Stock Fundamentals

Company Information

Company Name
Astria Therapeutics Inc
Sector
Healthcare
Industry
Biotechnology
Exchange
NASDAQ
ISIN: US04635X1028
CIK: 0001454789
CUSIP: 04635X102
Currency: USD
Full Time Employees: 78
Phone: 617 349 1971
Fiscal Year End: December
IPO Date: Jun 25, 2015
Description:

Astria Therapeutics, Inc., a biopharmaceutical company, engages in the discovery, development, and commercialization of therapeutics for allergic and immunological diseases in the United States. Its lead product candidate is navenibart, a monoclonal antibody inhibitor of plasma kallikrein, which is in Phase 1b/2 clinical trials for the treatment of hereditary angioedema. The company is also developing STAR-0310, a monoclonal antibody OX40 antagonist that is in clinical development for the treatment of atopic dermatitis, an immune disorder associated with loss of skin barrier function and itching. The company was formerly known as Catabasis Pharmaceuticals, Inc. and changed its name to Astria Therapeutics, Inc. in September 2021. Astria Therapeutics, Inc. was incorporated in 2008 and is headquartered in Boston, Massachusetts. As of January 23, 2026, Astria Therapeutics, Inc. operates as a subsidiary of BioCryst Pharmaceuticals, Inc.

Address:

22 Boston Wharf Road, Boston, MA, United States, 02210

Directors & Officers

Name Title Year Born
Ms. Jill C. Milne Ph.D. Co-Founder, CEO, President & Director 1968
Ms. Keri McGrail Chief Human Resources Officer NA
Mr. John Ruesch Senior Vice President of Pharmaceutical Sciences & Technical Operations NA
Ms. Rafif Dagher Senior VP and Head of Discovery, Nonclinical Development & Translational Research NA

Institutional Holders

Holder Name Shares Date Reported % Out Value % Change
Perceptive Advisors LLC 6.49M Sep 30, 2025 11.36% $1.36 0.00%
FCPM III SERVICES BV 4.11M Sep 30, 2025 7.20% $5.98 0.00%
BlackRock Inc 3.49M Sep 30, 2025 6.11% $0.00 -5.69%
JPMorgan Chase & Co 3.36M Sep 30, 2025 5.89% $0.00 98.18%
Millennium Management LLC 3.03M Sep 30, 2025 5.32% $0.01 2.18%
TCG Crossover Management, LLC 2.76M Sep 30, 2025 4.84% $0.99 0.00%
Vanguard Group Inc 2.62M Dec 31, 2025 4.60% $0.00 -0.72%
Balyasny Asset Management LLC 1.64M Dec 31, 2025 2.87% $0.03 0.00%
Nantahala Capital Management, LLC 1.07M Dec 31, 2025 1.87% $0.46 0.00%
Man Group PLC 977.20K Dec 31, 2025 1.71% $0.02 0.00%
Geode Capital Management, LLC 958.24K Sep 30, 2025 1.68% $0.00 -0.59%
Adage Capital Partners Gp LLC 900.00K Dec 31, 2025 1.58% $0.02 7.91%
State Street Corp 890.67K Sep 30, 2025 1.56% $0.00 -4.65%
Squarepoint Ops LLC 882.79K Dec 31, 2025 1.55% $0.01 5,703.64%
Tudor Investment Corp Et AL 875.00K Dec 31, 2025 1.53% $0.02 0.00%
Soros Fund Management LLC 873.40K Dec 31, 2025 1.53% $0.13 0.00%
Morgan Stanley - Brokerage Accounts 864.41K Sep 30, 2025 1.51% $0.00 64.48%
Citadel Advisors Llc 848.98K Sep 30, 2025 1.49% $0.00 -27.75%
First Trust Capital Management L.P. 831.36K Dec 31, 2025 1.46% $0.66 0.00%
Point72 Asset Management, L.P. 749.94K Sep 30, 2025 1.31% $0.01 -1.68%

Shares Statistics

Shares Outstanding: 57.08M
Shares Float: 39.18M
% Insiders: 48.10%
% Institutions: 9,489.80%
Short % Float: 12.65%

🏆 Top 10 Institutional Holders

Rank Holder Name Shares Held % of Shares Change Date Reported
1 Perceptive Advisors LLC 6.49M 11.36% ▲ 0.00% Sep 30, 2025
2 FCPM III SERVICES BV 4.11M 7.20% ▲ 0.00% Sep 30, 2025
3 BlackRock Inc 3.49M 6.11% ▼ 5.69% Sep 30, 2025
4 JPMorgan Chase & Co 3.36M 5.89% ▲ 98.18% Sep 30, 2025
5 Millennium Management LLC 3.03M 5.32% ▲ 2.18% Sep 30, 2025
6 TCG Crossover Management, LLC 2.76M 4.84% ▲ 0.00% Sep 30, 2025
7 Vanguard Group Inc 2.62M 4.60% ▼ 0.72% Dec 31, 2025
8 Balyasny Asset Management LLC 1.64M 2.87% ▲ 0.00% Dec 31, 2025
9 Nantahala Capital Management, LLC 1.07M 1.87% ▲ 0.00% Dec 31, 2025
10 Man Group PLC 977.20K 1.71% ▲ 0.00% Dec 31, 2025

Valuation Metrics

Enterprise Value: $590.19M
Trailing P/E: 0.00
Forward P/E: 0.00

Financial Highlights

Market Cap: $718.13M
EBITDA: $-32.38M
Book Value: $2.44
Earnings/Share: $-2.14
Profit Margin: 0.00%
Operating Margin: -4,830.60%
ROA (TTM): -26.94%
ROE (TTM): -43.15%
Revenue (TTM): $706.00K
Revenue/Share (TTM): $0.01
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%

Stock Price History

1 Year Price History

2 Years Price History

5 Years Price History

10 Years Price History

Download Financials (Excel)

Financial Charts

Revenue & Net Income (Yearly)

Revenue & Net Income (Quarterly)

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Earnings Per Share (EPS) History

Financial Ratios (Yearly)

Financial Ratios (Quarterly)

Earnings History

Balance Sheet (Yearly)

Financial Ratios

Date Current Ratio Debt/Equity Debt/Assets Interest Coverage Debt/EBITDA
2024-12-31 17.49x 0.00x 0.07x N/A -0.01x
2023-12-31 21.73x 0.00x 0.05x N/A 0.00x
2022-12-31 25.13x 0.00x 0.04x -32.06x -0.01x
2021-12-31 24.42x 0.00x 0.04x -3,046.50x -0.01x
2020-12-31 7.25x 0.02x 0.14x -158.62x -0.02x
2019-12-31 7.74x 0.03x 0.15x N/A -0.05x
2018-12-31 9.33x 0.00x 0.11x -263.71x 0.00x
2017-12-31 2.90x 0.21x 0.34x -58.65x -0.09x
2016-12-31 4.75x 0.11x 0.28x -42.48x -0.09x
2015-12-31 8.14x 0.06x 0.21x -32.37x -0.10x
2014-12-31 3.55x 0.00x 5.58x -105.25x -0.01x
2013-12-31 10.44x 0.00x 2.68x N/A 0.00x
2012-12-31 2.97x 0.00x 0.32x N/A 0.00x

Insider Trading

Date Insider Name Title Transaction Type Shares Price Value
Feb 01, 2024 Perceptive Advisors Llc N/A Purchase 2.48M $12.09 $30.00M
Jan 29, 2024 Christopher Morabito N/A Sale 9.20K $11.15 $102.58K
Jan 26, 2024 Christopher Morabito N/A Sale 800.00 $11.02 $8.82K
Dec 21, 2023 Perceptive Advisors Llc N/A Purchase 740.00K $6.20 $4.59M
Oct 16, 2023 Perceptive Advisors Llc N/A Purchase 1.07M $6.51 $7.00M

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