CBIO
Crescent Biopharma, Inc.

CBIO.US crescentbiopharma.com + Research + Basket
Healthcare · Biotechnology
ISIN KYG2545C1042
Employees 69
Phone 617 460 5595
Fiscal year end December
IPO Jan 10, 2014
Address 300 Fifth Avenue, Waltham, MA, United States, 02451
13.22
-0.05 (-0.38%)
USD · NASDAQ
52-week range
8.72
27.41
Trading at 24% of the 52-week range
Market Cap
492.94M
P/E Ratio
0.00
Forward P/E
0.00
Book Value
4.77
Div. Yield
N/A
% Institutions
82.83%
% Insiders
0.268%
1 Year

+2.1%
3 Year

-89.8%
10 Year

-97.8%
Description
Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. for the development and commercialization of oncology therapeutics. The company was formerly known as GlycoMimetics, Inc. The company was founded in 2024 and is headquartered in Waltham, Massachusetts.
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People

▼
Directors & Officers

Name	Title	Year Born
Mr. Joshua T. Brumm	CEO & Director	1978
Dr. Jonathan McNeill M.D.	President & COO	1985
Dr. Ellie Im M.D.	Chief Medical Officer	1978
Mr. Richard William Scalzo M.B.A.	Chief Financial Officer	1986
Mr. Ryan Lynch	Senior VP of Finance, Treasurer & Chief Accounting Officer	1984
Dr. Wenjie Cheng Ph.D.	Senior Vice President of Technical Operations	NA
Dr. Jan Pinkas Ph.D.	Chief Scientific Officer	1969
Ms. Barbara Bispham Hale J.D.	General Counsel & Corporate Secretary	1987
Ms. Amy Reilly	Chief Communications Officer	1974
Mr. Christopher Doughty	Chief Business Officer	1988
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Dec 04, 2025	Fairmount Funds Management Llc	N/A	Purchase	1.36M	$13.41	$18.24M	SEC
Shareholders

▼
Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
FMR Inc	4.13M	Jun 30, 2026	11.13%	$0.00	0.00%
Bvf Inc	2.75M	Jun 30, 2026	7.40%	$1.27	0.00%
Fairmount Funds Management LLC	2.75M	Jun 30, 2026	7.40%	$3.27	0.00%
VR Adviser, LLC	2.13M	Jun 30, 2026	5.74%	$1.16	0.00%
Logos Global Management LP	1.90M	Jun 30, 2026	5.11%	$1.47	293.78%
FCPM III SERVICES BV	1.68M	Jun 30, 2026	4.52%	$4.02	0.00%
Balyasny Asset Management LLC	1.66M	Jun 30, 2026	4.48%	$0.04	10.12%
Vestal Point Capital LP	1.63M	Jun 30, 2026	4.39%	$0.69	8.67%
Opaleye Management Inc	1.32M	Jun 30, 2026	3.55%	$2.15	0.51%
BlackRock Inc	1.27M	Jun 30, 2026	3.42%	$0.00	998.95%
TANG CAPITAL MANAGEMENT LLC	1.16M	Jun 30, 2026	3.12%	$0.95	0.00%
Vanguard Capital Management, LLC	767.76K	Jun 30, 2026	2.07%	$0.00	-4.20%
Boxer Capital Management, LLC	453.69K	Jun 30, 2026	1.22%	$0.62	0.00%
Millennium Management LLC	403.86K	Jun 30, 2026	1.09%	$0.00	24.82%
Geode Capital Management, LLC	384.58K	Jun 30, 2026	1.04%	$0.00	269.00%
Jennison Associates LLC	378.51K	Jun 30, 2026	1.02%	$0.00	147.43%
NEXTBio Capital Management LP	372.86K	Jun 30, 2026	1.00%	$3.09	0.00%
RTW INVESTMENTS, LLC	372.86K	Jun 30, 2026	1.00%	$0.06	0.00%
Remedium Capital Partners, LLC	361.25K	Jun 30, 2026	0.97%	$1.44	0.00%
State Street Corp	315.59K	Jun 30, 2026	0.85%	$0.00	707.81%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Fidelity Small Cap Growth	950.82K	2.56%	▲ 83.37%	Jul 31, 2026
2	Fidelity Growth Company Fund	939.16K	2.53%	▲ 221.28%	Aug 31, 2026
3	Vanguard MStar Total Stk Mkt Idx Invest	906.65K	2.44%	▲ 0.00%	Sep 30, 2026
4	iShares Russell 2000 ETF	738.08K	1.99%	▼ 1.14%	Sep 30, 2026
5	Fidelity Small Cap Growth K6	461.30K	1.24%	▲ 92.36%	Jul 31, 2026
6	Fidelity Advisor Biotechnology I	456.59K	1.23%	▲ 28.22%	Aug 31, 2026
7	Fidelity Select Biotechnology	339.56K	0.91%	▲ 78.32%	Aug 31, 2026
8	State Street® SPDR® S&P® Biotech ETF	334.66K	0.90%	▼ 1.88%	Sep 30, 2026
9	PGIM Jennison Health Sciences Z	311.39K	0.84%	▲ 0.00%	Sep 30, 2026
10	Fidelity Select Health Care	308.25K	0.83%	▲ 2.12%	Aug 31, 2026
Financial Highlights

▼
Market Cap: $492.94M
EBITDA: $-170.03M
Book Value: $4.77
Earnings/Share: $-7.63
Profit Margin: 0.00%
Operating Margin: -1,432.64%
ROA (TTM): -69.15%
ROE (TTM): -160.75%
Revenue (TTM): $11.88M
Revenue/Share (TTM): $0.43
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%
Valuation Metrics

Enterprise Value: $307.84M
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 37.14M
Shares Float: 27.03M
% Insiders: 0.268%
% Institutions: 82.83%
Short % Float: 22.07%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

▼
Line Item
Step Type
Value
Revenue
adjust
$10.84M
Cost of Goods Sold
adjust
$-84.00K
Gross Profit
subtotal
$10.84M
SG&A
adjust
$-25.39M
R&D
adjust
$-138.09M
Operating Income
subtotal
$-152.63M
Other / Non-Operating Items
adjust
$-1.31M
Net Income
subtotal
$-153.94M
Earnings Per Share (EPS) History

▼
Financial Ratios

▼
📦 Raw API Data (JSON Explorer)

▼
Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "CBIO",
        "Type": "Common Stock",
        "Name": "Crescent Biopharma, Inc.",
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Crescent Biopharma, Inc.

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