Fundamentals - AlphaKey Financial

Stock Fundamentals

Directors & Officers

▼
Name	Title	Year Born
Mr. Iain Gladstone Ross B.Sc., BSc (Hons), C.DIR, CH.D	Interim CEO & Chairman of the Board	1954
Ms. Rhonda L. Hellums	Executive VP, CFO, Secretary & Executive Director	1971
Dr. Steven J. Romano M.D.	Executive VP and Chief Research & Development Officer	1959
Dr. Marie Wikstrom Lindholm Ph.D.	Chief Scientific Officer	NA
Ms. Gem Gokmen Hopkins	Head of IR & Corporate Communications	NA
Mr. Jaimin B. Shah	SVP & General Counsel	NA
Mr. J.P. Gabriel	Chief Technical Operations Officer	NA
Mr. Curtis Rambaran M.D.	Chief Medical Officer	NA
Institutional Holders

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Holder Name	Shares	Date Reported	% Out	Value	% Change
TCG Crossover Management, LLC	3.03M	Mar 31, 2026	6.42%	$0.46	0.00%
Siren, L.L.C.	2.91M	Mar 31, 2026	6.16%	$0.43	0.00%
Redmile Group, LLC	2.16M	Mar 31, 2026	4.58%	$0.76	0.00%
Nantahala Capital Management, LLC	2.15M	Mar 31, 2026	4.54%	$0.42	39.18%
Citadel Advisors Llc	1.23M	Mar 31, 2026	2.61%	$0.00	405.94%
Millennium Management LLC	1.07M	Mar 31, 2026	2.27%	$0.00	62.86%
Great Point Partners LLC	1.02M	Mar 31, 2026	2.16%	$1.24	26.29%
Nextech Invest, Ltd.	952.40K	Dec 31, 2025	2.02%	$0.56	0.00%
Ikarian Capital, LLC	865.78K	Mar 31, 2026	1.83%	$0.14	0.00%
Polygon Management Ltd	630.16K	Mar 31, 2026	1.33%	$0.64	72.47%
5AM Venture Management, LLC	476.20K	Mar 31, 2026	1.01%	$0.70	0.00%
SG Americas Securities, LLC	286.70K	Mar 31, 2026	0.61%	$0.00	11.84%
UBS Group AG	246.94K	Mar 31, 2026	0.52%	$0.00	19.00%
BOOTHBAY FUND MANAGEMENT, LLC	209.09K	Mar 31, 2026	0.44%	$0.01	0.00%
BlackRock Inc	204.78K	Mar 31, 2026	0.43%	$0.00	179.93%
Bank of Montreal	202.90K	Mar 31, 2026	0.43%	$0.00	26.44%
BMO Capital Markets Corp.	202.90K	Mar 31, 2026	0.43%	$0.00	26.44%
ADAR1 Capital Management LLC	172.16K	Mar 31, 2026	0.36%	$0.05	628.15%
Marshall Wace Asset Management Ltd	169.62K	Mar 31, 2026	0.36%	$0.00	8.95%
Seven Fleet Capital Management LP	156.76K	Mar 31, 2026	0.33%	$0.26	6.21%
Shares Statistics

▼
Shares Outstanding: 47.23M
Shares Float: 74.75M
% Insiders: 2,437.70%
% Institutions: 4,441.30%
Short % Float: 5.56%
Fund Holdings

▼
Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	International Biotechnology Ord	729.62K	1.54%	▲ 0.00%	Feb 28, 2026
2	MEDICAL BioHealth EUR Acc	248.82K	0.53%	▼ 54.88%	Apr 30, 2026
3	apo Medical Opportunities R	231.19K	0.49%	▼ 25.97%	Mar 31, 2026
4	iShares Biotechnology ETF	170.79K	0.36%	▲ 0.64%	Apr 30, 2026
5	RIM Global Bioscience EUR	147.96K	0.31%	▲ 8.83%	Jan 31, 2026
6	Galileo - Biotech Innovation Fund S USD	58.65K	0.12%	▲ 0.00%	Oct 31, 2025
7	iShares Nasdaq US Biotech ETF USD Acc	37.49K	0.08%	▲ 0.00%	Apr 30, 2026
8	Vifag 2002 SICAV	30.00K	0.06%	▲ 0.00%	Feb 28, 2026
9	Fidelity Nasdaq Composite Index	29.54K	0.06%	▲ 0.00%	Mar 31, 2026
10	State Street® SPDR® S&P® Intl Sm Cp ETF	9.58K	0.02%	▲ 0.00%	Apr 30, 2026
Valuation Metrics

▼
Enterprise Value: $80.26M
Trailing P/E: 0.00
Forward P/E: 0.00
Financial Highlights

▼
Market Cap: $300.88M
EBITDA: $-71.08M
Book Value: $1.32
Earnings/Share: $-1.62
Profit Margin: 0.00%
Operating Margin: -3,565.40%
ROA (TTM): -29.79%
ROE (TTM): -92.56%
Revenue (TTM): $839.00K
Revenue/Share (TTM): $0.02
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 197.20%
Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

▼
Download Financials (Excel)
Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

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Financial Ratios

▼
Balance Sheet (Yearly)

▼
Date	Cash	Total Debt	Total Assets	Total Liabilities	Total Equity
2025-12-31	$11.28M	$N/A	$131.44M	$69.14M	$62.30M
2024-12-31	$96.95M	$N/A	$161.92M	$54.83M	$107.10M
2023-12-31	$68.79M	$N/A	$119.45M	$97.46M	$21.99M
2022-12-31	$54.82M	$N/A	$107.50M	$85.43M	$22.07M
2021-12-31	$73.54M	$N/A	$96.19M	$87.67M	$8.53M
2020-12-31	$27.45M	$N/A	$85.97M	$76.91M	$9.06M
2019-12-31	$13.52M	$N/A	$46.08M	$25.17M	$20.91M
2018-12-31	$21.49M	$N/A	$38.89M	$3.83M	$35.06M
2017-12-31	$42.75M	$N/A	$55.01M	$2.66M	$52.35M
2016-12-31	$39.01M	$N/A	$55.79M	$1.61M	$54.18M
2015-12-31	$51.91M	$N/A	$61.55M	$1.12M	$60.43M
2014-12-31	$16.86M	$N/A	$29.77M	$2.01M	$27.76M
2013-12-31	$15.89M	$N/A	$29.30M	$1.72M	$27.58M
2012-12-31	$8.91M	$N/A	$17.08M	$959.00K	$16.12M
2011-12-31	$3.69M	$N/A	$33.44M	$1.26M	$32.18M
2010-12-31	$3.57M	$N/A	$33.96M	$1.69M	$32.27M
2009-12-31	$1.13M	$N/A	$10.99M	$2.10M	$8.89M
2008-12-31	$3.35M	$N/A	$14.38M	$935.00K	$13.44M
2007-12-31	$10.17M	$N/A	$19.48M	$1.80M	$17.68M
2006-12-31	$8.82M	$N/A	$16.75M	$1.04M	$15.71M
2005-12-31	$9.09M	$N/A	$17.17M	$1.49M	$15.69M
2004-12-31	$2.63M	$N/A	$3.19M	$846.00K	$2.34M
2003-12-31	$5.09M	$N/A	$6.49M	$1.31M	$5.18M
2002-12-31	$7.16M	$N/A	$8.49M	$1.03M	$7.46M
2001-12-31	$9.08M	$N/A	$9.67M	$725.00K	$8.95M
2000-12-31	$11.43M	$N/A	$12.10M	$964.00K	$11.14M
1999-12-31	$10.53M	$N/A	$10.81M	$1.60M	$9.21M
1998-12-31	$3.66M	$N/A	$3.95M	$603.00K	$3.34M
1997-12-31	$5.18M	$N/A	$5.27M	$640.00K	$4.63M
1996-12-31	$6.70M	$N/A	$6.81M	$417.00K	$6.39M
1995-12-31	$1.25M	$N/A	$3.06M	$301.00K	$2.76M
Financial Ratios

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Date	Current Ratio	Debt/Equity	Debt/Assets	Interest Coverage	Debt/EBITDA
2025-12-31	8.72x	0.00x	0.53x	N/A	0.00x
2024-12-31	11.14x	0.00x	0.34x	N/A	0.00x
2023-12-31	4.62x	0.01x	0.82x	-1,458.94x	0.00x
2022-12-31	4.41x	0.02x	0.79x	-1,058.71x	-0.01x
2021-12-31	5.69x	0.02x	0.91x	-5,726.75x	0.00x
2020-12-31	2.99x	0.04x	0.89x	-2,240.44x	-0.01x
2019-12-31	3.88x	0.01x	0.55x	-688.91x	-0.01x
2018-12-31	7.70x	0.00x	0.10x	-457.13x	0.00x
2017-12-31	17.14x	0.00x	0.05x	-959.40x	0.00x
2016-12-31	26.09x	0.00x	0.03x	-7.71x	0.00x
2015-12-31	47.90x	0.00x	0.02x	-28.73x	0.00x
2014-12-31	11.05x	0.05x	0.07x	-82.50x	-0.12x
2013-12-31	12.34x	0.05x	0.06x	-129.60x	-0.14x
2012-12-31	9.45x	0.05x	0.06x	-877.13x	-0.16x
2011-12-31	3.10x	0.00x	0.04x	-445.08x	0.00x
2010-12-31	2.60x	0.00x	0.05x	-137.43x	0.00x
2009-12-31	0.83x	0.00x	0.19x	-164.22x	0.00x
2008-12-31	4.73x	0.00x	0.07x	-251.35x	0.00x
2007-12-31	6.46x	0.00x	0.09x	-10.64x	0.00x
2006-12-31	9.23x	0.00x	0.06x	-213.40x	0.00x
2005-12-31	7.20x	0.00x	0.09x	-3,898.00x	0.00x
2004-12-31	6.13x	0.00x	0.27x	-47.44x	0.00x
2003-12-31	4.92x	0.00x	0.20x	-12.38x	0.00x
2002-12-31	8.19x	0.00x	0.12x	-6.64x	0.00x
2001-12-31	13.24x	0.00x	0.07x	-6.32x	0.00x
2000-12-31	12.46x	0.00x	0.08x	-5.42x	0.00x
1999-12-31	6.74x	0.00x	0.15x	-13.37x	0.00x
1998-12-31	6.54x	0.00x	0.15x	-5.87x	0.00x
1997-12-31	8.18x	0.00x	0.12x	-5.42x	0.00x
1996-12-31	16.17x	0.00x	0.06x	-4.46x	0.00x
1995-12-31	10.17x	0.00x	0.10x	-15.81x	0.00x
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "SLN",
        "Type": "Common Stock",
        "Name": "Silence Therapeutics PLC",
        "Exchange": "NASDAQ",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG00WVTHPN2",
        "ISIN": "US82686Q1013",
        "LEI": null,
        "PrimaryTicker": "SLN.US",
        "CUSIP": "82686Q101",
        "CIK": "0001479615",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2020-09-08",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": "ADR",
        "IsDelisted": false,
        "Description": "Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.",
        "Address": "12 Hammersmith Grove, London, United Kingdom, W6 7AP",
        "AddressData": {
            "Street": "12 Hammersmith Grove",
            "City": "London",
            "Country": "United Kingdom",
            "ZIP": "W6 7AP"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Iain Gladstone Ross B.Sc., BSc (Hons), C.DIR, CH.D",
                "Title": "Interim CEO & Chairman of the Board",
                "YearBorn": "1954"
            },
            {
                "Name": "Ms. Rhonda L. Hellums",
                "Title": "Executive VP, CFO, Secretary & Executive Director",
                "YearBorn": "1971"
            },
            {
                "Name": "Dr. Steven J. Romano M.D.",
                "Title": "Executive VP and Chief Research & Development Officer",
                "YearBorn": "1959"
            },
            {
                "Name": "Dr. Marie Wikstrom Lindholm Ph.D.",
                "Title": "Chief Scientific Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Ms. Gem Gokmen Hopkins",
                "Title": "Head of IR & Corporate Communications",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Jaimin B. Shah",
                "Title": "SVP & General Counsel",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. J.P.  Gabriel",
                "Title": "Chief Technical Operations Officer",
                "YearBorn": "NA"
            },
            {
                "Name": "Mr. Curtis  Rambaran M.D.",
                "Title": "Chief Medical Officer",
                "YearBorn": "NA"
            }
        ],
        "Phone": "44 20 3457 6900",
        "WebURL": "https://www.silence-therapeutics.com",
        "LogoURL": "/img/logos/US/SLN.png",
        "FullTimeEmployees": 88,
        "UpdatedAt": "2026-06-03"
    },
    "Highlights": {
        "MarketCapitalization": 300884480,
        "MarketCapitalizationMln": 300.8845,
        "EBITDA": -71083000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 31.2,
        "BookValue": 1.319,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -1.62,
        "EPSEstimateCurrentYear": -0.4,
        "EPSEstimateNextYear": -0.39,
        "EPSEstimateNextQuarter": -0.11,
        "EPSEstimateCurrentQuarter": -0.11,
        "MostRecentQuarter": "2026-03-31",
        "ProfitMargin": 0,
        "OperatingMarginTTM": -35.654,
        "ReturnOnAssetsTTM": -0.2979,
        "ReturnOnEquityTTM": -0.9256,
        "RevenueTTM": 839000,
        "RevenuePerShareTTM": 0.018,
        "QuarterlyRevenueGrowthYOY": 1.972,
        "GrossProfitTTM": 667000,
        "DilutedEpsTTM": -1.62,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 358.6227,
        "PriceBookMRQ": 6.2435,
        "EnterpriseValue": 80264070,
        "EnterpriseValueRevenue": 95.6664,
        "EnterpriseValueEbitda": -5.7776
    },
    "SharesStats": {
        "SharesOutstanding": 47234613,
        "SharesFloat": 74748775,
        "PercentInsiders": 24.377,
        "PercentInstitutions": 44.413000000000004,
        "SharesShort": null,
        "SharesShortPriorMonth": null,
        "ShortRatio": null,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.0556
    },
    "Technicals": {
        "Beta": 1.515,
        "52WeekHigh": 8.4,
        "52WeekLow": 4.19,
        "50DayMA": 6.5762,
        "200DayMA": 6.0108,
        "SharesShort": 1985927,
        "SharesShortPriorMonth": 2156496,
        "ShortRatio": 6.42,
        "ShortPercent": 0.0556
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.1429,
        "TargetPrice": 31.2,
        "StrongBuy": 3,
        "Buy": 3,
        "Hold": 0,
        "Sell": 1,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
            {
                "name": "TCG Crossover Management, LLC",
                "date": "2026-03-31",
                "totalShares": 6.4223,
                "totalAssets": 0.4574,
                "currentShares": 3033560,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Siren, L.L.C.",
                "date": "2026-03-31",
                "totalShares": 6.1638,
                "totalAssets": 0.4253,
                "currentShares": 2911438,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Redmile Group, LLC",
                "date": "2026-03-31",
                "totalShares": 4.583,
                "totalAssets": 0.7555,
                "currentShares": 2164777,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Nantahala Capital Management, LLC",
                "date": "2026-03-31",
                "totalShares": 4.5448,
                "totalAssets": 0.4165,
                "currentShares": 2146731,
                "change": 604304,
                "change_p": 39.1788
            },
            {
                "name": "Citadel Advisors Llc",
                "date": "2026-03-31",
                "totalShares": 2.6142,
                "totalAssets": 0.0011,
                "currentShares": 1234807,
                "change": 990746,
                "change_p": 405.942
            },
            {
                "name": "Millennium Management LLC",
                "date": "2026-03-31",
                "totalShares": 2.2742,
                "totalAssets": 0.0024,
                "currentShares": 1074191,
                "change": 414599,
                "change_p": 62.8569
            },
            {
                "name": "Great Point Partners LLC",
                "date": "2026-03-31",
                "totalShares": 2.1605,
                "totalAssets": 1.236,
                "currentShares": 1020489,
                "change": 212457,
                "change_p": 26.2931
            },
            {
                "name": "Nextech Invest, Ltd.",
                "date": "2025-12-31",
                "totalShares": 2.0163,
                "totalAssets": 0.5598,
                "currentShares": 952400,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Ikarian Capital, LLC",
                "date": "2026-03-31",
                "totalShares": 1.8329,
                "totalAssets": 0.1406,
                "currentShares": 865784,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Polygon Management Ltd",
                "date": "2026-03-31",
                "totalShares": 1.3341,
                "totalAssets": 0.6447,
                "currentShares": 630161,
                "change": 264792,
                "change_p": 72.4725
            },
            {
                "name": "5AM Venture Management, LLC",
                "date": "2026-03-31",
                "totalShares": 1.0082,
                "totalAssets": 0.6967,
                "currentShares": 476200,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "SG Americas Securities, LLC",
                "date": "2026-03-31",
                "totalShares": 0.607,
                "totalAssets": 0.0016,
                "currentShares": 286698,
                "change": 30358,
                "change_p": 11.8429
            },
            {
                "name": "UBS Group AG",
                "date": "2026-03-31",
                "totalShares": 0.5228,
                "totalAssets": 0.0002,
                "currentShares": 246937,
                "change": 39424,
                "change_p": 18.9983
            },
            {
                "name": "BOOTHBAY FUND MANAGEMENT, LLC",
                "date": "2026-03-31",
                "totalShares": 0.4427,
                "totalAssets": 0.0143,
                "currentShares": 209088,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "BlackRock Inc",
                "date": "2026-03-31",
                "totalShares": 0.4335,
                "totalAssets": 0,
                "currentShares": 204777,
                "change": 131624,
                "change_p": 179.9297
            },
            {
                "name": "Bank of Montreal",
                "date": "2026-03-31",
                "totalShares": 0.4296,
                "totalAssets": 0.0004,
                "currentShares": 202901,
                "change": 42427,
                "change_p": 26.4386
            },
            {
                "name": "BMO Capital Markets Corp.",
                "date": "2026-03-31",
                "totalShares": 0.4296,
                "totalAssets": 0.0004,
                "currentShares": 202901,
                "change": 42427,
                "change_p": 26.4386
            },
            {
                "name": "ADAR1 Capital Management LLC",
                "date": "2026-03-31",
                "totalShares": 0.3645,
                "totalAssets": 0.0534,
                "currentShares": 172157,
                "change": 148514,
                "change_p": 628.1521
            },
            {
                "name": "Marshall Wace Asset Management Ltd",
                "date": "2026-03-31",
                "totalShares": 0.3591,
                "totalAssets": 0.0009,
                "currentShares": 169616,
                "change": 13936,
                "change_p": 8.9517
            },
            {
                "name": "Seven Fleet Capital Management LP",
                "date": "2026-03-31",
                "totalShares": 0.3319,
                "totalAssets": 0.2622,
                "currentShares": 156759,
                "change": 9159,
                "change_p": 6.2053
            }
        ],
        "Funds": [
            {
                "name": "International Biotechnology Ord",
                "date": "2026-02-28",
                "totalShares": 1.5447,
                "totalAssets": 0.9305,
                "currentShares": 729620,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "MEDICAL BioHealth EUR Acc",
                "date": "2026-04-30",
                "totalShares": 0.5268,
                "totalAssets": 0.1801,
                "currentShares": 248823,
                "change": -302618,
                "change_p": -54.8777
            },
            {
                "name": "apo Medical Opportunities R",
                "date": "2026-03-31",
                "totalShares": 0.4895,
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    }
}
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