Stock Fundamentals

Company Information

Company Name
Kymera Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US5015751044
CIK: 0001815442
CUSIP: 501575104
Currency: USD
Full Time Employees: 225
Phone: 857 285 5300
Fiscal Year End: December
IPO Date: Aug 21, 2020
Description:

Kymera Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing KT-621, an oral STAT6 degrader in Phase 2b clinical trials for moderate to severe atopic dermatitis, asthma, COPD, EoE, CRSwNP, CSU, PN, BP, and others; KT-579, an oral IRF5 degrader in Phase 1 trials for autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, SSc, DM, and others; KT-485/SAR447971, IRAK4 program, which is in Phase II clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa and atopic dermatitis; and cyclin-dependent kinase 2 (CDK2) with broad oncology treatment potential, including in breast cancer and other solid tumors. The company has a strategic alliance with Sanofi S.A. for the development of drug candidates targeting IRAK4 outside the oncology and immuno-oncology fields. Kymera Therapeutics, Inc. was incorporated in 2015 and is headquartered in Watertown, Massachusetts.

Address:

500 North Beacon Street, Watertown, MA, United States, 02472

Directors & Officers

Name Title Year Born
Dr. Bruce L. Booth DPHIL, Ph.D. Co-Founder & Independent Chairman 1974
Dr. Nello Mainolfi M.D., Ph.D. Co-Founder, President, CEO & Director 1979
Mr. Bruce N. Jacobs CFA Chief Financial Officer NA
Dr. Jeremy G. Chadwick Ph.D. Chief Operating Officer 1963
Dr. Jared A. Gollob M.D. Chief Medical Officer 1965
Ms. Justine E. Koenigsberg Vice President of Investor Relations NA
Mr. Brian R. Adams J.D. Chief Legal Officer & Corporate Secretary 1974
Dr. Neil Graham M.D., M.P.H., MBBS Chief Development Officer 1959
Ms. Karen Weisbach Head of People & Culture NA
Dr. Juliet Williams B.A Ph.D. Head of Research NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
FMR Inc 8.93M Dec 31, 2025 10.94% $0.04 51.86%
Baker Bros Advisors LP 8.66M Dec 31, 2025 10.60% $3.94 30.16%
venBio Select Advisor LLC 6.35M Sep 30, 2025 7.78% $4.65 -3.14%
Vanguard Group Inc 6.27M Dec 31, 2025 7.68% $0.01 15.60%
Bvf Inc 5.50M Dec 31, 2025 6.74% $14.41 0.00%
T. Rowe Price Associates, Inc. 5.10M Sep 30, 2025 6.24% $0.03 -25.69%
Atlas Venture Life Science Advisors, LLC 4.66M Dec 31, 2025 5.71% $41.91 -4.83%
Wellington Management Company LLP 4.41M Dec 31, 2025 5.41% $0.06 -15.07%
BlackRock Inc 4.37M Sep 30, 2025 5.35% $0.00 5.24%
Siren, L.L.C. 3.29M Dec 31, 2025 4.03% $7.63 -4.12%
State Street Corp 2.02M Sep 30, 2025 2.47% $0.00 29.92%
Geode Capital Management, LLC 1.28M Sep 30, 2025 1.56% $0.00 7.01%
Capital Research Global Investors 1.26M Sep 30, 2025 1.55% $0.01 0.00%
Driehaus Capital Management LLC 1.07M Dec 31, 2025 1.31% $0.57 13.86%
UBS Asset Mgmt Americas Inc 863.76K Sep 30, 2025 1.06% $0.01 5.47%
Merck & Co Inc 772.17K Sep 30, 2025 0.95% $19.17 0.00%
Holocene Advisors, LP 761.21K Dec 31, 2025 0.93% $0.12 -9.42%
COMMODORE CAPITAL LP 750.00K Sep 30, 2025 0.92% $2.07 0.00%
The Goldman Sachs Group Inc 711.44K Sep 30, 2025 0.87% $0.00 155.24%
UBS Group AG 648.72K Sep 30, 2025 0.79% $0.01 16.31%

Shares Statistics

Shares Outstanding: 80.00M
Shares Float: 53.86M
% Insiders: 225.70%
% Institutions: 11,308.10%
Short % Float: 14.76%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 FMR Inc 8.93M 10.94% ▲ 51.86% Dec 31, 2025
2 Baker Bros Advisors LP 8.66M 10.60% ▲ 30.16% Dec 31, 2025
3 venBio Select Advisor LLC 6.35M 7.78% ▼ 3.14% Sep 30, 2025
4 Vanguard Group Inc 6.27M 7.68% ▲ 15.60% Dec 31, 2025
5 Bvf Inc 5.50M 6.74% ▲ 0.00% Dec 31, 2025
6 T. Rowe Price Associates, Inc. 5.10M 6.24% ▼ 25.69% Sep 30, 2025
7 Atlas Venture Life Science Advisors, LLC 4.66M 5.71% ▼ 4.83% Dec 31, 2025
8 Wellington Management Company LLP 4.41M 5.41% ▼ 15.07% Dec 31, 2025
9 BlackRock Inc 4.37M 5.35% ▲ 5.24% Sep 30, 2025
10 Siren, L.L.C. 3.29M 4.03% ▼ 4.12% Dec 31, 2025

Valuation Metrics

Enterprise Value: $6.89B
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $7.31B
EBITDA: $-337.23M
Book Value: $19.42
Earnings/Share: $-3.60
Profit Margin: 0.00%
Operating Margin: -3,411.01%
ROA (TTM): -15.88%
ROE (TTM): -25.78%
Revenue (TTM): $39.21M
Revenue/Share (TTM): $0.46
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -61.20%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

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Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 10.47x 0.01x 0.09x -1,403.21x -0.05x
2024-12-31 7.53x 0.02x 0.15x -1,050.74x -0.06x
2023-12-31 4.73x 0.02x 0.31x -844.54x -0.04x
2022-12-31 5.88x 0.01x 0.19x -916.23x -0.03x
2021-12-31 4.88x 0.01x 0.24x -574.46x -0.04x
2020-12-31 2.73x 0.01x 0.42x -402.64x -0.07x
2019-12-31 2.69x -0.05x 1.64x -917.50x -0.08x
2018-12-31 8.92x -0.01x 1.78x -1,340.69x -0.01x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Feb 25, 2026 Nello Mainolfi N/A Sale 30.00K $90.26 $2.71M
Dec 31, 2025 Nello Mainolfi N/A Sale 30.00K $78.06 $2.34M
Dec 12, 2025 Bruce Booth N/A Sale 678.00 $91.04 $61.73K
Dec 11, 2025 Bros. Advisors Lp Baker N/A Purchase 2.01M $86.00 $172.50M
Dec 11, 2025 Bruce Booth N/A Sale 6.10K $91.23 $556.59K
Dec 10, 2025 Bruce Booth N/A Sale 229.81K $91.73 $21.08M
Dec 08, 2025 Jared Gollob N/A Sale 49.31K $88.67 $4.37M
Dec 08, 2025 Jeffrey W Albers N/A Sale 5.00K $89.76 $448.80K
Dec 08, 2025 Nello Mainolfi N/A Sale 100.00K $89.17 $8.92M
Oct 29, 2025 Nello Mainolfi N/A Sale 30.00K $60.99 $1.83M
Oct 15, 2025 Jared Gollob N/A Sale 59.58K $61.42 $3.66M
Oct 13, 2025 Jared Gollob N/A Sale 3.11K $60.00 $186.84K
Oct 13, 2025 Jeffrey W Albers N/A Sale 5.00K $59.19 $295.95K
Sep 17, 2025 Bruce N Jacobs N/A Sale 79.22K $50.00 $3.96M
Sep 16, 2025 Nello Mainolfi N/A Sale 30.00K $49.00 $1.47M
Jun 30, 2025 Bros. Advisors Lp Baker N/A Purchase 655.50K $44.00 $28.84M
Jun 30, 2025 Bvf Partners L P/Il N/A Purchase 317.17K $44.00 $13.96M
Jun 03, 2025 Elena Ridloff N/A Sale 12.00K $46.10 $553.20K
Jun 03, 2025 Jeffrey W. Albers N/A Sale 6.35K $49.00 $311.10K
Jun 03, 2025 Nello Mainolfi N/A Sale 30.00K $49.00 $1.47M

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