AMLX.US Fundamentals - AlphaKey Financial

People

▼
Directors & Officers

Name	Title	Year Born
Mr. Joshua B. Cohen	Co-Founder, Co-CEO & Director	1992
Mr. Justin B. Klee	Co-CEO & Director	1991
Mr. James M. Frates M.B.A.	Chief Financial Officer	1967
Dr. Camille L. Bedrosian M.D.	Chief Medical Officer	1953
Mr. Tom Holmes	Chief Technical Operations Officer	NA
Ms. Lindsey Allen	Head of Investor Relations & Communications	NA
Ms. Gina M. Mazzariello J.D.	Chief Legal Officer & General Counsel	1972
Ms. Linda A. Arsenault	Chief Human Resources Officer	NA
Ms. Tammy Sarnelli	Global Head of Regulatory Affairs	NA
Dr. Machelle Manuel Ph.D.	VP & Head of Global Medical Affairs	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Jan 16, 2026	Joshua B Cohen	N/A	Sale	1.97K	$13.83	$27.30K	SEC
Jan 16, 2026	Justin B Klee	N/A	Sale	2.00K	$13.89	$27.71K	SEC
Jan 15, 2026	Joshua B Cohen	N/A	Sale	136.19K	$13.59	$1.85M	SEC
Jan 06, 2026	James M Frates	N/A	Sale	3.33K	$11.11	$36.95K	SEC
Jan 06, 2026	Joshua B Cohen	N/A	Sale	7.72K	$11.09	$85.56K	SEC
Dec 23, 2025	Karen Firestone	N/A	Purchase	8.10K	$12.45	$100.85K	SEC
Dec 01, 2025	Camille L Bedrosian	N/A	Sale	6.58K	$14.35	$94.42K	SEC
Sep 30, 2025	Camille L Bedrosian	N/A	Sale	12.04K	$14.58	$175.53K	SEC
Sep 30, 2025	Gina Mazzariello	N/A	Sale	8.83K	$14.58	$128.71K	SEC
Sep 30, 2025	James M Frates	N/A	Sale	10.56K	$14.65	$154.67K	SEC
Sep 30, 2025	Joshua B Cohen	N/A	Sale	29.93K	$14.35	$429.54K	SEC
Sep 30, 2025	Justin B Klee	N/A	Sale	29.98K	$14.38	$431.04K	SEC
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
FMR Inc	16.73M	Jun 30, 2026	13.33%	$0.01	0.59%
BlackRock Inc	8.83M	Jun 30, 2026	7.03%	$0.00	-0.02%
Perceptive Advisors LLC	8.33M	Jun 30, 2026	6.64%	$2.25	0.60%
TCG Crossover Management, LLC	6.24M	Jun 30, 2026	4.97%	$2.70	0.00%
COMMODORE CAPITAL LP	5.65M	Jun 30, 2026	4.50%	$6.04	0.00%
Jupiter Topco LLC	5.24M	Jun 30, 2026	4.17%	$0.04	0.00%
HHG PLC	4.99M	Mar 31, 2026	3.97%	$0.03	11.65%
Saturn V Capital Management LLC	4.62M	Jun 30, 2026	3.68%	$11.91	6.30%
Vanguard Capital Management, LLC	4.22M	Jun 30, 2026	3.37%	$0.00	2.00%
Morgan Stanley - Brokerage Accounts	3.13M	Jun 30, 2026	2.49%	$0.00	43.91%
Driehaus Capital Management LLC	3.04M	Jun 30, 2026	2.42%	$0.32	1.67%
First Light Asset Management, LLC	3.02M	Jun 30, 2026	2.41%	$3.30	-5.25%
Franklin Templeton Inc	2.95M	Jun 30, 2026	2.35%	$0.01	30.45%
The Goldman Sachs Group Inc	2.86M	Jun 30, 2026	2.28%	$0.00	8.84%
State Street Corp	2.60M	Jun 30, 2026	2.07%	$0.00	10.16%
Geode Capital Management, LLC	2.34M	Jun 30, 2026	1.86%	$0.00	5.63%
Adage Capital Partners Gp LLC	1.90M	Jun 30, 2026	1.51%	$0.05	-46.64%
JPMorgan Chase & Co	1.86M	Jun 30, 2026	1.48%	$0.00	1,067.24%
683 Capital Management LLC	1.53M	Mar 31, 2026	1.22%	$1.11	-7.27%
Siren, L.L.C.	1.48M	Jun 30, 2026	1.18%	$0.54	20.37%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard MStar Total Stk Mkt Idx Invest	3.80M	3.03%	▲ 0.32%	Sep 30, 2026
2	iShares Russell 2000 ETF	2.69M	2.15%	▼ 0.66%	Sep 30, 2026
3	Fidelity Advisor Biotechnology I	2.43M	1.94%	▲ 0.00%	Aug 31, 2026
4	Fidelity Small Cap Growth	2.12M	1.69%	▲ 0.00%	Jul 31, 2026
5	Franklin Biotechnology Discv A(acc)USD	1.72M	1.37%	▲ 0.00%	Sep 30, 2026
6	Fidelity Select Health Care	1.60M	1.27%	▲ 12.68%	Aug 31, 2026
7	Fidelity Select Biotechnology	1.47M	1.17%	▲ 33.99%	Aug 31, 2026
8	Eventide Healthcare & Life Sciences I	1.32M	1.06%	▼ 12.39%	Jun 30, 2026
9	Strategic Advisers Fidelity US TtlStk	1.31M	1.04%	▲ 15.22%	Aug 31, 2026
10	Fidelity Stock Selector Small Cap	1.26M	1.00%	▲ 0.01%	Jul 31, 2026
Financial Highlights

▼
Market Cap: $3.52B
EBITDA: $-161.73M
Book Value: $2.15
Earnings/Share: $-1.41
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -44.13%
ROE (TTM): -74.73%
Revenue (TTM): $-665.00K
Revenue/Share (TTM): $-0.01
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -99.60%
Valuation Metrics

Enterprise Value: $3.28B
Trailing P/E: 0.00
Forward P/E: 2.77
Shares Statistics

Shares Outstanding: 125.51M
Shares Float: 97.28M
% Insiders: 7.16%
% Institutions: 94.45%
Shares Short: 13.25M
Shares Short (Prior Month): 12.67M
Short Ratio: 9.49
Short % Float: 13.22%
Stock Price History

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Open price histogram
1 Year Price History

3 Years Price History

10 Years Price History

Max Price History

Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$0.00
Cost of Goods Sold
adjust
$-525.00K
Gross Profit
subtotal
$-525.00K
SG&A
adjust
$-62.89M
R&D
adjust
$-90.40M
Operating Income
subtotal
$-153.29M
Other / Non-Operating Items
adjust
$8.56M
Net Income
subtotal
$-144.74M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "AMLX",
        "Type": "Common Stock",
        "Name": "Amylyx Pharmaceuticals Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00DP10YT5",
        "ISIN": null,
        "LEI": null,
        "PrimaryTicker": "AMLX.US",
        "CUSIP": null,
        "CIK": "0001658551",
        "EmployerIdNumber": "",
        "FiscalYearEnd": "December",
        "IPODate": "2022-01-07",
        "InternationalDomestic": "Domestic",
        "Sector": "Healthcare",
        "Industry": "Drug Manufacturers - Specialty & Generic",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Pharmaceuticals",
        "GicSubIndustry": "Pharmaceuticals",
        "HomeCategory": "Domestic",
        "IsDelisted": false,
        "Description": "Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.",
        "Address": "55 Cambridge Parkway, Cambridge, MA, United States, 02142",
        "AddressData": {
            "Street": "55 Cambridge Parkway",
            "City": "Cambridge",
            "State": "MA",
            "Country": "United States",
            "ZIP": "02142"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Joshua B. Cohen",
                "Title": "Co-Founder, Co-CEO & Director",
                "YearBorn": "1992"
            },
            {
                "Name": "Mr. Justin B. Klee",
                "Title": "Co-CEO & Director",
                "YearBorn": "1991"
            },
            {
                "Name": "Mr. James M. Frates M.B.A.",
                "Title": "Chief Financial Officer",
                "YearBorn": "1967"
            },
            {
                "Name": "Dr. Camille L. Bedrosian M.D.",
                "Title": "Chief Medical Officer",
                "YearBorn": "1953"
            },
            {
                "Name": "Mr. Tom  Holmes",
                "Title": "Chief Technical Operations Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Lindsey  Allen",
                "Title": "Head of Investor Relations & Communications",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Gina M. Mazzariello J.D.",
                "Title": "Chief Legal Officer & General Counsel",
                "YearBorn": "1972"
            },
            {
                "Name": "Ms. Linda A. Arsenault",
                "Title": "Chief Human Resources Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Tammy  Sarnelli",
                "Title": "Global Head of Regulatory Affairs",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Machelle  Manuel Ph.D.",
                "Title": "VP & Head of Global Medical Affairs",
                "YearBorn": "NA"
            }
        ],
        "Phone": "617 682 0917",
        "WebURL": "https://amylyx.com",
        "LogoURL": "/img/logos/US/AMLX.png",
        "FullTimeEmployees": 136,
        "UpdatedAt": "2026-10-29"
    },
    "Highlights": {
        "MarketCapitalization": 3523151104,
        "MarketCapitalizationMln": 3523.1511,
        "EBITDA": -161734000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 43,
        "BookValue": 2.148,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -1.41,
        "EPSEstimateCurrentYear": -1.4841,
        "EPSEstimateNextYear": -1.0905,
        "EPSEstimateNextQuarter": -0.385,
        "EPSEstimateCurrentQuarter": -0.3577,
        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.4413,
        "ReturnOnEquityTTM": -0.7473,
        "RevenueTTM": -665000,
        "RevenuePerShareTTM": -0.008,
        "QuarterlyRevenueGrowthYOY": -0.996,
        "GrossProfitTTM": -92447000,
        "DilutedEpsTTM": -1.41,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 2.7739,
        "PriceSalesTTM": 0.6625,
        "PriceBookMRQ": 14.7257,
        "EnterpriseValue": 3276391126,
        "EnterpriseValueRevenue": 6446.6329,
        "EnterpriseValueEbitda": -11.707
    },
    "SharesStats": {
        "SharesOutstanding": 125513048,
        "SharesFloat": 97276778,
        "PercentInsiders": 7.156999999999999,
        "PercentInstitutions": 94.447,
        "SharesShort": 13249442,
        "SharesShortPriorMonth": 12666971,
        "ShortRatio": 9.49,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.1322
    },
    "Technicals": {
        "Beta": -0.092,
        "52WeekHigh": 41.14,
        "52WeekLow": 10.83,
        "50DayMA": 31.3085,
        "200DayMA": 19.9245,
        "SharesShort": 13249442,
        "SharesShortPriorMonth": 12666971,
        "ShortRatio": 9.49,
        "ShortPercent": 0.1322
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.8333,
        "TargetPrice": 43,
        "StrongBuy": 11,
        "Buy": 0,
        "Hold": 1,
        "Sell": 0,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
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                "name": "FMR Inc",
                "date": "2026-06-30",
                "totalShares": 13.3276,
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            {
                "name": "BlackRock Inc",
                "date": "2026-06-30",
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                "name": "Perceptive Advisors LLC",
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                "name": "COMMODORE CAPITAL LP",
                "date": "2026-06-30",
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                "change": 0,
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                "change_p": 0
            },
            {
                "name": "HHG PLC",
                "date": "2026-03-31",
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            {
                "name": "Saturn V Capital Management LLC",
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                "change_p": 6.304
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            {
                "name": "Vanguard Capital Management, LLC",
                "date": "2026-06-30",
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                "change_p": 1.9956
            },
            {
                "name": "Morgan Stanley - Brokerage Accounts",
                "date": "2026-06-30",
                "totalShares": 2.4944,
                "totalAssets": 0.003,
                "currentShares": 3130808,
                "change": 955261,
                "change_p": 43.909
            },
            {
                "name": "Driehaus Capital Management LLC",
                "date": "2026-06-30",
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                "change": 49823,
                "change_p": 1.6679
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            {
                "name": "First Light Asset Management, LLC",
                "date": "2026-06-30",
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                "currentShares": 3023256,
                "change": -167389,
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            {
                "name": "Franklin Templeton Inc",
                "date": "2026-06-30",
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                "currentShares": 2950225,
                "change": 688656,
                "change_p": 30.4504
            },
            {
                "name": "The Goldman Sachs Group Inc",
                "date": "2026-06-30",
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                "currentShares": 2858239,
                "change": 232248,
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            },
            {
                "name": "State Street Corp",
                "date": "2026-06-30",
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                "currentShares": 2603337,
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            },
            {
                "name": "Geode Capital Management, LLC",
                "date": "2026-06-30",
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                "currentShares": 2335315,
                "change": 124383,
                "change_p": 5.6258
            },
            {
                "name": "Adage Capital Partners Gp LLC",
                "date": "2026-06-30",
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                "change": -1660764,
                "change_p": -46.6407
            },
            {
                "name": "JPMorgan Chase & Co",
                "date": "2026-06-30",
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                "currentShares": 1863650,
                "change": 1703987,
                "change_p": 1067.2397
            },
            {
                "name": "683 Capital Management LLC",
                "date": "2026-03-31",
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                "change": -120000,
                "change_p": -7.2727
            },
            {
                "name": "Siren, L.L.C.",
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                "change": 250586,
                "change_p": 20.3728
            }
        ],
        "Funds": [
            {
                "name": "Vanguard MStar Total Stk Mkt Idx Invest",
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                "totalAssets": 0.0048,
                "currentShares": 3802035,
                "change": 12105,
                "change_p": 0.3194
            },
            {
                "name": "iShares Russell 2000 ETF",
                "date": "2026-09-30",
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                "totalAssets": 0.1016,
                "currentShares": 2694093,
                "change": -17953,
                "change_p": -0.662
            },
            {
                "name": "Fidelity Advisor Biotechnology I",
                "date": "2026-08-31",
                "totalShares": 1.9386,
                "totalAssets": 3.3831,
                "currentShares": 2433200,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Small Cap Growth",
                "date": "2026-07-31",
                "totalShares": 1.6858,
                "totalAssets": 0.4885,
                "currentShares": 2115961,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Franklin Biotechnology Discv A(acc)USD",
                "date": "2026-09-30",
                "totalShares": 1.3675,
                "totalAssets": 2.4005,
                "currentShares": 1716341,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Select Health Care",
                "date": "2026-08-31",
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                "totalAssets": 0.8,
                "currentShares": 1600000,
                "change": 180000,
                "change_p": 12.6761
            },
            {
                "name": "Fidelity Select Biotechnology",
                "date": "2026-08-31",
                "totalShares": 1.1713,
                "totalAssets": 0.7891,
                "currentShares": 1470117,
                "change": 372942,
                "change_p": 33.9911
            },
            {
                "name": "Eventide Healthcare & Life Sciences I",
                "date": "2026-06-30",
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                "totalAssets": 1.3208,
                "currentShares": 1324994,
                "change": -187450,
                "change_p": -12.3938
            },
            {
                "name": "Strategic Advisers Fidelity US TtlStk",
                "date": "2026-08-31",
                "totalShares": 1.0448,
                "totalAssets": 0.0167,
                "currentShares": 1311309,
                "change": 173200,
                "change_p": 15.2182
            },
            {
                "name": "Fidelity Stock Selector Small Cap",
                "date": "2026-07-31",
                "totalShares": 1.0021,
                "totalAssets": 0.3463,
                "currentShares": 1257800,
                "change": 118,
                "change_p": 0.0094
            },
            {
                "name": "Xtrackers S&P 500 Swap ETF 1C",
                "date": "2025-12-31",
                "totalShares": 0.988,
                "totalAssets": 0.1359,
                "currentShares": 1240007,
                "change": -9147,
                "change_p": -0.7323
            },
            {
                "name": "Janus Henderson Hrzn Biotec E2 USD",
                "date": "2026-06-30",
                "totalShares": 0.8589,
                "totalAssets": 0.9407,
                "currentShares": 1077974,
                "change": 43263,
                "change_p": 4.1812
            },
            {
                "name": "Fidelity Small Cap Growth K6",
                "date": "2026-07-31",
                "totalShares": 0.8393,
                "totalAssets": 0.4659,
                "currentShares": 1053389,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Small Cap Index",
                "date": "2026-07-31",
                "totalShares": 0.8023,
                "totalAssets": 0.06,
                "currentShares": 1007047,
                "change": 8692,
                "change_p": 0.8706
            },
            {
                "name": "Fidelity Series Small Cap Opps",
                "date": "2026-07-31",
                "totalShares": 0.8019,
                "totalAssets": 0.4318,
                "currentShares": 1006427,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "iShares Russell 2000 Growth ETF",
                "date": "2026-09-30",
                "totalShares": 0.7715,
                "totalAssets": 0.2,
                "currentShares": 968279,
                "change": -1226,
                "change_p": -0.1265
            },
            {
                "name": "JPMorgan Mid Cap Growth I",
                "date": "2026-08-31",
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                    "sellingAndMarketingExpenses": "200000.00",
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                    "ebit": "-39005000.00",
                    "ebitda": "-39004000.00",
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                    "otherOperatingExpenses": "39655000.00",
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                    "taxProvision": null,
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                    "netInterestIncome": "-2274000.00",
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                    "incomeTaxExpense": "2557000.00",
                    "totalRevenue": "650000.00",
                    "totalOperatingExpenses": "15061000.00",
                    "costOfRevenue": "24594000.00",
                    "totalOtherIncomeExpenseNet": "-3275000.00",
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                    "netInterestIncome": "-1100000.00",
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                    "totalRevenue": "1426000.00",
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        }
    }
}
Amylyx Pharmaceuticals Inc

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