ANNX.US Fundamentals - AlphaKey Financial

People

▼
Directors & Officers

Name	Title	Year Born
Mr. Douglas E. Love Esq., J.D.	CEO, President & Director	1968
Ms. Jennifer Lew CPA	Executive VP, CFO & Corporate Secretary	1973
Dr. Ted Yednock Ph.D.	Executive VP, Chief Innovation Officer & Chairman of the Scientific Advisory Board	1958
Dr. Dean R. Artis Ph.D.	Chief Scientific Officer & Executive VP	1961
Ms. Linda A. Fitzpatrick	Chief Human Resources Officer	1957
Mr. Michael Overdorf M.B.A.	Executive VP & Chief Business Officer	1971
Mr. Henk-Andre Kroon M.D.	Senior Vice President of Translational Medicine	NA
Dr. Jamie Dananberg M.D.	Executive VP & Chief Medical Officer	1958
Mr. Shikhar Agarwal M.B.A.	Senior VP & Head of Commercial	NA
Dr. Sunil Mehta Pharm.D.	Senior VP of Medical Affairs	NA
Insider Trading

Open insider trading
Date	Insider Name	Title	Transaction Type	Shares	Price	Value	SEC
Apr 10, 2026	William H Carson	N/A	Purchase	8.00K	$6.20	$49.60K	SEC
Mar 10, 2026	William H Carson	N/A	Purchase	8.00K	$5.67	$45.36K	SEC
Feb 18, 2026	Dean Richard Artis	N/A	Sale	5.29K	$5.10	$26.98K	SEC
Feb 18, 2026	Jamie Dananberg	N/A	Sale	5.29K	$5.10	$26.98K	SEC
Feb 18, 2026	Jennifer Lew	N/A	Sale	7.85K	$5.11	$40.12K	SEC
Feb 18, 2026	Michael Overdorf	N/A	Sale	6.23K	$5.10	$31.75K	SEC
Feb 18, 2026	Ted Yednock	N/A	Sale	7.86K	$5.11	$40.15K	SEC
Dec 30, 2025	William H Carson	N/A	Purchase	4.12K	$5.02	$20.66K	SEC
Dec 01, 2025	Jung Choi	N/A	Purchase	33.00K	$4.19	$138.27K	SEC
Dec 01, 2025	William H Carson	N/A	Purchase	4.12K	$4.47	$18.39K	SEC
Nov 21, 2025	Muneer A Satter	N/A	Purchase	422.61K	$4.28	$1.81M	SEC
Nov 20, 2025	Muneer A Satter	N/A	Purchase	400.00K	$4.48	$1.79M	SEC
Nov 19, 2025	Muneer A Satter	N/A	Purchase	500.00K	$3.94	$1.97M	SEC
Nov 17, 2025	Muneer A Satter	N/A	Purchase	500.00K	$2.99	$1.50M	SEC
Oct 30, 2025	William H Carson	N/A	Purchase	4.12K	$3.17	$13.04K	SEC
Sep 30, 2025	William H Carson	N/A	Purchase	4.12K	$3.05	$12.55K	SEC
Jul 30, 2025	William H Carson	N/A	Purchase	4.12K	$2.43	$10.00K	SEC
Jul 14, 2025	Jennifer Lew	N/A	Sale	1.12K	$2.58	$2.88K	SEC
Jul 14, 2025	Jennifer Lew	N/A	Sale	1.12K	$2.58	$2.88K	SEC
Jul 14, 2025	Michael Overdorf	N/A	Sale	853.00	$2.61	$2.23K	SEC
Shareholders

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Institutional Holders

Holder Name	Shares	Date Reported	% Out	Value	% Change
FMR Inc	19.52M	Jun 30, 2026	10.30%	$0.00	83.52%
BlackRock Inc	13.54M	Jun 30, 2026	7.14%	$0.00	23.78%
Redmile Group, LLC	11.87M	Jun 30, 2026	6.26%	$4.55	-18.42%
State Street Corp	9.82M	Jun 30, 2026	5.18%	$0.00	41.99%
Bvf Inc	8.70M	Jun 30, 2026	4.59%	$1.27	0.00%
Woodline Partners LP	6.93M	Jun 30, 2026	3.65%	$0.12	196.31%
Vanguard Capital Management, LLC	6.87M	Jun 30, 2026	3.62%	$0.00	15.35%
Mak Capital One LLC	5.86M	Jun 30, 2026	3.09%	$4.69	24.09%
The Goldman Sachs Group Inc	5.83M	Jun 30, 2026	3.07%	$0.00	170.59%
Siren, L.L.C.	4.46M	Jun 30, 2026	2.35%	$0.52	12.63%
Bain Capital Life Sciences Investors, LLC	4.44M	Jun 30, 2026	2.34%	$1.51	-14.87%
Bellevue Group AG	4.10M	Jun 30, 2026	2.16%	$0.49	-20.50%
Geode Capital Management, LLC	4.04M	Jun 30, 2026	2.13%	$0.00	19.52%
MPM Oncology Impact Management LP	3.54M	Jun 30, 2026	1.87%	$1.23	0.00%
Ameriprise Financial Inc	3.51M	Jun 30, 2026	1.85%	$0.00	1.75%
Great Point Partners LLC	3.50M	Jun 30, 2026	1.85%	$3.78	40.00%
Adage Capital Partners Gp LLC	3.50M	Jun 30, 2026	1.85%	$0.03	-18.60%
Morgan Stanley - Brokerage Accounts	3.14M	Jun 30, 2026	1.66%	$0.00	14.93%
Palo Alto Investors, LLC	2.95M	Jun 30, 2026	1.56%	$2.33	0.00%
Balyasny Asset Management LLC	2.83M	Jun 30, 2026	1.49%	$0.02	-27.17%
Fund Holdings

Rank	Holder Name	Shares Held	% of Shares	Change	Date Reported
1	Fidelity Select Biotechnology	6.17M	3.26%	▲ 0.00%	Aug 31, 2026
2	State Street® SPDR® S&P® Biotech ETF	5.89M	3.10%	▼ 1.88%	Sep 30, 2026
3	Vanguard MStar Total Stk Mkt Idx Invest	5.72M	3.02%	▲ 15.10%	Sep 30, 2026
4	iShares Russell 2000 ETF	4.08M	2.15%	▼ 1.14%	Sep 30, 2026
5	Fidelity Stock Selector Small Cap	2.07M	1.09%	▲ 27.57%	Jul 31, 2026
6	Columbia Acorn Inst	1.82M	0.96%	▲ 0.00%	Aug 31, 2026
7	Fidelity Small Cap Growth	1.79M	0.94%	▲ 44.14%	Jul 31, 2026
8	Fidelity Small Cap Index	1.70M	0.89%	▲ 0.70%	Jul 31, 2026
9	Fidelity Advisor Biotechnology I	1.66M	0.88%	▲ 0.00%	Aug 31, 2026
10	iShares Russell 2000 Growth ETF	1.47M	0.78%	▼ 0.13%	Sep 30, 2026
Financial Highlights

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Market Cap: $712.82M
EBITDA: $-208.39M
Book Value: $1.07
Earnings/Share: $-1.13
Profit Margin: 0.00%
Operating Margin: 0.00%
ROA (TTM): -51.54%
ROE (TTM): -105.26%
Revenue (TTM): $0.00
Revenue/Share (TTM): $0.00
Earnings Growth (YOY): 0.00%
Revenue Growth (YOY): 0.00%
Valuation Metrics

Enterprise Value: $516.85M
Trailing P/E: 0.00
Forward P/E: 0.00
Shares Statistics

Shares Outstanding: 189.58M
Shares Float: 163.76M
% Insiders: 0.438%
% Institutions: 103.45%
Short % Float: 17.87%
Stock Price History

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1 Year Price History

3 Years Price History

10 Years Price History

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Financial Charts

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Open balance sheet Open capital intensity Download Financials (Excel)
Revenue, Net Income & Operating Cash Flow (Yearly)

Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

Change % vs Prior Quarter

Operating Expenses (Yearly)

Operating Expenses (Quarterly)

Balance Sheet (Yearly)

Balance Sheet (Quarterly)

Assets Breakdown (Yearly)

Assets Breakdown (Quarterly)

Liabilities Breakdown (Yearly)

Liabilities Breakdown (Quarterly)

Income Statement Waterfall

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Line Item
Step Type
Value
Revenue
adjust
$0.00
Cost of Goods Sold
adjust
$-3.69M
Gross Profit
subtotal
$-3.69M
SG&A
adjust
$-31.71M
R&D
adjust
$-184.70M
Operating Income
subtotal
$-216.41M
Other / Non-Operating Items
adjust
$9.72M
Net Income
subtotal
$-206.69M
Earnings Per Share (EPS) History

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Financial Ratios

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📦 Raw API Data (JSON Explorer)

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Comprehensive raw data returned from the EOD Fundamentals API. Expand sections below to drill down.
{
    "General": {
        "Code": "ANNX",
        "Type": "Common Stock",
        "Name": "Annexon\u00a0Inc",
        "Exchange": "NASDAQ",
        "OperatingMIC": "XNAS",
        "CurrencyCode": "USD",
        "CurrencyName": "US Dollar",
        "CurrencySymbol": "$",
        "CountryName": "USA",
        "CountryISO": "US",
        "OpenFigi": "BBG007QVDFG2",
        "ISIN": null,
        "LEI": null,
        "PrimaryTicker": "ANNX.US",
        "CUSIP": null,
        "CIK": "0001528115",
        "EmployerIdNumber": null,
        "FiscalYearEnd": "December",
        "IPODate": "2020-07-24",
        "InternationalDomestic": null,
        "Sector": "Healthcare",
        "Industry": "Biotechnology",
        "GicSector": "Health Care",
        "GicGroup": "Pharmaceuticals, Biotechnology & Life Sciences",
        "GicIndustry": "Biotechnology",
        "GicSubIndustry": "Biotechnology",
        "HomeCategory": null,
        "IsDelisted": false,
        "Description": "Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines for treating inflammatory-related diseases. The company provides Tanruprubart, an investigational full-length monoclonal antibody, which is in Phase 3 clinical trial for the treatment of patients with guillain-barr\u00e9 syndrome; completed Phase II clinical trial for treating Huntington's disease; and in Phase 2a clinical trial for the treatment of amyotrophic lateral sclerosis. It is also developing ANX007, an antigen-binding fragment (Fab) that is in Phase 3 program for the treatment of patients with geographic atrophy; and ANX1502, a novel oral small molecule inhibitor, which is in Phase 1 clinical trials for autoimmune indications. In addition, it develops ANX009, a C1q-blocking Fab that is in Phase I clinical trial for treating patients with lupus nephritis. The company was incorporated in 2011 and is headquartered in Brisbane, California.",
        "Address": "1400 Sierra Point Parkway, Brisbane, CA, United States, 94005",
        "AddressData": {
            "Street": "1400 Sierra Point Parkway",
            "City": "Brisbane",
            "State": "CA",
            "Country": "United States",
            "ZIP": "94005"
        },
        "Listings": [],
        "Officers": [
            {
                "Name": "Mr. Douglas E. Love Esq., J.D.",
                "Title": "CEO, President & Director",
                "YearBorn": "1968"
            },
            {
                "Name": "Ms. Jennifer  Lew CPA",
                "Title": "Executive VP, CFO & Corporate Secretary",
                "YearBorn": "1973"
            },
            {
                "Name": "Dr. Ted  Yednock Ph.D.",
                "Title": "Executive VP, Chief Innovation Officer & Chairman of the Scientific Advisory Board",
                "YearBorn": "1958"
            },
            {
                "Name": "Dr. Dean R. Artis Ph.D.",
                "Title": "Chief Scientific Officer & Executive VP",
                "YearBorn": "1961"
            },
            {
                "Name": "Ms. Linda A. Fitzpatrick",
                "Title": "Chief Human Resources Officer",
                "YearBorn": "1957"
            },
            {
                "Name": "Mr. Michael  Overdorf M.B.A.",
                "Title": "Executive VP & Chief Business Officer",
                "YearBorn": "1971"
            },
            {
                "Name": "Mr. Henk-Andre  Kroon M.D.",
                "Title": "Senior Vice President of Translational Medicine",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Jamie  Dananberg M.D.",
                "Title": "Executive VP & Chief Medical Officer",
                "YearBorn": "1958"
            },
            {
                "Name": "Mr. Shikhar  Agarwal M.B.A.",
                "Title": "Senior VP & Head of Commercial",
                "YearBorn": "NA"
            },
            {
                "Name": "Dr. Sunil  Mehta Pharm.D.",
                "Title": "Senior VP of Medical Affairs",
                "YearBorn": "NA"
            }
        ],
        "Phone": "650 822 5500",
        "WebURL": "https://www.annexonbio.com",
        "LogoURL": "/img/logos/US/ANNX.png",
        "FullTimeEmployees": 92,
        "UpdatedAt": "2026-10-28"
    },
    "Highlights": {
        "MarketCapitalization": 712817536,
        "MarketCapitalizationMln": 712.8175,
        "EBITDA": -208388000,
        "PERatio": null,
        "PEGRatio": null,
        "WallStreetTargetPrice": 17,
        "BookValue": 1.066,
        "DividendShare": null,
        "DividendYield": null,
        "EarningsShare": -1.13,
        "EPSEstimateCurrentYear": -1.0547,
        "EPSEstimateNextYear": -1.0733,
        "EPSEstimateNextQuarter": -0.2554,
        "EPSEstimateCurrentQuarter": -0.2554,
        "MostRecentQuarter": "2026-06-30",
        "ProfitMargin": 0,
        "OperatingMarginTTM": 0,
        "ReturnOnAssetsTTM": -0.5154,
        "ReturnOnEquityTTM": -1.0526,
        "RevenueTTM": 0,
        "RevenuePerShareTTM": 0,
        "QuarterlyRevenueGrowthYOY": 0,
        "GrossProfitTTM": 0,
        "DilutedEpsTTM": -1.13,
        "QuarterlyEarningsGrowthYOY": 0
    },
    "Valuation": {
        "TrailingPE": 0,
        "ForwardPE": 0,
        "PriceSalesTTM": 0,
        "PriceBookMRQ": 3.7649,
        "EnterpriseValue": 516850795,
        "EnterpriseValueRevenue": 0,
        "EnterpriseValueEbitda": -2.4694
    },
    "SharesStats": {
        "SharesOutstanding": 189579134,
        "SharesFloat": 163760352,
        "PercentInsiders": 0.438,
        "PercentInstitutions": 103.44500000000001,
        "SharesShort": null,
        "SharesShortPriorMonth": null,
        "ShortRatio": null,
        "ShortPercentOutstanding": null,
        "ShortPercentFloat": 0.1787
    },
    "Technicals": {
        "Beta": 1.328,
        "52WeekHigh": 7.18,
        "52WeekLow": 2.54,
        "50DayMA": 4.2816,
        "200DayMA": 5.2516,
        "SharesShort": 31627401,
        "SharesShortPriorMonth": 32009914,
        "ShortRatio": 9.94,
        "ShortPercent": 0.1787
    },
    "SplitsDividends": {
        "ForwardAnnualDividendRate": 0,
        "ForwardAnnualDividendYield": 0,
        "PayoutRatio": 0,
        "DividendDate": null,
        "ExDividendDate": null,
        "LastSplitFactor": "",
        "LastSplitDate": "0000-00-00",
        "NumberDividendsByYear": []
    },
    "AnalystRatings": {
        "Rating": 4.4,
        "TargetPrice": 17,
        "StrongBuy": 6,
        "Buy": 2,
        "Hold": 2,
        "Sell": 0,
        "StrongSell": 0
    },
    "Holders": {
        "Institutions": [
            {
                "name": "FMR Inc",
                "date": "2026-06-30",
                "totalShares": 10.2957,
                "totalAssets": 0.0048,
                "currentShares": 19518496,
                "change": 8882848,
                "change_p": 83.5196
            },
            {
                "name": "BlackRock Inc",
                "date": "2026-06-30",
                "totalShares": 7.142,
                "totalAssets": 0.0012,
                "currentShares": 13539744,
                "change": 2601235,
                "change_p": 23.7805
            },
            {
                "name": "Redmile Group, LLC",
                "date": "2026-06-30",
                "totalShares": 6.2612,
                "totalAssets": 4.5503,
                "currentShares": 11869877,
                "change": -2679891,
                "change_p": -18.4188
            },
            {
                "name": "State Street Corp",
                "date": "2026-06-30",
                "totalShares": 5.1822,
                "totalAssets": 0.0017,
                "currentShares": 9824321,
                "change": 2905066,
                "change_p": 41.9852
            },
            {
                "name": "Bvf Inc",
                "date": "2026-06-30",
                "totalShares": 4.5881,
                "totalAssets": 1.2699,
                "currentShares": 8698173,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Woodline Partners LP",
                "date": "2026-06-30",
                "totalShares": 3.6529,
                "totalAssets": 0.1222,
                "currentShares": 6925067,
                "change": 4587930,
                "change_p": 196.3056
            },
            {
                "name": "Vanguard Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 3.6244,
                "totalAssets": 0.0008,
                "currentShares": 6871015,
                "change": 914426,
                "change_p": 15.3515
            },
            {
                "name": "Mak Capital One LLC",
                "date": "2026-06-30",
                "totalShares": 3.0922,
                "totalAssets": 4.6895,
                "currentShares": 5862180,
                "change": 1138137,
                "change_p": 24.0924
            },
            {
                "name": "The Goldman Sachs Group Inc",
                "date": "2026-06-30",
                "totalShares": 3.0729,
                "totalAssets": 0.0029,
                "currentShares": 5825579,
                "change": 3672699,
                "change_p": 170.5947
            },
            {
                "name": "Siren, L.L.C.",
                "date": "2026-06-30",
                "totalShares": 2.3519,
                "totalAssets": 0.5152,
                "currentShares": 4458646,
                "change": 500000,
                "change_p": 12.6306
            },
            {
                "name": "Bain Capital Life Sciences Investors, LLC",
                "date": "2026-06-30",
                "totalShares": 2.3408,
                "totalAssets": 1.5065,
                "currentShares": 4437731,
                "change": -774943,
                "change_p": -14.8665
            },
            {
                "name": "Bellevue Group AG",
                "date": "2026-06-30",
                "totalShares": 2.1627,
                "totalAssets": 0.4926,
                "currentShares": 4100016,
                "change": -1057274,
                "change_p": -20.5006
            },
            {
                "name": "Geode Capital Management, LLC",
                "date": "2026-06-30",
                "totalShares": 2.1296,
                "totalAssets": 0.0012,
                "currentShares": 4037193,
                "change": 659370,
                "change_p": 19.5206
            },
            {
                "name": "MPM Oncology Impact Management LP",
                "date": "2026-06-30",
                "totalShares": 1.8696,
                "totalAssets": 1.2341,
                "currentShares": 3544354,
                "change": 3544354,
                "change_p": 0
            },
            {
                "name": "Ameriprise Financial Inc",
                "date": "2026-06-30",
                "totalShares": 1.8513,
                "totalAssets": 0.0041,
                "currentShares": 3509623,
                "change": 60502,
                "change_p": 1.7541
            },
            {
                "name": "Great Point Partners LLC",
                "date": "2026-06-30",
                "totalShares": 1.8462,
                "totalAssets": 3.777,
                "currentShares": 3500000,
                "change": 1000000,
                "change_p": 40
            },
            {
                "name": "Adage Capital Partners Gp LLC",
                "date": "2026-06-30",
                "totalShares": 1.8462,
                "totalAssets": 0.028,
                "currentShares": 3500000,
                "change": -800000,
                "change_p": -18.6047
            },
            {
                "name": "Morgan Stanley - Brokerage Accounts",
                "date": "2026-06-30",
                "totalShares": 1.6586,
                "totalAssets": 0.001,
                "currentShares": 3144453,
                "change": 408483,
                "change_p": 14.9301
            },
            {
                "name": "Palo Alto Investors, LLC",
                "date": "2026-06-30",
                "totalShares": 1.5551,
                "totalAssets": 2.326,
                "currentShares": 2948090,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Balyasny Asset Management LLC",
                "date": "2026-06-30",
                "totalShares": 1.4933,
                "totalAssets": 0.0202,
                "currentShares": 2830976,
                "change": -1055933,
                "change_p": -27.1664
            }
        ],
        "Funds": [
            {
                "name": "Fidelity Select Biotechnology",
                "date": "2026-08-31",
                "totalShares": 3.2571,
                "totalAssets": 0.4851,
                "currentShares": 6174755,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "State Street\u00ae SPDR\u00ae S&P\u00ae Biotech ETF",
                "date": "2026-09-30",
                "totalShares": 3.1047,
                "totalAssets": 0.2403,
                "currentShares": 5885821,
                "change": -112500,
                "change_p": -1.8755
            },
            {
                "name": "Vanguard MStar Total Stk Mkt Idx Invest",
                "date": "2026-09-30",
                "totalShares": 3.0178,
                "totalAssets": 0.001,
                "currentShares": 5721196,
                "change": 750560,
                "change_p": 15.0999
            },
            {
                "name": "iShares Russell 2000 ETF",
                "date": "2026-09-30",
                "totalShares": 2.1536,
                "totalAssets": 0.0224,
                "currentShares": 4082748,
                "change": -47040,
                "change_p": -1.139
            },
            {
                "name": "Fidelity Stock Selector Small Cap",
                "date": "2026-07-31",
                "totalShares": 1.0907,
                "totalAssets": 0.1428,
                "currentShares": 2067700,
                "change": 446900,
                "change_p": 27.5728
            },
            {
                "name": "Columbia Acorn Inst",
                "date": "2026-08-31",
                "totalShares": 0.96,
                "totalAssets": 0.3747,
                "currentShares": 1820041,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "Fidelity Small Cap Growth",
                "date": "2026-07-31",
                "totalShares": 0.9429,
                "totalAssets": 0.1035,
                "currentShares": 1787580,
                "change": 547394,
                "change_p": 44.1381
            },
            {
                "name": "Fidelity Small Cap Index",
                "date": "2026-07-31",
                "totalShares": 0.8948,
                "totalAssets": 0.0254,
                "currentShares": 1696340,
                "change": 11859,
                "change_p": 0.704
            },
            {
                "name": "Fidelity Advisor Biotechnology I",
                "date": "2026-08-31",
                "totalShares": 0.8764,
                "totalAssets": 0.3381,
                "currentShares": 1661500,
                "change": 0,
                "change_p": 0
            },
            {
                "name": "iShares Russell 2000 Growth ETF",
                "date": "2026-09-30",
                "totalShares": 0.7773,
                "totalAssets": 0.0442,
                "currentShares": 1473528,
                "change": -1865,
                "change_p": -0.1264
            },
            {
                "name": "Columbia Small Cap Value Discv A",
                "date": "2026-08-31",
                "totalShares": 0.738,
                "totalAssets": 0.274,
                "currentShares": 1399119,
                "change": 8800,
                "change_p": 0.6329
            },
            {
                "name": "Strategic Advisers Fidelity US TtlStk",
                "date": "2026-08-31",
                "totalShares": 0.6884,
                "totalAssets": 0.0024,
                "currentShares": 1305124,
                "change": 203676,
                "change_p": 18.4917
            },
            {
                "name": "iShares Biotechnology ETF",
                "date": "2026-09-30",
                "totalShares": 0.677,
                "totalAssets": 0.0489,
                "currentShares": 1283508,
                "change": -9720,
                "change_p": -0.7516
            },
            {
                "name": "Columbia Small Cap Growth Inst",
                "date": "2026-08-31",
                "totalShares": 0.6438,
                "totalAssets": 0.1711,
                "currentShares": 1220430,
                "change": 0,
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}
Annexon Inc

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Change % vs Prior Year

Revenue, Net Income & Operating Cash Flow (Quarterly)

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