Stock Fundamentals

Company Information

Company Name
Twist Bioscience Corp
Sector
Healthcare
Industry
Diagnostics & Research
Exchange
NASDAQ
ISIN: US90184D1000
CIK: 0001581280
CUSIP: 90184D100
Currency: USD
Full Time Employees: 979
Phone: 800 719 0671
Fiscal Year End: September
IPO Date: Oct 31, 2018
Description:

Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. The company offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mutagenesis experiments, DNA origami, DNA computing, data storage in DNA, and other applications; and immunoglobulin G proteins for customers focused on the pursuit of drug discovery and development. It also provides NGS tools comprising library preparation kits, human exome kits, and fixed and custom panels, as well as alliance panels used within diagnostic tests for various indications, population genetics research and biomarker discovery, translational research, microbiology, and applied markets research; and methylation detection kits for cancer, and rare and inherited disease study, as well as fast hybridization and full RNA sequencing workflow solution. In addition, it offers synthetic SARS-CoV-2 RNA reference sequences as positive controls to develop both NGS and reverse transcription-polymerase chain reaction assays; synthetic monkeypox controls; and various respiratory viral controls, including for influenzas, respiratory syncytial virus, rhinoviruses, SARS, MERS, and coronaviruses. Further, it offers SARS-CoV-2 Research Panels, such as the Twist Respiratory Virus Panel and the Pan-Viral Research Panel, for the detection of disease in a research setting; precision DNA libraries for antibody engineering, affinity maturation, and humanization; and antibody optimization solution to enable simultaneous optimization of multiple characteristics of a given antibody. The company has a strategic collaboration with bitBiome Inc. The company was incorporated in 2013 and is headquartered in South San Francisco, California.

Address:

681 Gateway Boulevard, South San Francisco, CA, United States, 94080

Directors & Officers

Name Title Year Born
Dr. Emily Marine Leproust Ph.D. Co-Founder, Board Chair & CEO 1974
Dr. Patrick John Finn Ph.D. President & COO 1972
Mr. Adam Laponis Chief Financial Officer 1977
Mr. Dennis Cho J.D. Chief Legal Officer & Corporate Secretary 1971
Ms. Paula Green Senior Vice President of Human Resources 1968
Mr. Robert F. Werner VP & Chief Accounting Officer 1973
Mr. Siyuan Chen Chief Technology Officer NA
Dr. Michael Fero Ph.D. Chief Information Officer NA
Dr. Colby Souders Ph.D. Chief Scientific Officer NA
Ms. Nicole Moreno Senior Vice President of Sales & Support NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
ARK Investment Management LLC 6.73M Sep 30, 2025 10.97% $1.13 5.10%
BlackRock Inc 6.18M Sep 30, 2025 10.08% $0.00 -1.56%
William Blair Investment Management, LLC 5.95M Dec 31, 2025 9.71% $0.53 43.75%
Artisan Partners Limited Partnership 5.83M Dec 31, 2025 9.51% $0.28 -9.06%
Vanguard Group Inc 5.78M Dec 31, 2025 9.42% $0.00 0.14%
EdgePoint Investment 5.38M Dec 31, 2025 8.77% $1.40 31.74%
State Street Corp 3.09M Sep 30, 2025 5.04% $0.00 23.51%
Amova Asset Management Americas, Inc 2.12M Sep 30, 2025 3.46% $0.58 -7.79%
Sumitomo Mitsui Trust Group Inc 2.12M Sep 30, 2025 3.46% $0.03 -7.79%
JPMorgan Chase & Co 2.04M Sep 30, 2025 3.32% $0.00 41.51%
Soleus Capital Management, L.P. 1.87M Sep 30, 2025 3.04% $2.64 426.59%
Amvescap Plc. 1.80M Sep 30, 2025 2.93% $0.01 -23.54%
Millennium Management LLC 1.79M Sep 30, 2025 2.93% $0.02 151.55%
The Goldman Sachs Group Inc 1.63M Sep 30, 2025 2.65% $0.01 6.69%
Morgan Stanley - Brokerage Accounts 1.49M Sep 30, 2025 2.43% $0.00 24.30%
Thrivent Financial For Lutherans 1.46M Sep 30, 2025 2.39% $0.08 14.45%
Geode Capital Management, LLC 1.45M Sep 30, 2025 2.36% $0.00 1.69%
Baillie Gifford & Co Limited. 1.28M Dec 31, 2025 2.08% $0.03 1.07%
First Light Asset Management, LLC 1.14M Dec 31, 2025 1.86% $2.77 -4.53%
UBS Asset Mgmt Americas Inc 1.12M Sep 30, 2025 1.83% $0.01 -7.85%

Shares Statistics

Shares Outstanding: 61.31M
Shares Float: 54.65M
% Insiders: 160.60%
% Institutions: 12,184.70%
Short % Float: 27.34%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 ARK Investment Management LLC 6.73M 10.97% ▲ 5.10% Sep 30, 2025
2 BlackRock Inc 6.18M 10.08% ▼ 1.56% Sep 30, 2025
3 William Blair Investment Management, LLC 5.95M 9.71% ▲ 43.75% Dec 31, 2025
4 Artisan Partners Limited Partnership 5.83M 9.51% ▼ 9.06% Dec 31, 2025
5 Vanguard Group Inc 5.78M 9.42% ▲ 0.14% Dec 31, 2025
6 EdgePoint Investment 5.38M 8.77% ▲ 31.74% Dec 31, 2025
7 State Street Corp 3.09M 5.04% ▲ 23.51% Sep 30, 2025
8 Amova Asset Management Americas, Inc 2.12M 3.46% ▼ 7.79% Sep 30, 2025
9 Sumitomo Mitsui Trust Group Inc 2.12M 3.46% ▼ 7.79% Sep 30, 2025
10 JPMorgan Chase & Co 2.04M 3.32% ▲ 41.51% Sep 30, 2025

Valuation Metrics

Enterprise Value: $2.78B
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $2.88B
EBITDA: $-112.75M
Book Value: $7.44
Earnings/Share: $-1.27
Profit Margin: -19.56%
Operating Margin: -31.73%
ROA (TTM): -13.49%
ROE (TTM): -16.79%
Revenue (TTM): $391.56M
Revenue/Share (TTM): $6.50
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 16.90%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-09-30 3.64x 0.03x 0.26x N/A -0.27x
2024-09-30 4.88x 0.03x 0.23x -7,614.86x -0.08x
2023-09-30 5.79x 0.02x 0.20x -43,431.80x -0.09x
2022-09-30 6.58x 0.02x 0.18x -3,112.76x -0.06x
2021-09-30 8.67x 0.02x 0.17x -416.15x -0.07x
2020-09-30 9.29x 0.03x 0.16x -177.99x -0.08x
2019-09-30 5.28x 0.05x 0.19x -84.12x -0.08x
2018-09-30 5.16x -0.05x 2.74x -53.74x -0.15x
2017-09-30 7.16x -0.14x 2.56x -64.62x -0.34x
2016-09-30 6.80x -0.15x 2.00x -58.52x -0.29x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Feb 12, 2026 Adam Laponis N/A Sale 7.00K $50.00 $350.00K
Feb 11, 2026 Dennis Cho N/A Sale 5.00K $49.93 $249.65K
Feb 06, 2026 Jan Johannessen N/A Sale 2.20K $47.91 $105.40K
Feb 04, 2026 Robert F Werner N/A Sale 7.00K $45.65 $319.55K
Feb 03, 2026 Dennis Cho N/A Sale 1.10K $46.58 $51.19K
Feb 03, 2026 Emily M Leproust N/A Sale 5.00K $46.58 $232.95K
Feb 03, 2026 Paula Green N/A Sale 1.19K $46.58 $55.62K
Feb 03, 2026 Robert F Werner N/A Sale 175.00 $46.58 $8.15K
Jan 13, 2026 Adam Laponis N/A Sale 3.00K $40.00 $120.00K
Jan 09, 2026 Adam Laponis N/A Sale 2.74K $35.26 $96.54K
Dec 22, 2025 Dennis Cho N/A Sale 324.00 $34.56 $11.20K
Dec 22, 2025 Paula Green N/A Sale 273.00 $34.56 $9.43K
Dec 22, 2025 Emily M Leproust N/A Sale 1.61K $34.56 $55.47K
Nov 03, 2025 Dennis Cho N/A Sale 1.02K $32.08 $32.69K
Nov 03, 2025 Emily M Leproust N/A Sale 4.89K $32.08 $156.77K
Nov 03, 2025 Paula Green N/A Sale 1.08K $32.08 $34.77K
Nov 03, 2025 Robert F Werner N/A Sale 160.00 $32.08 $5.13K
Oct 30, 2025 Adam Laponis N/A Sale 5.52K $31.44 $173.45K
Oct 30, 2025 Dennis Cho N/A Sale 6.52K $31.44 $204.83K
Oct 30, 2025 Emily M Leproust N/A Sale 31.38K $31.44 $986.56K

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