and progressive loss of vision; and Huntington's Disease, a dominantly inherited, monogenic neurodegenerative disease characterized by movement, cognitive, and psychiatric disorders. The company was incorporated in 2017 and is headquartered in Carlsbad, California.

Address:

6005 Hidden Valley Road, Carlsbad, CA, United States, 92011

Directors & Officers

Name Title Year Born
Mr. Pratik Shah Ph.D. Co-Founder, President, CEO, Principal Financial Officer & Executive Chairperson 1970
Dr. Sean Jeffries Ph.D. Chief Operating Officer 1980
Dr. Chris M. Storgard M.D. Chief Medical Officer 1966
Dr. Aseem Z. Ansari Ph.D. Co-Founder & Scientific Advisor NA
Ms. Julie D. Burgess CPA Chief Accounting Officer NA
Mr. Doane Chilcoat Ph.D. Chief Technology Officer NA
Mr. Mustapha Parekh General Counsel NA
Dr. Tadimeti S. Rao Ph.D. Chief Scientific Officer NA
Mr. Jim Kerr Chief of Manufacturing & Product Development NA
Dr. Chengzhi Zhang Ph.D. Chief Chemist NA

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Dec 18, 2024 Deepa Prasad N/A Sale 3.81K $6.27 $23.86K
Aug 09, 2024 Arsani William N/A Sale 814.87K $4.25 $3.46M
Mar 25, 2024 John P Schmid N/A Purchase 17.81K $3.74 $66.61K
Mar 22, 2024 John P Schmid N/A Purchase 9.16K $3.62 $33.14K
Sep 29, 2023 Rodney W Lappe N/A Purchase 21.00K $2.35 $49.35K
Aug 29, 2023 Deepa Prasad N/A Purchase 12.00K $2.31 $27.72K

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
SR ONE CAPITAL MANAGEMENT, LP 6.53M Dec 31, 2025 10.45% $8.67 0.00%
RA Capital Management, LLC 2.97M Mar 31, 2026 4.76% $0.34 103.44%
Point72 Asset Management, L.P. 2.72M Mar 31, 2026 4.36% $0.04 -49.32%
Baker Bros Advisors LP 2.59M Mar 31, 2026 4.14% $0.16 15.80%
BlackRock Inc 2.13M Mar 31, 2026 3.42% $0.00 0.78%
Logos Global Management LP 1.95M Mar 31, 2026 3.12% $1.04 -22.00%
Driehaus Capital Management LLC 1.74M Mar 31, 2026 2.79% $0.14 47.90%
Vanguard Group Inc 1.63M Dec 31, 2025 2.61% $0.00 12.97%
Vivo Capital, LLC 1.61M Mar 31, 2026 2.58% $1.43 0.00%
Almitas Capital LLC 1.53M Dec 31, 2025 2.45% $3.16 -50.00%
Vanguard Capital Management, LLC 1.35M Mar 31, 2026 2.16% $0.00 0.00%
Woodline Partners LP 961.50K Mar 31, 2026 1.54% $0.04 1.85%
Trails Edge Capital Partners, LP 852.01K Mar 31, 2026 1.36% $2.08 0.00%
FMR Inc 798.41K Mar 31, 2026 1.28% $0.00 3.52%
Kynam Capital Management, LP 784.61K Mar 31, 2026 1.26% $0.52 0.00%
Geode Capital Management, LLC 692.52K Mar 31, 2026 1.11% $0.00 1.90%
State Street Corp 659.58K Mar 31, 2026 1.06% $0.00 1.84%
Morgan Stanley - Brokerage Accounts 656.57K Mar 31, 2026 1.05% $0.00 -6.51%
Acadian Asset Management LLC 616.48K Mar 31, 2026 0.99% $0.01 2,343.06%
The Goldman Sachs Group Inc 504.72K Mar 31, 2026 0.81% $0.00 86.48%

Shares Statistics

Shares Outstanding: 62.46M
Shares Float: 32.16M
% Insiders: 3,193.10%
% Institutions: 6,208.60%
Short % Float: 8.23%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard Total Stock Mkt Idx Inv 984.78K 1.58% ▲ 0.00% Apr 30, 2026
2 iShares Russell 2000 ETF 588.29K 0.94% ▲ 0.94% May 29, 2026
3 Fidelity Select Biotechnology 534.93K 0.86% ▼ 13.28% Apr 30, 2026
4 Heptagon Driehaus US Micro Cap Eq C$ Acc 347.24K 0.56% ▲ 164.15% Apr 30, 2026
5 Vanguard Institutional Extnd Mkt Idx Tr 335.81K 0.54% ▲ 0.71% Apr 30, 2026
6 State St Russell Sm/Mid Cp® Indx SL Cl I 267.46K 0.43% ▲ 0.00% May 31, 2026
7 iShares Biotechnology ETF 236.08K 0.38% ▲ 1.95% May 29, 2026
8 Fidelity Small Cap Index 234.42K 0.38% ▲ 0.40% Mar 31, 2026
9 iShares Russell 2000 Value ETF 212.41K 0.34% ▲ 0.00% May 29, 2026
10 Fidelity Enhanced Small Cap Core ETF 199.21K 0.32% ▲ 0.25% May 29, 2026

Valuation Metrics

Enterprise Value: $466.00M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $685.15M
EBITDA: $-77.74M
Book Value: $3.49
Earnings/Share: $-1.20
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -20.93%
ROE (TTM): -31.26%
Revenue (TTM): $33.00K
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 17.14x 0.00x 0.06x N/A -0.01x
2024-12-31 29.31x 0.00x 0.04x N/A -0.02x
2023-12-31 29.58x 0.00x 0.04x N/A -0.01x
2022-12-31 31.10x 0.00x 0.04x -14.41x -0.01x
2021-12-31 72.96x 0.00x 0.02x -120.24x -0.01x
2020-12-31 15.55x 0.00x 1.31x N/A 0.00x
2019-12-31 0.02x -0.19x 41.47x N/A -0.36x

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