Stock Fundamentals

Company Information

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Company Name
Lexicon Pharmaceuticals Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US5288723027
CIK: 0001062822
CUSIP: 528872104
Currency: USD
Full Time Employees: 103
Phone: 281 863 3000
Website: https://www.lexpharma.com
Fiscal Year End: December
IPO Date: Apr 07, 2000
Description:

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company offers Sotagliflozin, an orally-delivered small molecule drug to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease or CKD, and other cardiovascular risk factors. Its orally-delivered small molecule drug candidates under development include sotagliflozin for the treatment of hypertrophic cardiomyopathy or HCM and type 1 diabetes that is in Phase 3 clinical trial; LX9211, which has completed Phase II clinical trials for the treatment of neuropathic pain; and LX9851 for the treatment of obesity and associated cardiometabolic disorders, as well as for weight management. Lexicon Pharmaceuticals, Inc. has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

Address:

2445 Technology Forest Boulevard, The Woodlands, TX, United States, 77381

Directors & Officers

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Name Title Year Born
Dr. Michael S. Exton Ph.D. CEO & Director 1970
Ms. Kristen L. Alexander Vice President of Finance & Accounting 1968
Mr. Brian T. Crum Senior VP, General Counsel & Secretary 1973
Dr. Craig B. Granowitz M.D., Ph.D. Senior VP & Chief Medical Officer 1965
Mr. Scott M. Coiante Senior VP & CFO 1967
Ms. Lisa M. DeFrancesco Senior Vice President of Investor Relations & Corporate Communications 1980
Mr. Dixon Terry Vice President of Compliance NA
Ms. Carrie Siragusa Vice President of Marketing NA
Ms. Desiree Gendron Vice President of Sales & Training NA
Ms. Wendy E. McDermott Senior Vice President of Human Resources 1971

Institutional Holders

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Holder Name Shares Date Reported % Out Value % Change
Artal Group S A 136.18M Dec 31, 2025 32.59% $21.91 0.00%
Siren, L.L.C. 38.92M Dec 31, 2025 9.31% $1.34 0.00%
FMR Inc 37.83M Dec 31, 2025 9.05% $0.00 -2.19%
Vanguard Group Inc 9.61M Dec 31, 2025 2.30% $0.00 0.89%
Millennium Management LLC 3.83M Sep 30, 2025 0.92% $0.00 133.11%
BlackRock Inc 3.39M Sep 30, 2025 0.81% $0.00 1.20%
Sessa Capital, L.P 3.00M Dec 31, 2025 0.72% $0.06 0.00%
Citadel Advisors Llc 2.63M Sep 30, 2025 0.63% $0.00 0.00%
Geode Capital Management, LLC 2.40M Sep 30, 2025 0.57% $0.00 0.85%
Atlantic Trust Group, LLC 1.95M Dec 31, 2025 0.47% $0.00 -18.76%
Charles Schwab Investment Management Inc 1.06M Dec 31, 2025 0.25% $0.00 -7.82%
GSA Capital Partners LLP 996.24K Dec 31, 2025 0.24% $0.10 -17.18%
Susquehanna International Group, LLP 962.06K Sep 30, 2025 0.23% $0.00 27.32%
State Street Corp 880.12K Sep 30, 2025 0.21% $0.00 7.51%
Hennion & Walsh Asset Management Inc 779.21K Sep 30, 2025 0.19% $0.04 -1.79%
Royal Bank of Canada 722.44K Sep 30, 2025 0.17% $0.00 -53.36%
Two Sigma Investments LLC 637.31K Dec 31, 2025 0.15% $0.00 14.01%
Amvescap Plc. 521.40K Sep 30, 2025 0.12% $0.00 23.94%
Jane Street Group LLC 456.53K Sep 30, 2025 0.11% $0.00 -43.26%
Compagnie Lombard, Odier SCA 410.00K Dec 31, 2025 0.10% $0.01 0.00%

Shares Statistics

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Shares Outstanding: 417.87M
Shares Float: 359.56M
% Insiders: 103.40%
% Institutions: 6,645.90%
Short % Float: 13.28%

🏆 Top 10 Institutional Holders

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Rank Holder Name Shares Held % of Shares Change Date Reported
1 Artal Group S A 136.18M 32.59% ▲ 0.00% Dec 31, 2025
2 Siren, L.L.C. 38.92M 9.31% ▲ 0.00% Dec 31, 2025
3 FMR Inc 37.83M 9.05% ▼ 2.19% Dec 31, 2025
4 Vanguard Group Inc 9.61M 2.30% ▲ 0.89% Dec 31, 2025
5 Millennium Management LLC 3.83M 0.92% ▲ 133.11% Sep 30, 2025
6 BlackRock Inc 3.39M 0.81% ▲ 1.20% Sep 30, 2025
7 Sessa Capital, L.P 3.00M 0.72% ▲ 0.00% Dec 31, 2025
8 Citadel Advisors Llc 2.63M 0.63% ▲ 0.00% Sep 30, 2025
9 Geode Capital Management, LLC 2.40M 0.57% ▲ 0.85% Sep 30, 2025
10 Atlantic Trust Group, LLC 1.95M 0.47% ▼ 18.76% Dec 31, 2025

Valuation Metrics

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Enterprise Value: $554.37M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

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Market Cap: $614.26M
EBITDA: $-53.94M
PEG Ratio: $-0.14
Book Value: $0.33
Earnings/Share: $-0.19
Profit Margin: -96.77%
Operating Margin: -85.93%
ROA (TTM): -12.94%
ROE (TTM): -45.92%
Revenue (TTM): $70.86M
Revenue/Share (TTM): $0.20
Earnings Growth (YOY): -63.40%
Revenue Growth (YOY): 710.40%

Stock Price History

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1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

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Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

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Financial Ratios (Yearly)

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Financial Ratios (Quarterly)

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Earnings History

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Balance Sheet (Yearly)

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Financial Ratios

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Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2024-12-31 5.44x 0.70x 0.51x -12.65x -0.55x
2023-12-31 5.60x 1.08x 0.59x -13.11x -0.59x
2022-12-31 6.08x 0.43x 0.40x -36.24x -0.50x
2021-12-31 4.02x 0.01x 0.17x -108.59x -0.01x
2020-12-31 3.37x 0.08x 0.23x -3.29x -0.30x
2019-12-31 5.17x 2.10x 0.72x 6.84x 1.66x
2018-12-31 4.72x -0.16x 1.09x -4.97x -2.39x
2017-12-31 2.59x 4.48x 0.88x -19.57x -1.87x
2016-12-31 2.17x 0.44x 0.67x -20.89x -0.55x
2015-12-31 4.33x 0.28x 0.56x 0.22x 6.91x
2014-12-31 8.21x 0.34x 0.40x -44.55x -1.01x
2013-12-31 6.97x -0.01x 0.38x -51.94x -0.14x
2012-12-31 12.63x 0.05x 0.28x -51.28x -0.14x
2011-12-31 11.32x 0.16x 0.31x -45.13x -0.44x
2010-12-31 19.93x 0.12x 0.33x -35.20x -0.30x
2009-12-31 3.33x 0.41x 0.37x -30.33x -0.79x
2008-12-31 5.16x 0.16x 0.25x -35.87x -0.35x
2007-12-31 7.49x 0.12x 0.22x -27.05x -0.49x
2006-12-31 1.86x 0.38x 0.55x -16.98x -0.81x
2005-12-31 1.85x 0.43x 0.61x -11.01x -1.51x
2004-12-31 2.55x 0.31x 0.43x -17.84x -1.09x
2003-12-31 5.40x 0.34x 0.42x -192.59x -1.37x
2002-12-31 6.25x 0.02x 0.16x -8,984.71x -0.09x
2001-12-31 8.86x 0.00x 0.09x -138.98x 0.00x
2000-12-31 18.35x 0.01x 0.06x -84.06x -0.09x
1999-12-31 1.19x 1.15x 0.63x N/A -0.87x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Feb 23, 2026 Raymond Debbane N/A Purchase 100.00K $1.47 $147.00K
Feb 20, 2026 Raymond Debbane N/A Purchase 100.00K $1.48 $148.00K
Feb 19, 2026 Raymond Debbane N/A Purchase 50.00K $1.44 $72.00K
Feb 02, 2026 Invus Global Management, Llc N/A Purchase 1.54M $1.30 $2.00M

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