SLNO
Soleno Therapeutics Inc

SLNO.US soleno.life + Research + Basket
Healthcare · Biotechnology
CIK 0001484565
Employees 182
Phone 650 213 8444
Fiscal year end December
IPO Nov 13, 2014
Address 100 Marine Parkway, Redwood City, CA, United States, 94065
Price N/A
USD · NASDAQ
52-week range
29.43
69.99
Market Cap
2.76B
P/E Ratio
27.47
Forward P/E
13.12
Book Value
8.61
Div. Yield
N/A
% Institutions
111.53%
% Insiders
1.31%
1 Year

-29.9%
3 Year

+995.2%
10 Year

-44.8%
Description
Soleno Therapeutics, Inc., biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is VYKAT XR, an extended-release tablets for the treatment of Prader-Willi Syndrome. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is headquartered in Redwood City, California. As of May 18, 2026, Soleno Therapeutics, Inc. operates as a subsidiary of Neurocrine Biosciences, Inc.
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People

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Directors & Officers

Name	Title	Year Born
Dr. Anish Bhatnagar M.D.	Chairman, President & CEO	1970
Mr. James H. MacKaness	Executive Officer	1964
Ms. Meredith Manning M.B.A.	Chief Commercial Officer	1972
Mr. Kevin Norrett M.B.A., M.S.	Chief Business Officer	1973
Dr. Manher A. Joshi M.D.	Chief Development Officer	1968
Ms. Jennifer Fulk	Chief Financial Officer	1977
Mr. Jesse Schumaker	General Counsel	NA
Ms. Lauren Budesheim	Senior Vice President of People	NA
Ms. Kristen Yen M.S.	Senior Vice President of Global Clinical Operations and Patient Advocacy	1969
Dr. Neil M. Cowen M.B.A., Ph.D.	Senior Vice President of New Product Planning	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Jul 01, 2025	Patricia C Hirano	N/A	Sale	3.83K	$82.76	$316.97K	SEC
Jun 24, 2025	Patricia C Hirano	N/A	Sale	266.00	$84.25	$22.41K	SEC
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
HHG PLC	7.10M	Mar 31, 2026	13.62%	$0.11	-1.10%
FMR Inc	5.79M	Mar 31, 2026	11.11%	$0.01	-28.36%
Wellington Management Company LLP	4.43M	Mar 31, 2026	8.49%	$0.03	33.22%
BlackRock Inc	3.74M	Mar 31, 2026	7.18%	$0.00	-3.33%
Vanguard Group Inc	3.06M	Dec 31, 2025	5.87%	$0.00	9.02%
State Street Corp	2.68M	Mar 31, 2026	5.14%	$0.00	1.18%
venBio Select Advisor LLC	2.30M	Mar 31, 2026	4.41%	$0.76	-20.69%
Vanguard Capital Management, LLC	2.15M	Mar 31, 2026	4.13%	$0.00	0.00%
Nantahala Capital Management, LLC	1.74M	Mar 31, 2026	3.35%	$2.15	32.73%
Polar Capital Holdings PLC	1.70M	Mar 31, 2026	3.26%	$0.20	49.42%
Khrom Capital Management, LLC	1.51M	Mar 31, 2026	2.90%	$4.63	0.00%
Geode Capital Management, LLC	1.24M	Mar 31, 2026	2.37%	$0.00	6.38%
Woodline Partners LP	1.11M	Mar 31, 2026	2.13%	$0.14	0.03%
Deep Track Capital, LP	1.08M	Mar 31, 2026	2.07%	$0.59	7.87%
T. Rowe Price Associates, Inc.	1.03M	Mar 31, 2026	1.97%	$0.00	-69.09%
BRAIDWELL LP	959.26K	Mar 31, 2026	1.84%	$1.07	-19.24%
Readystate Asset Management LP	874.45K	Dec 31, 2025	1.68%	$1.64	324.89%
Franklin Resources Inc	835.18K	Mar 31, 2026	1.60%	$0.01	1.36%
Vestal Point Capital LP	730.00K	Mar 31, 2026	1.40%	$0.68	0.00%
COMMODORE CAPITAL LP	652.43K	Mar 31, 2026	1.25%	$1.26	-45.63%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Vanguard Health Care Inv	3.01M	5.78%	▲ 52.26%	Mar 31, 2026
2	Vanguard Total Stock Mkt Idx Inv	1.56M	3.00%	▲ 0.29%	Apr 30, 2026
3	Janus Henderson Global Life Sciences	987.38K	1.89%	▼ 1.46%	Mar 31, 2026
4	Janus Henderson Global Life Sciences D	987.38K	1.89%	▼ 0.24%	Mar 31, 2026
5	Janus Global Life Science AUSD	910.95K	1.75%	▲ 4.46%	Mar 31, 2026
6	International Biotechnology Ord	648.53K	1.24%	▲ 0.00%	Apr 30, 2026
7	Janus Henderson Triton D	614.56K	1.18%	▲ 0.00%	Mar 31, 2026
8	Janus Henderson US SMID Cap Growth	614.56K	1.18%	▼ 2.40%	Mar 31, 2026
9	Janus Henderson Hrzn Biotec E2 USD	614.07K	1.18%	▲ 0.00%	Mar 31, 2026
10	Vanguard Institutional Extnd Mkt Idx Tr	551.75K	1.06%	▲ 1.18%	Apr 30, 2026
Financial Highlights

▼
Market Cap: $2.76B
EBITDA: $91.52M
P/E Ratio: $27.47
PEG Ratio: $0.00
Book Value: $8.61
Earnings/Share: $1.93
Profit Margin: 33.70%
Operating Margin: 33.57%
ROA (TTM): 12.07%
ROE (TTM): 26.38%
Revenue (TTM): $285.01M
Revenue/Share (TTM): $5.45
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%
Valuation Metrics

Enterprise Value: $2.56B
Trailing P/E: 27.47
Forward P/E: 13.12
Shares Statistics

Shares Outstanding: 52.12M
Shares Float: 51.46M
% Insiders: 1.31%
% Institutions: 111.53%
Shares Short: 6.53M
Shares Short (Prior Month): 5.80M
Short Ratio: 1.01
Short % Float: 17.89%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$190.41M
Cost of Goods Sold
adjust
$-2.70M
Gross Profit
subtotal
$187.71M
SG&A
adjust
$-29.26M
R&D
adjust
$-40.63M
Other Operating Expense
adjust
$-102.87M
Operating Income
subtotal
$14.95M
Other / Non-Operating Items
adjust
$5.94M
Net Income
subtotal
$20.89M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
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        "Code": "SLNO",
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}
Soleno Therapeutics Inc

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