Stock Fundamentals

Company Information

Company Name
Fulcrum Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US3596161097
CIK: 0001680581
CUSIP: 359616109
Currency: USD
Full Time Employees: 55
Phone: 617 651 8851
Fiscal Year End: December
IPO Date: Jul 18, 2019
Description:

Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage product candidate is pociredir, a fetal hemoglobin inducer, which is in phase 1b clinical trial for the treatment of sickle cell disease and beta-thalassemia. The company also discovers programs for the treatment of diamond-blackfan anemia, Bone Marrow Failure Syndromes, novel fetal hemoglobin inducers, fibrotic disorders. It has licensce agreement with CAMP4 which includes certain small molecule compounds, composition of matter and method of use patent rights, and know-how to research, develop, manufacture, use, and commercialize. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Address:

26 Landsdowne Street, Cambridge, MA, United States, 02139

Directors & Officers

Name Title Year Born
Mr. Alexander C. Sapir CEO, President & Director 1967
Mr. Alan A. Musso C.M.A., CPA Chief Financial Officer 1962
Mr. Curtis G. Oltmans J.D. Chief Legal Officer, Head of External Affairs & Corporate Secretary 1963
Dr. Bradley E. Bernstein M.D., Ph.D. Founder NA
Dr. Michael R. Green Founder NA
Dr. Rudolf Jaenisch M.D., Ph.D. Founder NA
Dr. Tsun-Huei Lee M.D., Ph.D. Founder 1964
Dr. Danny Reinberg Founder NA
Mr. Gregory Tourangeau Controller & Principal Accounting Officer NA
Dr. Jeffrey W. Jacobs Ph.D. Chief Scientific Officer 1963

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Jan 02, 2026 Robert J Gould N/A Sale 15.00K $11.87 $178.05K
Dec 08, 2025 Ra Capital Management, L.P. N/A Sale 4.18M $13.98 $58.37M
Nov 19, 2025 Robert J Gould N/A Sale 15.00K $11.03 $165.45K
May 08, 2025 Greg Tourangeau N/A Sale 498.00 $5.06 $2.52K

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
Suvretta Capital Management, LLC 6.56M Mar 31, 2026 9.85% $1.29 0.00%
RA Capital Management, LLC 6.05M Mar 31, 2026 9.09% $0.49 0.00%
BlackRock Inc 5.39M Mar 31, 2026 8.09% $0.00 26.43%
TCG Crossover Management, LLC 5.25M Mar 31, 2026 7.88% $1.15 0.00%
Vanguard Group Inc 3.56M Dec 31, 2025 5.34% $0.00 18.67%
BRAIDWELL LP 3.13M Mar 31, 2026 4.70% $0.80 2.41%
Nantahala Capital Management, LLC 3.05M Mar 31, 2026 4.58% $0.86 -28.96%
Siren, L.L.C. 2.35M Mar 31, 2026 3.53% $0.50 20.51%
First Turn Management LLC 2.26M Mar 31, 2026 3.39% $1.93 19.20%
Aberdeen Group PLC 2.21M Mar 31, 2026 3.32% $0.03 76.39%
Point72 Asset Management, L.P. 2.07M Mar 31, 2026 3.11% $0.02 -13.48%
GSK PLC 1.79M Mar 31, 2026 2.68% $2.29 0.00%
Balyasny Asset Management LLC 1.78M Mar 31, 2026 2.67% $0.02 83.42%
D. E. Shaw & Co LP 1.62M Mar 31, 2026 2.44% $0.01 -15.18%
State Street Corp 1.55M Mar 31, 2026 2.33% $0.00 54.16%
Geode Capital Management, LLC 1.49M Mar 31, 2026 2.23% $0.00 34.43%
Alyeska Investment Group, L.P. 1.33M Mar 31, 2026 1.99% $0.03 0.00%
Citadel Advisors Llc 1.29M Mar 31, 2026 1.94% $0.00 7.08%
Assenagon Asset Management SA 1.19M Mar 31, 2026 1.79% $0.01 0.00%
Dimensional Fund Advisors, Inc. 1.13M Mar 31, 2026 1.70% $0.00 7.53%

Shares Statistics

Shares Outstanding: 66.63M
Shares Float: 47.97M
% Insiders: 385.90%
% Institutions: 10,804.10%
Short % Float: 11.84%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Vanguard Total Stock Mkt Idx Inv 2.07M 3.11% ▲ 0.00% Apr 30, 2026
2 abrdn Life Sciences Investors 1.52M 2.28% ▲ 0.00% Apr 30, 2026
3 iShares Russell 2000 ETF 1.42M 2.13% ▲ 0.85% Apr 30, 2026
4 abrdn Healthcare Investors 693.45K 1.04% ▲ 0.00% Apr 30, 2026
5 Vanguard Institutional Extnd Mkt Idx Tr 552.12K 0.83% ▲ 0.55% Apr 30, 2026
6 iShares Russell 2000 Value ETF 463.48K 0.70% ▲ 0.54% Apr 30, 2026
7 iShares Biotechnology ETF 423.36K 0.64% ▲ 0.64% Apr 30, 2026
8 Fidelity Small Cap Index 422.20K 0.63% ▲ 0.99% Feb 28, 2026
9 BlackRock Advantage Small Cap Core Instl 416.77K 0.63% ▲ 244.47% Apr 30, 2026
10 State Street® SPDR® S&P® PhrmctlsETF 396.77K 0.60% ▲ 0.00% Apr 30, 2026

Valuation Metrics

Enterprise Value: $99.67M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $209.23M
EBITDA: $-85.18M
Book Value: $5.00
Earnings/Share: $-1.15
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -18.36%
ROE (TTM): -27.10%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): -100.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 27.40x 0.01x 0.05x N/A -0.03x
2024-12-31 22.63x 0.01x 0.07x N/A -0.12x
2023-12-31 17.71x 0.01x 0.09x N/A -0.02x
2022-12-31 12.41x 0.01x 0.12x -41.84x -0.02x
2021-12-31 11.77x 0.05x 0.10x -29.78x -0.12x
2020-12-31 4.23x 0.00x 0.27x N/A 0.00x
2019-12-31 8.24x 0.00x 0.21x N/A 0.00x
2018-12-31 17.52x 0.00x 0.11x N/A 0.00x
2017-12-31 0.48x 0.00x 0.70x N/A 0.00x

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