Fundamentals - AlphaKey Financial

Stock Fundamentals

Directors & Officers

▼
Name	Title	Year Born
Dr. Ryan J. Watts Ph.D.	Co-Founder, President, CEO & Director	1976
Dr. Alexander O. Schuth M.D., Ph.D.	Co-Founder, CFO, COO & Secretary	1973
Dr. Dana Andersen	Chief Technical and Manufacturing Officer	NA
Mr. Joe Lewcock Ph.D.	Chief Scientific Officer	NA
Mr. Chris Walsh J.D.	General Counsel	NA
Ms. Cindy Dunkle	Chief People Officer	NA
Ms. Katie Peng M.B.A.	Chief Commercial Officer	1971
Mr. Peter Chin M.D.	Acting Chief Medical Officer & Head of Development	1968
Insider Trading

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Date	Insider Name	Title	Transaction Type	Shares	Price	Value
Jan 06, 2026	Alexander O Schuth	N/A	Sale	17.22K	$16.50	$284.10K
Jan 06, 2026	Ryan J Watts	N/A	Sale	35.20K	$16.50	$580.77K
Aug 13, 2025	Carole Ho	N/A	Sale	806.00	$14.64	$11.80K
Aug 12, 2025	Alexander O Schuth	N/A	Sale	2.94K	$13.58	$39.88K
Aug 12, 2025	Carole Ho	N/A	Sale	2.94K	$13.58	$39.88K
Jul 09, 2025	Ryan J Watts	N/A	Sale	495.28K	$15.00	$7.43M
Institutional Holders

▼
Holder Name	Shares	Date Reported	% Out	Value	% Change
Vanguard Group Inc	13.06M	Dec 31, 2025	8.23%	$0.00	8.88%
BlackRock Inc	13.03M	Mar 31, 2026	8.21%	$0.00	2.51%
Baillie Gifford & Co Limited.	12.07M	Mar 31, 2026	7.60%	$0.24	-1.99%
T. Rowe Price Investment Management,Inc.	8.52M	Mar 31, 2026	5.37%	$0.11	0.22%
Temasek Holdings Ltd.	7.01M	Mar 31, 2026	4.42%	$0.44	0.00%
State Street Corp	6.27M	Mar 31, 2026	3.95%	$0.00	0.14%
NORGES BANK	5.12M	Dec 31, 2025	3.23%	$0.01	29.70%
FMR Inc	4.58M	Mar 31, 2026	2.88%	$0.00	-24.96%
UBS Asset Mgmt Americas Inc	4.43M	Mar 31, 2026	2.79%	$0.02	-11.06%
The Goldman Sachs Group Inc	4.41M	Mar 31, 2026	2.78%	$0.01	14.90%
Baker Bros Advisors LP	3.73M	Mar 31, 2026	2.35%	$0.41	0.00%
Geode Capital Management, LLC	3.73M	Mar 31, 2026	2.35%	$0.00	7.78%
Holocene Advisors, LP	3.20M	Mar 31, 2026	2.01%	$0.15	1.35%
AllianceBernstein L.P.	2.89M	Mar 31, 2026	1.82%	$0.02	-18.67%
Dimensional Fund Advisors, Inc.	2.69M	Mar 31, 2026	1.70%	$0.01	13.39%
UBS Group AG	2.57M	Mar 31, 2026	1.62%	$0.01	6.93%
Pictet Asset Manangement SA	2.56M	Mar 31, 2026	1.61%	$0.05	92.53%
Capital Research Global Investors	2.51M	Mar 31, 2026	1.58%	$0.01	-32.57%
T. Rowe Price Associates, Inc.	2.46M	Mar 31, 2026	1.55%	$0.01	-37.07%
Fisher Asset Management, LLC	2.44M	Mar 31, 2026	1.54%	$0.02	-5.89%
Shares Statistics

▼
Shares Outstanding: 158.71M
Shares Float: 144.27M
% Insiders: 913.10%
% Institutions: 9,958.20%
Short % Float: 9.33%
Fund Holdings

▼
Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Scottish Mortgage Ord	7.04M	4.44%	▲ 0.00%	Mar 31, 2026
2	Vanguard Total Stock Mkt Idx Inv	4.26M	2.68%	▲ 0.39%	Apr 30, 2026
3	iShares Russell 2000 ETF	3.34M	2.10%	▲ 0.85%	Apr 30, 2026
4	State Street® SPDR® S&P® Biotech ETF	3.16M	1.99%	▼ 0.71%	Apr 30, 2026
5	Vanguard Small Cap Index	3.11M	1.96%	▼ 0.14%	Apr 30, 2026
6	Vanguard US Growth Investor	3.04M	1.91%	▲ 0.00%	Mar 31, 2026
7	Baillie Gifford US Equity Growth	3.04M	1.91%	▲ 0.00%	Mar 31, 2026
8	T. Rowe Price Small-Cap Stock	2.33M	1.47%	▲ 7.11%	Mar 31, 2026
9	T. Rowe Price US Small-Cap Core Equity	2.33M	1.47%	▲ 6.95%	Mar 31, 2026
10	American Funds SMALLCAP World A	2.21M	1.39%	▼ 4.34%	Mar 31, 2026
Valuation Metrics

▼
Enterprise Value: $2.29B
Trailing P/E: 0.00
Forward P/E: 0.00
Financial Highlights

▼
Market Cap: $3.07B
EBITDA: $-531.76M
Book Value: $5.84
Earnings/Share: $-2.88
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -26.95%
ROE (TTM): -49.59%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -100.00%
Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

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Financial Ratios

▼
Balance Sheet (Yearly)

▼
Date	Cash	Total Debt	Total Assets	Total Liabilities	Total Equity
2025-12-31	$205.33M	$N/A	$1.14B	$131.09M	$1.01B
2024-12-31	$174.96M	$N/A	$1.37B	$144.50M	$1.23B
2023-12-31	$127.11M	$N/A	$1.15B	$122.96M	$1.03B
2022-12-31	$218.04M	$N/A	$1.46B	$417.81M	$1.04B
2021-12-31	$293.48M	$N/A	$1.40B	$441.87M	$962.29M
2020-12-31	$507.14M	$N/A	$1.60B	$453.75M	$1.15B
2019-12-31	$79.45M	$N/A	$553.23M	$158.34M	$394.89M
2018-12-31	$77.12M	$N/A	$661.98M	$115.14M	$546.85M
2017-12-31	$218.38M	$N/A	$486.72M	$20.93M	$465.80M
2016-12-31	$39.85M	$N/A	$271.07M	$16.55M	$254.52M
2015-12-31	$30.74M	$N/A	$36.68M	$52.32M	$-15.63M
Financial Ratios

▼
Date	Current Ratio	Debt/Equity	Debt/Assets	Interest Coverage	Debt/EBITDA
2025-12-31	9.16x	0.01x	0.11x	N/A	-0.02x
2024-12-31	8.46x	0.01x	0.11x	N/A	-0.02x
2023-12-31	13.65x	0.01x	0.11x	N/A	-0.04x
2022-12-31	3.77x	0.01x	0.29x	-23.06x	-0.02x
2021-12-31	2.37x	0.01x	0.31x	-22.43x	-0.02x
2020-12-31	20.86x	0.00x	0.28x	3.53x	0.07x
2019-12-31	9.48x	0.01x	0.29x	-14.01x	-0.02x
2018-12-31	14.67x	0.03x	0.17x	-23.72x	-0.49x
2017-12-31	28.92x	0.00x	0.04x	-46.11x	0.00x
2016-12-31	19.98x	0.00x	0.06x	N/A	0.00x
2015-12-31	9.60x	0.00x	1.43x	-153.02x	0.00x
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "DNLI",
        "Type": "Common Stock",
        "Name": "Denali Therapeutics Inc",
        "Exchange": "NASDAQ",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG008P7F869",
        "ISIN": "US24823R1059",
        "LEI": "549300ZTQ2HO18L3Q830",
        "PrimaryTicker": "DNLI.US",
        "CUSIP": "24823R105",
        "CIK": "0001714899",
        "EmployerIdNumber": "46-3872213",
        "FiscalYearEnd": "December",
        "IPODate": "2017-12-08",
        "InternationalDomestic": "Domestic",
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": "Domestic",
        "IsDelisted": false,
        "Description": "Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.",
        "Address": "161 Oyster Point Boulevard, South San Francisco, CA, United States, 94080",
        "AddressData": {
            "Street": "161 Oyster Point Boulevard",
            "City": "South San Francisco",
            "State": "CA",
            "Country": "United States",
            "ZIP": "94080"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Dr. Ryan J. Watts Ph.D.",
                "Title": "Co-Founder, President, CEO & Director",
                "YearBorn": "1976"
            },
            {
                "Name": "Dr. Alexander O. Schuth M.D., Ph.D.",
                "Title": "Co-Founder, CFO, COO & Secretary",
                "YearBorn": "1973"
            },
            {
                "Name": "Dr. Dana  Andersen",
                "Title": "Chief Technical and Manufacturing Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Joe  Lewcock Ph.D.",
                "Title": "Chief Scientific Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Chris  Walsh J.D.",
                "Title": "General Counsel",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Cindy  Dunkle",
                "Title": "Chief People Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Katie  Peng M.B.A.",
                "Title": "Chief Commercial Officer",
                "YearBorn": "1971"
            },
            {
                "Name": "Mr. Peter  Chin M.D.",
                "Title": "Acting Chief Medical Officer & Head of Development",
                "YearBorn": "1968"
            }
        ],
        "Phone": "650 866 8547",
        "WebURL": "https://www.denalitherapeutics.com",
        "LogoURL": "/img/logos/US/DNLI.png",
        "FullTimeEmployees": 507,
        "UpdatedAt": "2026-06-02"
    },
    "Highlights": {
        "MarketCapitalization": 3071033600,
        "MarketCapitalizationMln": 3071.0336,
        "EBITDA": -531758016,
        "PERatio": null,
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        "WallStreetTargetPrice": 33.9333,
        "BookValue": 5.837,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -2.88,
        "EPSEstimateCurrentYear": -2.3201,
        "EPSEstimateNextYear": -2.478,
        "EPSEstimateNextQuarter": -0.428,
        "EPSEstimateCurrentQuarter": -0.7053,
        "MostRecentQuarter": "2026-03-31",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.2695,
        "ReturnOnEquityTTM": -0.4959,
        "RevenueTTM": 0,
        "RevenuePerShareTTM": 0,
        "QuarterlyRevenueGrowthYOY": -1,
        "GrossProfitTTM": -406396992,
        "DilutedEpsTTM": -2.88,
        "QuarterlyEarningsGrowthYOY": 0
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    "Valuation": {
        "TrailingPE": 0,
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        "PriceSalesTTM": 3643.6484,
        "PriceBookMRQ": 3.4995,
        "EnterpriseValue": 2287707829,
        "EnterpriseValueRevenue": 2843.1605,
        "EnterpriseValueEbitda": 86.4829
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    "SharesStats": {
        "SharesOutstanding": 158709737,
        "SharesFloat": 144273499,
        "PercentInsiders": 9.131,
        "PercentInstitutions": 99.58200000000001,
        "SharesShort": null,
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        "ShortRatio": null,
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    "Technicals": {
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    "SplitsDividends": {
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        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
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    "AnalystRatings": {
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    "Holders": {
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                "name": "BlackRock Inc",
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                "totalAssets": 0.1126,
                "currentShares": 8519192,
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                "change_p": 0.2243
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                "name": "Temasek Holdings Ltd.",
                "date": "2026-03-31",
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                "change_p": 0
            },
            {
                "name": "State Street Corp",
                "date": "2026-03-31",
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                "change": 8630,
                "change_p": 0.1378
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            {
                "name": "NORGES BANK",
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                "change_p": 29.6965
            },
            {
                "name": "FMR Inc",
                "date": "2026-03-31",
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                "change_p": -24.9596
            },
            {
                "name": "UBS Asset Mgmt Americas Inc",
                "date": "2026-03-31",
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                "change_p": -11.0643
            },
            {
                "name": "The Goldman Sachs Group Inc",
                "date": "2026-03-31",
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            {
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                "date": "2026-03-31",
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            {
                "name": "Geode Capital Management, LLC",
                "date": "2026-03-31",
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            {
                "name": "Holocene Advisors, LP",
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            },
            {
                "name": "AllianceBernstein L.P.",
                "date": "2026-03-31",
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            {
                "name": "Dimensional Fund Advisors, Inc.",
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            {
                "name": "UBS Group AG",
                "date": "2026-03-31",
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            {
                "name": "Pictet Asset Manangement SA",
                "date": "2026-03-31",
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            },
            {
                "name": "Capital Research Global Investors",
                "date": "2026-03-31",
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                "change_p": -32.5711
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                "name": "Scottish Mortgage Ord",
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                "totalAssets": 0.6628,
                "currentShares": 7041270,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Vanguard Total Stock Mkt Idx Inv",
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            {
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                "change_p": 0.8498
            },
            {
                "name": "State Street\u00ae SPDR\u00ae S&P\u00ae Biotech ETF",
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            },
            {
                "name": "Vanguard Small Cap Index",
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                "change": -4200,
                "change_p": -0.135
            },
            {
                "name": "Vanguard US Growth Investor",
                "date": "2026-03-31",
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                "change": 0,
                "change_p": 0
            },
            {
                "name": "Baillie Gifford US Equity Growth",
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                "currentShares": 3037857,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "T. Rowe Price Small-Cap Stock",
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                "change": 154800,
                "change_p": 7.1146
            },
            {
                "name": "T. Rowe Price US Small-Cap Core Equity",
                "date": "2026-03-31",
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                "totalAssets": 0.5543,
                "currentShares": 2330622,
                "change": 151511,
                "change_p": 6.9529
            },
            {
                "name": "American Funds SMALLCAP World A",
                "date": "2026-03-31",
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                "totalAssets": 0.0524,
                "currentShares": 2208811,
                "change": -100198,
                "change_p": -4.3394
            },
            {
                "name": "Fidelity Growth Compy Commingled Pl S",
                "date": "2026-03-31",
                "totalShares": 1.2976,
                "totalAssets": 0.0381,
                "currentShares": 2059022,
                "change": 2711,
                "change_p": 0.1318
            },
            {
                "name": "Vanguard Small Cap Growth Index Inv",
                "date": "2026-04-30",
                "totalShares": 1.0949,
                "totalAssets": 0.0741,
                "currentShares": 1737304,
                "change": -1269,
                "change_p": -0.073
            },
            {
                "name": "Vanguard Institutional Extnd Mkt Idx Tr",
                "date": "2026-04-30",
                "totalShares": 1.054,
                "totalAssets": 0.0341,
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}
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