Stock Fundamentals

Company Information

Company Name
Iteos Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US46565G1040
CIK: 0001808865
CUSIP: 46565G104
Currency: USD
Full Time Employees: 173
Phone: 339 217 0161
Fiscal Year End: December
IPO Date: Jul 24, 2020
Description:

iTeos Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of immuno-oncology therapeutics for patients with cancer. The company's lead antibody product candidate, belrestotug, an antagonist of T-cell immunoreceptor with Ig and ITIM domains (TIGIT), as well as engages the Fc gamma receptor to activate dendritic cells, natural killer cells, T lymphocytes, and macrophages and to promote the release of cytotoxic granules and antibody-dependent cellular cytotoxicity activity. Its product pipeline also includes inupadenant, a next-generation A2AR antagonist program; EOS-984, a small molecule targeting equilibrative nucleoside transporter 1 (ENT1) to reverse immunosuppression and restore T cell proliferation in the tumor microenvironment; and EOS-215, a monoclonal antibody which antagonizes triggering receptor expressed on triggering receptor expressed on myeloid cells 2. Iteos Therapeutics, Inc. was founded in 2011 and is headquartered in Watertown, Massachusetts. As of August 28, 2025, iTeos Therapeutics, Inc. operates as a subsidiary of Concentra Biosciences, LLC.

Address:

321 Arsenal Street, Watertown, MA, United States, 02472

Directors & Officers

Name Title Year Born
Dr. Michel Detheux Ph.D. President, CEO & Director 1966
Mr. Matthew A. Call M.B.A. Chief Operating Officer 1973
Dr. David Feltquate M.D., Ph.D. Chief Medical Officer NA
Mr. Matthew Gall Chief Financial Officer 1977
Dr. Yvonne McGrath Ph.D. Chief Scientific Officer 1974
Ms. Adi Osovsky Executive Vice President of Legal NA
Mr. Philippe Brantegem Chief People Officer NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
EcoR1 Capital, LLC 10.69M Jun 30, 2025 24.18% $6.31 0.00%
BlackRock Inc 4.57M Jun 30, 2025 10.35% $0.00 1.45%
TANG CAPITAL MANAGEMENT LLC 3.83M Jun 30, 2025 8.66% $1.93 42.30%
Vanguard Group Inc 1.66M Jun 30, 2025 3.76% $0.00 -3.61%
Dimensional Fund Advisors, Inc. 832.76K Jun 30, 2025 1.88% $0.00 -29.50%
Boxer Capital Management, LLC 825.00K Jun 30, 2025 1.87% $4.14 0.00%
Geode Capital Management, LLC 703.47K Jun 30, 2025 1.59% $0.00 8.22%
Orbimed Advisors, LLC 700.00K Jun 30, 2025 1.58% $0.17 0.00%
Marshall Wace Asset Management Ltd 611.65K Jun 30, 2025 1.38% $0.01 411.59%
Renaissance Technologies Corp 602.10K Jun 30, 2025 1.36% $0.01 -6.74%
JPMorgan Chase & Co 601.36K Jun 30, 2025 1.36% $0.00 -69.67%
Nantahala Capital Management, LLC 596.67K Jun 30, 2025 1.35% $0.23 0.00%
State Street Corp 594.56K Jun 30, 2025 1.35% $0.00 2.16%
DLD Asset Management, LP 576.66K Jun 30, 2025 1.30% $0.48 0.00%
Newtyn Management LLC 567.42K Jun 30, 2025 1.28% $0.86 0.00%
LMR Partners LLP 550.00K Jun 30, 2025 1.24% $0.04 0.00%
Alyeska Investment Group, L.P. 500.00K Jun 30, 2025 1.13% $0.02 0.00%
Almitas Capital LLC 487.20K Jun 30, 2025 1.10% $1.23 77.09%
Millennium Management LLC 477.19K Jun 30, 2025 1.08% $0.00 36.98%
Morgan Stanley - Brokerage Accounts 429.34K Jun 30, 2025 0.97% $0.00 70.96%

Shares Statistics

Shares Outstanding: 44.21M
Shares Float: 33.49M
% Insiders: 34.90%
% Institutions: 9,028.30%
Short % Float: 5.78%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 EcoR1 Capital, LLC 10.69M 24.18% ▲ 0.00% Jun 30, 2025
2 BlackRock Inc 4.57M 10.35% ▲ 1.45% Jun 30, 2025
3 TANG CAPITAL MANAGEMENT LLC 3.83M 8.66% ▲ 42.30% Jun 30, 2025
4 Vanguard Group Inc 1.66M 3.76% ▼ 3.61% Jun 30, 2025
5 Dimensional Fund Advisors, Inc. 832.76K 1.88% ▼ 29.50% Jun 30, 2025
6 Boxer Capital Management, LLC 825.00K 1.87% ▲ 0.00% Jun 30, 2025
7 Geode Capital Management, LLC 703.47K 1.59% ▲ 8.22% Jun 30, 2025
8 Orbimed Advisors, LLC 700.00K 1.58% ▲ 0.00% Jun 30, 2025
9 Marshall Wace Asset Management Ltd 611.65K 1.38% ▲ 411.59% Jun 30, 2025
10 Renaissance Technologies Corp 602.10K 1.36% ▼ 6.74% Jun 30, 2025

Valuation Metrics

Enterprise Value: $-61.62M
Trailing P/E: 0.00
Forward P/E: 12.56

Financial Highlights

Market Cap: $448.68M
EBITDA: $-202.05M
Book Value: $12.90
Earnings/Share: $-4.73
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -18.49%
ROE (TTM): -34.97%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): -88.60%
Revenue Growth (YOY): -100.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2024-12-31 12.62x 0.00x 0.14x N/A -0.01x
2023-12-31 13.76x 0.00x 0.14x N/A -0.01x
2022-12-31 14.96x 0.00x 0.12x 6.60x 0.01x
2021-12-31 2.88x 0.00x 0.38x 177.21x 0.01x
2020-12-31 22.64x 0.00x 0.06x -37.17x 0.00x
2019-12-31 1.98x 0.27x 0.49x N/A -0.20x
2018-12-31 4.72x 0.13x 0.45x -325.77x -0.11x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Jun 10, 2025 Michel Detheux N/A Sale 43.88K $10.02 $439.71K
Jun 09, 2025 Michel Detheux N/A Sale 8.40K $10.03 $84.25K
Jun 09, 2025 Michel Detheux N/A Sale 43.88K $10.03 $440.14K
Jun 06, 2025 David Hallal N/A Sale 38.23K $10.24 $391.45K
Jun 06, 2025 Michel Detheux N/A Sale 8.40K $10.21 $85.76K
Jun 06, 2025 Michel Detheux N/A Sale 43.88K $10.21 $448.04K
Jun 05, 2025 David Hallal N/A Sale 38.23K $10.15 $388.00K
Jun 04, 2025 Michel Detheux N/A Sale 8.40K $10.10 $84.84K
Jun 04, 2025 Michel Detheux N/A Sale 43.88K $10.10 $443.22K
May 13, 2025 Ansbert Gadicke N/A Sale 1.03M $8.06 $8.32M
May 13, 2025 Bioventures 2018 L.P. Mpm N/A Sale 630.19K $8.06 $5.08M
Nov 19, 2024 Matthew Gall N/A Purchase 5.00K $7.73 $38.65K

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