Stock Fundamentals

Company Information

Company Name
Castle Biosciences Inc
Sector
Healthcare
Industry
Diagnostics & Research
Exchange
NASDAQ
ISIN: US14843C1053
CIK: 0000908605
CUSIP: 14843C105
Currency: USD
Full Time Employees: 823
Phone: 866 788 9007
Fiscal Year End: December
IPO Date: Jul 25, 2019
Description:

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), uveal melanoma, and mental health conditions. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the risk of metastasis for patients with uveal melanoma; DecisionDx-SCC, a risk stratification test for cutaneous squamous cell carcinoma; MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a risk stratification spatial-omics test to predict future development of progression of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma; and IDgenetix, a pharmacogenomic test that helps guide optimal drug treatment for patients diagnosed with major depressive disorder, schizophrenia, bipolar disorder, anxiety disorders, social phobia, obsessive-compulsive personality disorder, post-traumatic stress disorder, and attention deficit hyperactivity disorder. The company offers its products to skin cancer and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

Address:

505 S. Friendswood Drive, Friendswood, TX, United States, 77546

Directors & Officers

Name Title Year Born
Mr. Derek J. Maetzold Founder, CEO, President & Director 1962
Mr. Frank Stokes CFO & Treasurer 1970
Ms. Kristen M. Oelschlager R.N. Chief Operating Officer 1968
Mr. Tobin W. Juvenal Chief Commercial Officer 1961
Ms. Camilla Zuckero Vice President of Investor Relations & Corporate Affairs NA
Mr. Kevin Doman Vice President of Sales NA
Dr. Jay Braxton Pharm.D. VP of Marketing & Brand Manager of Uveal Melanoma (UM) NA
Ms. Keli Greenberg Vice President of Human Resources NA
Dr. Matthew Goldberg M.D. Senior Vice President of Medical NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
BlackRock Inc 3.19M Sep 30, 2025 10.93% $0.00 1.12%
Vanguard Group Inc 2.20M Dec 31, 2025 7.54% $0.00 1.27%
RTW INVESTMENTS, LLC 2.12M Dec 31, 2025 7.25% $0.82 0.00%
Principal Financial Group Inc 1.79M Sep 30, 2025 6.15% $0.02 -0.26%
Portolan Capital Management, LLC 1.73M Dec 31, 2025 5.93% $3.60 14.15%
Dimensional Fund Advisors, Inc. 1.14M Dec 31, 2025 3.92% $0.01 -22.41%
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.06M Dec 31, 2025 3.63% $0.86 164.68%
Nuveen, LLC 957.08K Sep 30, 2025 3.28% $0.01 -10.81%
State Street Corp 724.08K Sep 30, 2025 2.48% $0.00 2.32%
Geode Capital Management, LLC 698.61K Sep 30, 2025 2.39% $0.00 1.26%
Allianz Asset Management AG 648.35K Sep 30, 2025 2.22% $0.02 -9.16%
AIGH Capital Management, LLC 624.72K Dec 31, 2025 2.14% $5.88 -11.67%
Millennium Management LLC 575.09K Sep 30, 2025 1.97% $0.01 34.24%
Palisade Capital Management LLc 567.78K Dec 31, 2025 1.95% $0.65 -11.10%
Wasatch Advisors LP 537.24K Dec 31, 2025 1.84% $0.12 -19.71%
Renaissance Technologies Corp 493.10K Dec 31, 2025 1.69% $0.03 -12.35%
Schroder Investment Management Group 492.16K Dec 31, 2025 1.69% $0.01 -0.56%
Acadian Asset Management LLC 451.65K Sep 30, 2025 1.55% $0.02 29,381.20%
Connor Clark & Lunn Inv Mgmt Ltd 388.49K Dec 31, 2025 1.33% $0.04 15.66%
The Goldman Sachs Group Inc 345.10K Sep 30, 2025 1.18% $0.00 26.21%

Shares Statistics

Shares Outstanding: 29.19M
Shares Float: 25.03M
% Insiders: 289.70%
% Institutions: 9,505.70%
Short % Float: 5.33%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 BlackRock Inc 3.19M 10.93% ▲ 1.12% Sep 30, 2025
2 Vanguard Group Inc 2.20M 7.54% ▲ 1.27% Dec 31, 2025
3 RTW INVESTMENTS, LLC 2.12M 7.25% ▲ 0.00% Dec 31, 2025
4 Principal Financial Group Inc 1.79M 6.15% ▼ 0.26% Sep 30, 2025
5 Portolan Capital Management, LLC 1.73M 5.93% ▲ 14.15% Dec 31, 2025
6 Dimensional Fund Advisors, Inc. 1.14M 3.92% ▼ 22.41% Dec 31, 2025
7 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 1.06M 3.63% ▲ 164.68% Dec 31, 2025
8 Nuveen, LLC 957.08K 3.28% ▼ 10.81% Sep 30, 2025
9 State Street Corp 724.08K 2.48% ▲ 2.32% Sep 30, 2025
10 Geode Capital Management, LLC 698.61K 2.39% ▲ 1.26% Sep 30, 2025

Valuation Metrics

Enterprise Value: $611.25M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $863.11M
EBITDA: $-2.04M
Book Value: $15.86
Earnings/Share: $-0.44
Profit Margin: -7.02%
Operating Margin: -27.50%
ROA (TTM): -4.82%
ROE (TTM): -5.21%
Revenue (TTM): $344.23M
Revenue/Share (TTM): $11.88
Earnings Growth (YOY): -51.60%
Revenue Growth (YOY): 0.80%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 5.26x 0.00x 0.19x -497.79x 0.15x
2024-12-31 7.29x 0.03x 0.14x 15.03x 0.31x
2023-12-31 6.20x 0.00x 0.14x -6,179.73x -0.03x
2022-12-31 8.09x 0.00x 0.11x -4,285.59x -0.03x
2021-12-31 14.21x 0.00x 0.11x -40,079.00x -0.03x
2020-12-31 20.58x 0.01x 0.05x -2.48x -0.82x
2019-12-31 7.63x 0.30x 0.29x 1.60x 2.44x
2018-12-31 2.69x -2.43x 1.45x -1.69x -6.51x
2017-12-31 1.28x -1.30x 2.45x -6.61x -1.79x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Feb 04, 2026 Derek J Maetzold N/A Sale 817.00 $37.99 $31.04K
Feb 03, 2026 Derek J Maetzold N/A Sale 3.20K $39.91 $127.71K
Jan 20, 2026 Derek J Maetzold N/A Sale 4.02K $40.01 $160.72K
Jan 06, 2026 Derek J Maetzold N/A Sale 1.34K $40.10 $53.69K
Jan 05, 2026 Derek J Maetzold N/A Sale 2.68K $38.09 $102.01K
Dec 22, 2025 Derek J Maetzold N/A Sale 830.00 $40.35 $33.49K
Dec 17, 2025 Derek J Maetzold N/A Sale 509.00 $40.04 $20.38K
Dec 17, 2025 Kristen M Oelschlager N/A Sale 14.89K $39.31 $585.25K
Dec 04, 2025 Derek J Maetzold N/A Sale 1.34K $40.03 $53.60K
Nov 25, 2025 Derek J Maetzold N/A Sale 5.12K $40.05 $204.86K
Nov 20, 2025 Tobin W Juvenal N/A Sale 4.69K $35.58 $166.98K
Nov 05, 2025 Derek J Maetzold N/A Sale 2.68K $31.85 $85.29K
Nov 04, 2025 Derek J Maetzold N/A Sale 6.70K $30.44 $203.80K
Oct 31, 2025 Kristen M Oelschlager N/A Sale 12.68K $25.04 $317.46K
Oct 20, 2025 Derek J Maetzold N/A Sale 1.34K $22.44 $30.05K
Sep 17, 2025 Derek J Maetzold N/A Sale 1.34K $21.97 $29.42K
Apr 21, 2025 Derek J Maetzold N/A Sale 1.24K $21.52 $26.60K
Apr 08, 2025 Derek J Maetzold N/A Sale 213.00 $20.03 $4.27K
Mar 26, 2025 Derek J Maetzold N/A Sale 1.24K $20.30 $25.09K
Mar 10, 2025 Derek J Maetzold N/A Sale 2.13K $19.52 $41.58K

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