Stock Fundamentals

Company Information

Company Name
Cytokinetics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US23282W6057
CIK: 0001061983
CUSIP: 23282W100
Currency: USD
Full Time Employees: 673
Phone: 650 624 3000
Fiscal Year End: December
IPO Date: Apr 29, 2004
Description:

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction. In addition, the company is involved in developing and Ulacamten, a novel, selective, oral, and small molecule cardiac myosin inhibitor designed to reduce the hypercontractility associated with heart failure with preserved ejection fraction in Phase 1 clinical trials; and CK-089, a fast skeletal muscle troponin activator in Phase 1 clinical trials. Cytokinetics, Incorporated was incorporated in 1997 and is headquartered in South San Francisco, California.

Address:

350 Oyster Point Boulevard, South San Francisco, CA, United States, 94080

Directors & Officers

Name Title Year Born
Mr. Robert I. Blum CEO, President & Director 1964
Mr. Sung H. Lee EVP & CFO 1970
Mr. Jeffrey J. Hessekiel J.D. Executive VP, Chief Legal & Administrative Officer 1969
Dr. Fady Ibraham Malik FACC, M.D., Ph.D. Executive Vice President of Research & Development 1964
Mr. Andrew M. Callos Executive VP & Chief Commercial Officer 1969
Dr. James H. Sabry M.D., Ph.D. Co-Founder & Chairman of Scientific Advisory Board 1958
Dr. James A. Spudich Ph.D. Co-Founder & Member of Scientific Advisory Board 1942
Mr. Jeff Lotz Vice President of Sales & Operations NA
Ms. Holly Laughlin VP of Accounting & Corporate Controller NA
Mr. Steven M. Cook J.D. Senior Vice President of Global Supply Chain Operations & Technical Operations 1959

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Apr 21, 2026 Fady Ibraham Malik N/A Sale 3.50K $65.69 $229.92K
Apr 15, 2026 Robert I Blum N/A Sale 7.50K $65.38 $490.35K
Apr 15, 2026 Andrew Callos N/A Sale 7.45K $66.02 $491.78K
Apr 07, 2026 Fady Ibraham Malik N/A Sale 4.50K $65.11 $293.00K
Mar 18, 2026 Andrew Callos N/A Sale 1.93K $62.07 $119.80K
Mar 17, 2026 Andrew Callos N/A Sale 8.54K $62.15 $530.89K
Mar 17, 2026 Fady Ibraham Malik N/A Sale 12.03K $62.15 $747.85K
Mar 17, 2026 Robert I Blum N/A Sale 36.60K $62.15 $2.27M
Mar 17, 2026 Sung Lee N/A Sale 4.94K $62.15 $306.71K
Mar 16, 2026 Andrew Callos N/A Sale 1.71K $61.03 $104.30K
Mar 09, 2026 Andrew Callos N/A Sale 2.58K $60.72 $156.78K
Mar 09, 2026 Robert I Blum N/A Sale 7.93K $60.72 $481.57K
Mar 09, 2026 Fady Ibraham Malik N/A Sale 2.91K $60.72 $176.51K
Mar 05, 2026 Andrew Callos N/A Sale 26.00K $61.87 $1.61M
Feb 05, 2026 Andrew Callos N/A Sale 15.00K $61.93 $928.95K
Feb 02, 2026 Andrew Callos N/A Sale 886.00 $62.10 $55.02K
Jan 05, 2026 Andrew Callos N/A Sale 15.00K $60.28 $904.20K
Jan 02, 2026 Andrew Callos N/A Sale 1.80K $62.62 $112.59K
Dec 29, 2025 Andrew Callos N/A Sale 1.81K $62.44 $112.95K
Dec 22, 2025 Wendell Wierenga N/A Sale 20.00K $66.14 $1.32M

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
T. Rowe Price Investment Management,Inc. 17.52M Mar 31, 2026 12.91% $0.80 -35.35%
BlackRock Inc 16.55M Mar 31, 2026 12.19% $0.02 0.93%
Vanguard Group Inc 12.05M Dec 31, 2025 8.87% $0.01 1.61%
FMR Inc 10.72M Mar 31, 2026 7.90% $0.04 -16.28%
Wellington Management Company LLP 8.01M Mar 31, 2026 5.90% $0.10 0.91%
Vanguard Portfolio Management, LLC 5.84M Mar 31, 2026 4.30% $0.02 0.00%
State Street Corp 5.75M Mar 31, 2026 4.23% $0.01 -1.38%
Vanguard Capital Management, LLC 5.49M Mar 31, 2026 4.04% $0.01 0.00%
venBio Select Advisor LLC 3.33M Mar 31, 2026 2.46% $2.16 0.00%
Geode Capital Management, LLC 3.22M Mar 31, 2026 2.37% $0.01 5.22%
Bank of America Corp 3.13M Mar 31, 2026 2.30% $0.02 6.27%
RTW INVESTMENTS, LLC 2.72M Mar 31, 2026 2.00% $1.78 0.00%
The Goldman Sachs Group Inc 2.21M Mar 31, 2026 1.62% $0.02 -7.00%
UBS Group AG 2.08M Mar 31, 2026 1.53% $0.02 83.59%
Polar Capital Holdings PLC 1.66M Mar 31, 2026 1.22% $0.39 -31.43%
Integral Health Asset Management, LLC 1.60M Mar 31, 2026 1.18% $5.04 14.29%
T. Rowe Price Associates, Inc. 1.58M Mar 31, 2026 1.17% $0.01 -17.92%
Morgan Stanley - Brokerage Accounts 1.51M Mar 31, 2026 1.11% $0.01 18.95%
Paradigm Biocapital Advisors LP 1.48M Mar 31, 2026 1.09% $1.99 0.00%
Northern Trust Corp 1.44M Mar 31, 2026 1.06% $0.01 4.41%

Shares Statistics

Shares Outstanding: 135.77M
Shares Float: 123.87M
% Insiders: 70.20%
% Institutions: 11,880.10%
Short % Float: 17.65%

Fund Holdings

Rank Holder Name Shares Held % of Shares Change Date Reported
1 T. Rowe Price Capital Appreciation 5.11M 3.76% ▲ 0.00% Apr 30, 2026
2 iShares Core S&P Mid-Cap ETF 4.48M 3.30% ▲ 0.02% May 29, 2026
3 Vanguard Health Care Inv 4.06M 2.99% ▲ 0.35% Mar 31, 2026
4 Vanguard Total Stock Mkt Idx Inv 3.93M 2.89% ▲ 0.58% Apr 30, 2026
5 iShares Russell 2000 ETF 3.10M 2.28% ▲ 0.93% May 29, 2026
6 Vanguard Small Cap Index 2.84M 2.09% ▼ 0.21% Apr 30, 2026
7 Fidelity OTC 2.27M 1.67% ▲ 0.00% Apr 30, 2026
8 American Funds SMALLCAP World A 2.11M 1.56% ▲ 79.41% Mar 31, 2026
9 T. Rowe Price US Mid-Cap Growth Equity 1.69M 1.24% ▼ 10.67% Mar 31, 2026
10 T. Rowe Price Mid-Cap Growth 1.69M 1.24% ▼ 0.04% Apr 30, 2026

Valuation Metrics

Enterprise Value: $9.35B
Trailing P/E: 0.00
Forward P/E: 117.65

Financial Highlights

Market Cap: $9.52B
EBITDA: $-629.04M
PEG Ratio: $-0.42
Book Value: $-6.65
Earnings/Share: $-6.85
Profit Margin: 0.00%
Operating Margin: -948.69%
ROA (TTM): -31.54%
ROE (TTM): -572.15%
Revenue (TTM): $105.82M
Revenue/Share (TTM): $0.87
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 1,125.80%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2025-12-31 4.53x -1.78x 1.46x -5.89x -1.52x
2024-12-31 6.17x -4.99x 1.10x -6.20x -1.37x
2023-12-31 6.12x -1.64x 1.47x -8.60x -1.39x
2022-12-31 9.40x -0.72x 1.11x -6.34x -0.24x
2021-12-31 7.45x 0.26x 0.71x -6.35x -0.35x
2020-12-31 15.20x 0.43x 0.79x -2.43x -0.56x
2019-12-31 8.98x -4.54x 1.04x -3.61x -0.53x
2018-12-31 9.36x 1.64x 0.88x -4.12x -0.51x
2017-12-31 8.45x 0.34x 0.63x -6.67x -0.34x
2016-12-31 4.77x 0.32x 0.45x 8.36x 1.54x
2015-12-31 3.57x 0.25x 0.40x -397.95x -0.46x
2014-12-31 5.50x 0.01x 0.31x -136.61x -0.10x
2013-12-31 2.97x 0.07x 0.35x -191.49x -0.11x
2012-12-31 13.29x 0.02x 0.08x -19,551.00x -0.03x
2011-12-31 11.14x 0.00x 0.09x -461.19x 0.00x
2010-12-31 10.04x 0.01x 0.10x -304.51x -0.02x
2009-12-31 5.79x 0.03x 0.17x 63.80x 0.10x
2008-12-31 2.58x 0.09x 0.43x -120.32x -0.09x
2007-12-31 4.61x 0.09x 0.36x -80.81x -0.19x
2006-12-31 5.82x 0.10x 0.37x -117.28x -0.20x
2005-12-31 7.00x 0.13x 0.20x -83.43x -0.24x
2004-12-31 9.88x 0.10x 0.16x -70.01x -0.31x
2003-12-31 3.92x -0.11x 2.46x -13.09x -0.34x
2002-12-31 2.98x -0.16x 2.08x -18.02x -0.45x
2001-12-31 N/A 0.00x 1.47x -41.99x 0.00x
2000-12-31 N/A 0.00x 1.36x -51.66x 0.00x

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